CAS: 4144-62-1; 6-Oxo-6-Phenylhexanoic Acid

该化合物是一种有机化合物,其特点是其碳本体酸功能组和一个苯并硫替代物,通常看起来像白色的,白色的,非白色的固体的,在有机溶剂中可以溶解,尽管其在水中的溶解性有限;该化合物的特性是附于一个苯并硫组的五碳脂链(valeracial),它有助于其独特的化学特性;已知该化合物在有机合成中的潜在应用,以及作为各种药品和农用化学品生产的中间体;该苯并聚体的存在增强了其再活动性,使其在各种化学反应中有用,包括细胞化和酯化;此外,5-苯并valericar酸可能表现出生物活动,尽管关于其药理特性的具体研究可能有限;与许多有机化合物一样,适当的处理和安全防范措施对于潜在的刺激性至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号1444-65-1 2-苯基环己酮 | CAS号827-52-1 环己基苯 | CAS号771-98-2 1-苯基-1-环己烯 | CAS号1792-81-0 顺式-1,2-环己二醇 | CAS号98-83-9 α-甲基苯乙烯 | CAS号1589-60-2 1-苯基环己醇 | CAS号1071-71-2 6-氯-6-氧代己酸乙酯(硫辛酸杂质) | CAS号71-43-2 苯 | CAS号4248-25-3 ethyl 6-oxo-6-p... | CAS号942-93-8 5-chloro-1-phen... | CAS号28353-03-9 6-Oxo-6-phenylh... | CAS号829-14-1 bicyclo[6.4.0]d... | CAS号90665-78-4 methyl 9-oxo-8,... | CAS号56721-39-2 E-Oxo-benzenehe...

合成工艺路线路线简述

    📜1,7-二苯基庚烷-1,7-二酮置于permanganate(Vii) Ion,Sodium Amide,甲苯体系中,化学反应生成 5-苯(甲)酰戊酸
    参考文献:Bauer,Annales De Chimie (Cachan,France),1914,Vol. <9> 1,P. 408
    标题:Bauer,Annales De Chimie (Cachan,France),1914,Vol. <9> 1,P. 408

    海关参考信息

    专利信息


    专利号:US-5936128-A
    优先权日:1993-11-19
    标题:5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents
    发明人:ELLSWORTH EDMUND LEE; LUNNEY ELIZABETH; TAIT BRADLEY DEAN
    权利人:WARNER LAMBERT CO
    摘要:The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.

    专利号:US-5840751-A
    优先权日:1993-11-19
    标题 :5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents
    发明人:ELLSWORTH EDMUND LEE; LUNNEY ELIZABETH; TAIT BRADLEY DEAN
    权利人:WARNER LAMBERT CO
    摘要:The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Wicha, J., Science of Synthesis, (2009) 48, 107.
    摘要:Zhdankin, V. V., Science of Synthesis Knowledge Updates, (2015) 1, 278.
    摘要:Uyanik, M.; Ishihara, K., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 654.
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