CAS: 39890-98-7; 2,6-Dichloro-4-(Trifluoromethyl)Pyridine

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3-三氟甲基戊二酸置于ammonium Hydroxide,五氯化磷,乙酸酐,三氯氧磷体系中,用 水 用作溶剂,化学反应 23.5H,反应生成2,6-二氯-4-三氟甲基吡啶
参考文献:Convenient Approaches To 4-Trifluoromethylpyridine
标题:Convenient Approaches To 4-Trifluoromethylpyridine
摘要:A Number Of Approaches To The Synthesis Of 2-Chloro-And 2,6-Dichloro-4-Trifluoromethylpyridine Are Described. The First Method For 2-Chloro-And 2,6-Dichloro-4-Trifluoromethylpyridine Is Based On Commercially Available Ethyl Trifluoroacetate. An Alternative Access To 2,6-Dichloro-4-Trifluoromethyl Pyridine Uses Trifluoroacetaldehyde As Starting Material. 2-Chloro-4-Trifluoromethylpyridine Is Prepared From Ethyl(Trifluoroacetylvinyl)-Ether In Two Steps.
Doi:10.1021/op000109R

专利信息

专利号:US-11369113-B2
优先权日:2017-10-27
标题:Vector control compositions, methods and products utilizing same
发明人：HUETER OTTMAR FRANZ; HOPPE MARK; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; FEDOU NICOLAS; GODINEAU EDOUARD; WEGE PHILIP; MAIENFISCH PETER
权利人:SYNGENTA PARTICIPATIONS AG
摘要:The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controlling mosquitoes, and to a specific methoxyacrylate compound, processes for the synthesis of mosquitocidal methoxyacrylate compounds and new intermediates.

专利号:CN-107628991-A
优先权日:2017-10-30
标 题 :A kind of synthesis technique of 4-trifluoromethyl nicotinic acid

专利号:RU-2151770-C1
优先权日:1994-06-14
标 题 :Derivatives of pyridone carboxylic acid, methods of their synthesis, antitumor agent and pharmaceutical composition

专利号:US-11286268-B1
优先权日:2019-07-02
标题:EIF4E-inhibiting compounds and methods
发明人：SPERRY SAMUEL; XIANG ALAN X; ERNST JUSTIN T; REICH SIEGFRIED H; SPRENGELER PAUL A; SHAGHAFI MIKE; MICHELS THEO; NILEWSKI CHRISTIAN; TRAN CHINH VIET; PACKARD Garrick Kenneth; GRUBBS ALAN; URKALAN KAVERI; MUKAIYAMA TAKASUKE
权利人:EFFECTOR THERAPEUTICS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. n n n n n n n n n n For Formula I compounds X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , Q, L 1 , L 2 , Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and rings A, B and C are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4e and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.