专利号:US-2024158926-A1 优先权日:2022-11-03 标 题 :Electrochemical synthesis of hydroxyvaleric acid from levulinic acid 发明人:HOLEWINSKI ADAM; DE SOUZA LUCAS FRANCISCO WILLIAN 权利人:UNIV COLORADO REGENTS 摘要:Disclosed herein are methods of electrochemical synthesis of hydroxyvaleric acid from levulinic acid. For example, disclosed herein are methods comprising electrochemical synthesis of hydroxyvaleric acid from levulinic acid, wherein the method is conducted in an electrochemical cell wherein a working electrode is in electrochemical contact with an aqueous electrolyte and levulinic acid, wherein the method comprises applying a potential to electrochemically reduce the levulinic acid to form hydroxyvaleric acid. Also disclosed herein are methods of synthesizing gamma-valerolactone from hydroxyvaleric acid, the method comprising acid-catalyzed esterification. Also disclosed herein are methods of use of the products produced by any of the methods herein.
专利号:US-8080397-B2 优先权日:1999-01-29 标 题 :Biocatalystic synthesis of quinic acid and conversion to hydroquinone by recombinant microbes 发明人:FROST JOHN W; FROST KAREN M 权利人:FROST JOHN W; FROST KAREN M; UNIV MICHIGAN STATE 摘要:A bioengineered synthesis scheme for the production of quinic acid from a carbon source is provided. Methods of producing quinic acid from a carbon source based on the synthesis scheme as well as conversion of quinic acid to hydroquinone are also provided.
专利号:US-6750049-B1 优先权日:1999-03-23 标题 :Synthesis of 1,2,3,4-tetrahydroxybenzenes and 1,2,3-trihydroxybenzenes using myo-inositol-1-phosphate synthase and myo-inositol 2-dehydrogenase 发明人:FROST JOHN W; HANSEN CHAD A 权利人:UNIV MICHIGAN STATE 摘要:A bioengineered synthesis scheme for the production of 1,2,3,4-tetrahydroxybenzene from a carbon source is provided. Methods of producing 1,2,3,4-tetrahydroxybenzene from a carbon source based on the synthesis scheme are also provided. Methods are also provided for converting 1,2,3,4-tetrahydroxybenzene to 1,2,3-trihydroxybenzene by catalytic hydrogenation.
专利号:US-7256251-B2 优先权日:2001-02-06 标 题:Methods of synthesis of polymers and copolymers from natural products 发明人:SWIFT GRAHAM; WESTMORELAND DAVID G; WILLETT JULIOUS L; SHOGREN RANDAL LEE; DOLL KENNETH MICHAEL 权利人:FOLIA INC 摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.
专利号:US-2006052577-A1 优先权日:2001-02-06 标题:Methods of synthesis of polymers and copolymers from natural products 发明人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN 权利人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN 摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.
专利号:US-2009018266-A1 优先权日:2005-11-10 标题 :Preparation of hydrophilic nanoparticles by copolymerization of mono and divinyl monomers in micellar solution 发明人:BORBELY JANOS; HARTMANN JOHN F 权利人:BORBELY JANOS; HARTMANN JOHN F 摘要:The present invention relates to the preparation of hydrophilic nanoparticles and in particular hydrophilic nanoparticles that are biocompatible. Free radical monovinyl-divinyl monomer copolymerization/cross-linking reactions of water-soluble, monovinyl N-vinyl-2-pyrrolidone (NVP) with a bi-unsaturated divinyl, comonomer (poly{ethylene glycol}dimethacrylate) (PEGDMA), has been found to yield hydrophilic nanoparticles (NPs). These nanoparticles are built from three-dimensional nanopolymer networks. In the polymers' synthesis the composition of the monomers, and the total monomer concentration were varied. The characteristics of copolymers were determined by nuclear magnetic resonance spectroscopy (NMR), Fourier transform infrared (FTIR) and elemental analysis. Particle size and morphology of nanoparticles were confirmed by dynamic light scattering (DLS), transmission electron microscope (TEM) and scanning electron microscope (SEM) methods. In the present invention hydrophilic polymers can be used in micellar polymerization to create hydrophilic nanoparticles.