CAS: 10102-25-7; Lithium Sulfate Monohydrate

相似化合物

6108-23-2 6108-17-4 546-89-4

专利信息

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-10047122-B2
优先权日:2013-03-14
标 题 :Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
发明人：QIAN WENJIAN; PARK JUNG EUN; LAI CHRISTOPHER C; KELLEY JAMES A; LEE KYUNG S; BURKE JR TERRENCE R
权利人:THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected phophoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

专利号:WO-2023169432-A1
优先权日:2022-03-08
标题 :Method and system for preparing battery-grade lithium hydroxide and lithium carbonate
发明人：SHI SUYANG; Yong Chenyang; GU ZHIQIANG; GU Yu
权利人:NINGXIA SINOCHEM LITHIUM BATTERY MAT CO LTD; NINGXIA RUITAI TECH CO LTD
摘要:Provided in the present invention are a method and a system for preparing lithium hydroxide and lithium carbonate. The method comprises: (1) synthesis of lithium hydroxide: carrying out at least two stages of causticization reactions on lithium chloride and alkali, and carrying out separation after the reactions to obtain causticization slag of each stage and a last-stage causticization mother liquor, the causticization slag of each stage being a lithium hydroxide crude product; (2) impurity removal for lithium hydroxide: continuously carrying out washing and separation twice or more times on the lithium hydroxide crude product to obtain the last lithium hydroxide washing slag, preparing a solution of the last lithium hydroxide washing slag, and carrying out evaporative crystallization, separation and post-treatment to obtain a lithium hydroxide product; (3) synthesis of lithium carbonate: carrying out evaporative concentration and separation on the last-stage causticization mother liquor to obtain causticization liquid concentrated slag, preparing a solution of the causticization liquid concentrated slag, carrying out a lithium precipitation reaction, and carrying out separation after the reaction to obtain a lithium carbonate crude product; and (4) impurity removal for lithium carbonate: removing impurities from the lithium carbonate crude product to obtain a lithium carbonate product.

专利号:BR-102012016838-A2
优先权日:2012-06-29
标题 :SYNTHESIS OF CYANOACRYLATE MONOMERS FOR AVAILABILITY IN THE PRODUCTION OF TOPIC ADHESIVES

专利号:CN-1196717-C
优先权日:2000-05-29
标 题 :Catalyst for synthesis of alkenes

专利号:CN-1325909-A
优先权日:2000-05-29
标 题:Catalyst for synthesis of alkenes