专利号:US-8975340-B2 优先权日:2010-12-15 标题 :Synthesis of sequestration resins for water treatment in light water reactors 发明人:YENGOYAN LEON; FRATTINI PAUL L; WELLS DANIEL MORGAN 权利人:YENGOYAN LEON; FRATTINI PAUL L; WELLS DANIEL MORGAN; ELECTRIC POWER RES INST 摘要:An organic synthesis of materials to achieve removal of low molecular weight ionic species, such as transition metal ions including cobalt, iron, nickel, and zinc, from aqueous solutions. The synthesis includes the steps of providing a cation exchange resin, functionalizing the cation exchange resin using a chloride intermediate to form a sulfonyl chloride resin, and reacting a multi-amine based ligand with the sulfonyl chloride resin to form a sequestration resin. The synthesis further includes the steps of cooling the sequestration resin, and washing and drying the sequestration resin.
专利号:US-8461357-B2 优先权日:2008-09-19 标题 :Expeditious synthesis of gibberellin A5 and esters thereof 发明人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS RICHARD P 权利人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS R P; UTI LIMITED PARTNERSHIP 摘要:An expeditious synthesis of gibberellin A 5 (GA 5 ) esters is presented, from which GA 5 may be prepared. The synthesis offers an inexpensive route of few steps to these compounds, starting from gibberellin A 3 (GA 3 ) esters in the presence of a metal hydride.
专利号:US-5886104-A 优先权日:1993-06-18 标题 :Grafted cross-linked polyolefin substrates for peptide synthesis and assays 发明人:PEDERSEN WALTHER BATSBERG; ALMDAL KRISTOFFER; WINTHER LARS; BERG ROLF HENRIK 权利人:FORSKNIINGSCENTER RISO 摘要:A solid support for the solid-phase synthesis of peptides or proteins in high yield and in high purity, suited both to the synthesis of a single peptide or protein and to the parallel and substantially simultaneous synthesis of a plurality thereof, is based on a cross-linked polyolefin, especially polyethylene, substrate, the cross-linking having been obtained by irradiation with high energy electrons or γ radiation or treatment with organic peroxide such as benzoyl peroxide, to which substrate are grafted polymer chains such as polystyrene chains which are functionalized with a chemical functionality facilitating the formation of an anchoring linkage between the polymer moiety and another chemical species. The solid support is also suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words, hydrophilic, which makes the solid support particularly well suited for assays of the ELISA type.
专利号:US-7951905-B2 优先权日:2006-09-18 标 题 :Synthesis of carbohydrate-templated amino acids and methods of using same 发明人:SCHWEIZER FRANK; ZHANG KAIDONG; OWENS NEIL; ZHANEL GEORGE 权利人:UNIV MANITOBA 摘要:The present invention generally relates to tetrahydropyranyl-derivatized amino acids, their syntheses and their incorporation into peptides and peptidomimetics. The tetrahydropyran moiety constrains the side chain of an amino acid, thereby providing a molecule that may act as a sugar- or amino acid-mimetic as well as a scaffold for combinatorial synthesis.
专利号:US-7256197-B2 优先权日:2001-10-12 标 题 :Methods for synthesis of diarylmethanes 发明人:ROSOWSKY ANDRE; CHEN HAN 权利人:DANA FARBER CANCER INST INC 摘要:The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; methods of preparation of dihydrofolate reductase inhibitors that include metal mediated cross coupling of an aromatic halide or heteroaromatic halide with an organozinc reagent; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.
专利号:US-5728366-A 优先权日:1994-04-29 标 题:Two powder synthesis of hydrotalcite and hydrotalcite-like compounds with monovalent organic anions 发明人:MARTIN EDWARD S; STINSON JOHN M; CEDRO III VITO; HORN JR WILLIAM E 权利人:ALUMINUM CO OF AMERICA 摘要:There is provided a method for making monovalent organic anion-intercalated hydrotalcite-like materials by first reacting a magnesium-containing powder and a transition alumina powder in a carboxylic acid-free, aqueous suspension to form a meixnerite intermediate. This intermediate is then contacted with a monovalent organic anion to form a hydrotalcite-like material. The latter is then separated from the suspension. Representative materials include a stearate-, acetate- or benzoate-intercalated hydrotalcite-like material.
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合成参考文献
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