CAS: 6276-54-6; 3-Chloropropan-1-Amine Hydrochloride

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116861-31-5 5875-24-1 6435-84-3

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CAS号156-87-6 3-氨基丙醇 | CAS号10554-29-7 N-(3-chloroprop... | CAS号462-47-5 3-巯基-1-丙胺 | CAS号23909-16-2 3-(benzylthio)-... | CAS号88192-19-2 3-叠氮基丙胺 | CAS号2799-72-6 3-氯苯基 异硫氰酸盐 | CAS号73278-98-5 N-3-[3-(1-哌啶甲基)... | CAS号116861-31-5 N-B°C-3-氯丙基胺 | CAS号5407-04-5 3-二甲氨基氯丙烷盐酸盐 | CAS号3420-41-5 2-phenyl-5,6-di... | CAS号34974-00-0 4-PYRIDIN-2-YL-...

3-氨基-1-丙醇置于氯化亚砜体系中,用77 %的收率获得产物3-氯丙胺盐酸盐
参考文献:基于分离和全合成的广泛使用的海洋磺脂类的结构修正
标题:基于分离和全合成的广泛使用的海洋磺脂类的结构修正
摘要:对新报道的一组细菌含硫氨基脂的平面结构进行了修改,并通过分析技术,分离,降解实验和全合成的结合确定了它们的绝对构型.修改后的结构被称为半胱氨酸内酯,与之前基于同牛磺酸的提议不同,揭示了含有被各种(α-羟基)羧酸酰化的头基的半胱氨酸的组成.
DOI:10.1002/anie.202401195

专利信息

专利号:US-4515952-A
优先权日:1982-03-25
标 题 :Synthesis of 2-pyridylalkylamines substituted on the pyridyl ring by bromine
发明人：ADGER BRIAN M; O'ROURKE DAVID J
权利人:SMITH KLINE FRENCH LAB
摘要:The invention provides a process for preparing 2-pyridylalkylamines, substituted in one of the 3- or 5-positions by bromo and in the other by C 1-4 alkyl, by reacting an appropriate C 1-4 alkyl substituted 2-pyridylalkylamine with an electrophilic brominating agent. Said 2-pyridylalkylamines are useful as intermediates in the synthesis of compounds useful as histamine H 1 -antagonists.

专利号:US-6492136-B1
优先权日:1995-12-07
标题 :Solid phase organic synthesis
发明人：FLITSCH SABINE LAHJA; TURNER NICHOLAS JOHN
权利人:GENZYME LTD
摘要:A method of synthesis of a material corresponding to the general formula:characterized in that it comprises a material corresponding to the following general formula:being cleaved as indicated enzymatically or non-enzymatically using acid catalysis in the presence of a nucleophile, wherein: R1 represents a group providing the site for exo-enzyme or acid hydrolysis; R2 represents an intermediate linked to a solid support; R3 represents a carbohydrate, (oligo-)saccharide, (glyco-)peptide, (glyco-)lipid or an organic molecule which is at least one of heterocyclic and aromatic in structure; X represents O, N(H), N(R''), C(O)O, S, C(O)N(H) or C(O)N(R''), R'' being a non-interfering group; and Support represents a solid support.

专利号:US-4526974-A
优先权日:1982-03-25
标 题 :Synthesis of 2-pyridylalkylamines
发明人：ADGER BRIAN M; MASTROCOLA ANTONIETTA R
权利人:SMITH KLINE FRENCH LAB
摘要:The invention provides a process for preparing 2-pyridylalkylamines by reacting an alkali metal derivative of a 2-methylpyridine with a haloalkylamine. The compounds are useful as intermediates in the preparation of compounds having histamine H 1 - and H 2 -antagonist activity.

专利号:EP-1200395-B1
优先权日:1999-07-28
标 题:Urea derivatives as inhibitors of ccr-3 receptor
发明人：PADIA JANAK; HOCKER MICHAEL D; OHASHI HIROSHI; NISHITOBA TSUYOSHI; SAWA EIJI
权利人:KIRIN BREWERY
摘要:Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synthesized using liquid and solid phase synthesis protocols.

专利号:US-4914226-A
优先权日:1986-07-16
标 题 :Malonic acid derivatives and methods for their synthesis
发明人：DI TRAPANI ROMANO; VERDINI ANTONIO S
权利人:ENIRICERCHE SPA; SCLAVO SPA
摘要:The present invention refers to a new class of malonic acid derivatives of general formula I ##STR1## wherein R 1 and R 2 , each independently, represent hydrogen or a carboxyl protecting group, and the residue R corresponds to the side-chain of the amino acids lysine, ornithine, tyrosine, cysteine, asparatic acid and glutamic acid wherein the additional functionalities are suitably protected. The new compounds of the present invention are useful for preparing analogues of biologically active peptides wherein the direction of some amide bonds in which the amino acids lysine, ornithine, tyrosine, cysteine, aspartic acid or glutamic acid are involved, has been reversed.

专利号:US-4424283-A
优先权日:1979-12-13
标 题:Catalyst for synthesizing bisphenol and method for making same
发明人：FALER GARY R; LOUCKS GEROGE R
权利人:GEN ELECTRIC
摘要:A sulfonated organic polymer, such as a sulfonated polystyrene ion-exchange resin is provided having organic mercaptan groups attached to backbone sulfone radicals by covalent nitrogen-sulfur linkages. A method for making such sulfonated organic polymer is also provided. The ion-exchange resin can be used to effect phenol-ketone condensation in the synthesis of bisphenols.