CAS: 6082-04-8; N-((2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(Hydroxymethyl)-2-Methoxytetrahydro-2H-Pyran-3-yl)Acetamide

该化合物是甘蓝胺的衍生物,是甘蓝树脂和甘蓝家庭的成员.该化合物具有甘蓝花表面结构,一种六人组成的循环甘蓝结构,一种六人组成的甘蓝结构,由C-2位置的乙酰胺组和厌食碳的甲基氧基组所修改.它通常是一种白到白的晶状固体,在水和乙醇等极地溶剂中溶解,反映其水利生物特性,因为有羟基和氨基功能组的存在.乙酰胺组有助于其生物活动,使其与各种生物化学应用有关,包括与甘蓝和细胞信号有关的研究.其结构特征还表明其在制药和作为有机合成的构件中的潜在用途.与许多碳水化合物衍生物一样,它可能展示具体的光学活动,可用于其特性和纯度分析技术.

结构式图片

相似化合物

7772-79-4 7772-94-3 3006-60-8

上下游产品

methanol 2-acetamido-3,4,6-tri-O-acetyl-D-glucopyranosyl acetate 2-acetamido-2-deoxy-D-glucose toluene-4-sulfonic acidN-((4aR,6S,7R,8R,8aS)-8-Hydroxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside methyl 6-O-triphenylmethyl-2-acetamido-2-deoxy-α-D-glucopyranoside methyl 2-acetamido-3,4,6-tri-O-methyl-2-deoxy-α-D-glucopyranoside

合成工艺路线路线简述

    📜N-乙酰氨基葡萄糖 以 甲醇 作为反应溶剂,以70%的收率获得产物甲基 2-乙酰氨基-2-脱氧-Alpha-D-吡喃葡萄糖苷
    参考文献:Novel Disaccharides With Anti-Arthrosic Properties
    标题:Novel Disaccharides With Anti-Arthrosic Properties
    摘要:本发明涉及式(i)的新型二糖,其中r1选择自由基,线性或支链(c1-C4)烷基,具有少于十个碳原子的苯基烷基和-Coch3; R2选择自由基,-Coch3和so3M; R3选择自由基,线性或支链(c1-C4)烷基,具有少于十个碳原子的苯基烷基,-Coch3和y-Coph,Ph为苯基; G从-Coor4和-Coom中选择,其中r4选择自由基,(c1-C2)-烷基和具有少于十六个碳原子的芳基烷基; A从自由基,-So3H,-So3M和-Coch3中选择; B从自由基,-So3H,-So3M和-Coch3中选择,其中a或b必须是-So3H或-So3M,M为有机或金属阳离子.该化合物可用作抗关节炎剂,抗炎剂或控制血液凝固剂.

    海关参考信息

    专利信息


    专利号:US-7335500-B2
    优先权日:1991-10-15
    标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
    发明人:WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN
    权利人:SCRIPPS RESEARCH INST
    摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.

    专利号:US-8816050-B2
    优先权日:2006-03-22
    标题:Method of preparing glycopeptides
    发明人:WONG CHI-HUEY; BRIK ASHRAF; YANG YU-YING; FICHT SIMON; PAYNE RICHARD
    权利人:WONG CHI-HUEY; BRIK ASHRAF; YANG YU-YING; FICHT SIMON; PAYNE RICHARD; SCRIPPS RESEARCH INST
    摘要:A method is provided for the synthesis of glycopeptides using a sugar assisted ligation strategy, wherein an N-terminal peptide portion in the form of a thioester is coopled with a C-terminal peptide portion bearing a carbohydrate moiety comprising a thiol group.

    专利号:US-2002068331-A1
    优先权日:1991-10-15
    标题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:D-Glucosamine As A Novel Chiral Auxiliary For The Stereoselective Synthesis Of P-Stereogenic Phosphine Oxides
    作者:A. D'Onofrio,L. Copey,L. Jean-Gérard,C. Goux-Henry,G. Pilet,B. Andrioletti,E. Framery
    摘要:D-Glucosamine Was Successfully Employed As A Chiral Auxiliary For The Enantioselective Synthesis Of Phosphine Oxides. The Influence Of The Anomeric Position Was Also Investigated And Revealed The Excellent Ability Of The α-Anomer To Perform This Transformation In A Highly Selective Fashion. The Methodology Employed Consisted Of Three Steps: Diastereoselective Formation Of The Oxazaphospholidine Followed

    合成参考文献


    摘要:Demchenko, A. V.; De Meo, C., Science of Synthesis Knowledge Updates, (2010) 3, 396.
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