CAS: 554-84-7; 3-Nitrophenol

上下游产品

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1-Allyloxy-3-Nitro-Benzene置于氢氧化钾体系中,用 甲醇 作为反应溶剂,化学反应 9.0H,以97%的收率获得产物间硝基苯酚
参考文献:Palladium Charcoal-Catalyzed Deprotection Of O-Allylphenols
标题:Palladium Charcoal-Catalyzed Deprotection Of O-Allylphenols
摘要:Allyl Aryl Ethers Can Be Easily Cleaved By The Use Of 10% Pd/c Under Mild And Basic Conditions. The Present Reaction Would Involve A Set Process Rather Than A Pi-Allyl-Palladium Complex. The Scope And Limitation Of This New Deprotective Methodology Is Also Described. (C) 2004 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2004.05.097

专利信息

专利号:US-5545568-A
优先权日:1992-09-14
标题:Solid phase and combinatorial synthesis of compounds on a solid support
发明人：ELLMAN JONATHAN A
权利人:UNIV CALIFORNIA
摘要:Methods, compositions, and devices for synthesizing combinatorial libraries of various useful compounds, such as benzodiazepines, prostaglandins, β-turn mimetics and glycerol-derived drugs is described. In order to expediently synthesize such combinatorial libraries of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.

专利号:US-2003138880-A1
优先权日:2001-08-24
标 题:Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases
发明人：WITHERS STEPHEN G; JENSEN KNUD J; PETERSEN LARS; TOLBORG JAKOB L
权利人:UNIV BRITISH COLUMBIA
摘要:The present invention provides materials and methods for the solid-phase synthesis of oligosaccharides and glycopeptides. Such materials and methods include mutant glycosidase enzymes, or “glycosynthases,â€? chemically-derivatized acceptor molecules, and specific solid support matrices.

专利号:US-2025002505-A1
优先权日:2021-10-05
标题 :Synthesis of macroyclic compounds
发明人：PAL BIMAN; LIU JING; MARTIN KEVIN; ZHANG HAN
权利人:TURNING POINT THERAPEUTICS INC
摘要:The present disclosure provides new methods of preparing a compound of Formula (I). Such methods can prepare the compound at any scale, including gram and kilogram scale.

专利号:US-4157344-A
优先权日:1978-01-16
标题 :Preparation of aryl trifluoromethyl ethers
发明人：FEIRING ANDREW E
权利人:DU PONT
摘要:A one-step process for the synthesis of aryl trifluoromethyl ethers by reacting phenol or certain substituted phenols with a perhalomethane and hydrogen fluoride is provided. The compounds produced by the process of this invention are useful intermediates in the production of dyestuffs and pharmaceuticals.

专利号:US-9885035-B2
优先权日:2002-10-30
标 题 :Method for the synthesis of a bifunctional complex
发明人：FRANCH THOMAS; GOULIAEV ALEX HAAHR
权利人:NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more reactants, and provided with respective tag(s) identifying the reactant(s) at the priming site is using one or more enzymes.

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).