专利号:US-2016185745-A1 优先权日:2013-08-07 标题:Analogs of vinaxanthone and xanthofulvin, methods of synthesis, and methods of treatments thereof 发明人:SIEGEL DIONICIO; CHIN MATTHEW; ELIASEN ANDERS; AXELROD ABRAM 权利人:UNIV TEXAS 摘要:The present invention relates generally to methods of synthesis of vinaxanthone and xanthofulvin, novel analogs, and methods of use thereof.
专利号:US-9522932-B2 优先权日:2004-03-04 标 题 :Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production 发明人:HERDEWIJN PIET; PANNECOUQUE CHRISTOPHE; WU TONGFEI; DE CLERCQ ERIK 权利人:LEUVEN K U RES & DEV 摘要:The invention is directed to a process for the preparation of substituted threonolactone and substituted threose compounds which are intermediates in the synthesis of phosphonate nucleosides being useful antiviral agents.
专利号:US-10065924-B2 优先权日:2014-07-22 标 题 :Preparation and biological evaluation of viridicatumtoxin analogs 发明人:NICOLAOU KYRIACOS C; HALE CHRISTOPHER R H; NILEWSKI CHRISTIAN; IOANNIDOU HERAKLIDIA; EL MARROUNI ABDELLATIF 权利人:UNIV RICE WILLIAM M 摘要:In one aspect, the present invention provides novel derivatives of viridicatumtoxin of the formula wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synthesis thereof.
专利号:US-4656291-A 优先权日:1985-03-15 标 题 :Process for producing amidine sulfonic acids 发明人:MARYANOFF CYNTHIA A; PLAMPIN JAMES N; STANZIONE ROBIN C 权利人:MCNEILAB INC 摘要:An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): with H2O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
专利号:US-4781866-A 优先权日:1985-03-15 标题 :Process for producing amidine sulfonic acid intermediates for guanidines 发明人:MARYANOFF CYNTHIA A; PLAMPIN JAMES N; STANZIONE ROBIN C 权利人:MCNEILAB INC 摘要:An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): with H2O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
专利号:US-4851094-A 优先权日:1985-03-15 标 题:Process for producing amidine sulfonic acid intermediates for guanidines 发明人:MARYANOFF CYNTHIA A; PLAMPIN JAMES N; STANZIONE ROBIN C 权利人:MCNEILAB INC 摘要:An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): (III) (II) with H2O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.