CAS: 3424-82-6; O,P'-Dde

该化合物是一种化学化合物,是杀虫剂滴滴涕(二氯二苯基三氯乙烷)的分解产物,被归类为有机氯化合物,并因其在环境中的持久性而闻名,导致食物链中的生物累积.o,p 欧元-二氯乙烷的特点是其亲脂性,允许其在生物体脂肪组织中蓄积.该化合物经常被研究其内分泌干扰性,因为它会干扰野生动物和人类的激素系统.其化学结构有两种氯化苯基环,附在双壳乙烷组中,有助于其稳定性和抗降解性.由于其对环境和健康的影响,o,欧洲-二氯乙烷在各种生态研究和监管评估中受到监测.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

o,p'-DDT 1-Chloro-2-o-chlorophenyl-2-p'-chlorophenylethylene iron(III) chloride 2-chlorophenylmagnesium bromide1-(2-chlorophenyl)-1-(4-chlorophenyl)acetic acid 2,4'-dichlorobenzophenone 2,4'-dichloro-benzophenone-(2,4-dinitro-phenylhydrazone)

合成工艺路线路线简述

    📜(2-Chlorophenyl)Magnesium Bromide置于sodium Hydroxide,乙醚,硫酸体系中,化学反应生成2,4'-滴滴伊
    参考文献:The Chemical Composition Of Technical Ddt1
    标题:The Chemical Composition Of Technical Ddt1
    摘要:
    Doi:10.1021/ja01225A058

    海关参考信息

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: A K Wójtowicz, Et Al. Ddt- And Dde-Induced Disruption Of Ovarian Steroidogenesis In Prepubertal Porcine Ovarian Follicles: A Possible Interaction With The Main Steroidogenic Enzymes And Estrogen Receptor Beta. J Physiol Pharmacol. 2007 Dec;58(4):873-85.
    [参考文献]: Anna A Kasperlik-Zaluska, Et Al. Clinical Role Of Determination Of Plasma Mitotane And Its Metabolites Levels In Patients With Adrenal Cancer: Results Of A Long-Term Follow-Up. J Exp Ther Oncol. 2005;5(2):125-32.
    [参考文献]: Ilse G Hermsen, Et Al. Plasma Concentrations Of O,P'Ddd, O,P'Dda, And O,P'Dde As Predictors Of Tumor Response To Mitotane In Adrenocortical Carcinoma: Results Of A Retrospective Ens@t Multicenter Study. J Clin Endocrinol Metab. 2011 Jun;96(6):1844-51.
    [参考文献]: Lori K Davis, Et Al. Effects Of O,P'-Dde, Heptachlor, And 17Beta-Estradiol On Vitellogenin Gene Expression And The Growth Hormone/insulin-Like Growth Factor-I Axis In The Tilapia, Oreochromis Mossambicus. Comp Biochem Physiol C Toxicol Pharmacol. 2009 May;149(4):507-14.
    [参考文献]: Marielle Thomas, Et Al. Organochlorine Pesticides And Polychlorinated Biphenyls In Sediments And Fish From Freshwater Cultured Fish Ponds In Different Agricultural Contexts In North-Eastern France. Ecotoxicol Environ Saf. 2012 Mar:77:35-44.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1002/etc.5620200924|10.1897/1551-5028(2001)020<2038:soecfe>2.0.co;2
    摘要:Dinan L, Bourne P, Whiting P, Dhadialla TS, Hutchinson TH. Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster B(II) cell in vitro assay. Environ Toxicol Chem. 2001 Sep;20(9):2038–46. doi: 10.1897/1551-5028(2001)020<2038:soecfe>2.0.co;2.
    参考文献:10.1007/s00244-005-7001-1
    摘要:Wong HL, Giesy JP, Lam PKS. Organochlorine Insecticides in Mudflats of Hong Kong, China. Archives of Environmental Contamination and Toxicology. 2005 Nov 21;50(2):153–65. doi: 10.1007/s00244-005-7001-1.
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