CAS: 22950-29-4; Dimetofrine
该化合物是属于酚化合物类别的化学化合物,其特点是以氢氧基和甲氧基组物替代的苯环,有助于其潜在的生物活动;甲基氨基组物的存在表明,它可能表现出与矿物质化学有关的特性,可能影响其溶解性和再活性.该化合物在室温下很固,并且可能具有中度至高度的极极性,因为存在功能组物.该化合物的结构表明,在制药或生物化学探测器中可能应用,尽管具体生物活动将取决于进一步的经验研究.应当象对任何化学物质一样,考虑安全数据和处理预防措施,以确保适当的实验室做法.
- 英文名称Dimetofrine
- 中文名称二甲福林
- IUPAC名称4-(1-hydroxy-2-(methylamino)ethyl)-2,6-dimethoxyphenol
- 其它别名Benzylalcohol, 4-hydroxy-3,5-dimethoxy-a-[(methylamino)methyl]- (7CI,8CI); 1-(3,5-Dimethoxy-4-hydroxyphenyl)-2-(methylamino)ethanol; 4-Hydroxy-3,5-dimethoxy-a-[(methylamino)methyl]benzyl alcohol; Anassicol; Dimethophrine; Dimetofrine; Dimetrophine
- CAS编号22950-29-4
- FDA UNII编号:BOM1J10QQM
- 分子式:C11H17NO4分子量:227.26
- 产品CID: 1169566
- 产品分类有机原料 → 苯类化合物 → 酚类
物理性质
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2906210000-苄醇
2907210001-间苯二酚
2907221000-对苯二酚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
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主要参考文献
1: McClellan KJ, Wiseman LR, Wilde MI. Midodrine. A review of its therapeutic use in the management of orthostatic hypotension. Drugs Aging. 1998 Jan;12(1):76-86. doi: 10.2165/00002512-199812010-00007. 51(8):1025; discussion 1025-9. 38(5):757-77. doi: 10.2165/00003495-198938050-00004. Erratum in: Drugs 1990 Feb;39(2):followi. 43(6):523-38. 244(3):1011-5. 64(1):61-8. Italian. 9(8):578-85. doi: 10.1185/03007998509109637. 9(2):78-85. doi: 10.1185/03007998409109563. 9(4):265-74. doi: 10.1185/03007998409109590. 96(6):643-6. Italian. 29(1):17-21. Italian. 32(3):205-11. Italian. 27(1):158-61. 79(4):347-60. Italian. 26(11):2038-9. 26(10):1857-60. 23(6-7):403-5. Italian. 29(11):665-70. Italian. 113(7):392-6. Italian. 29(5):238-42. Italian.
合成参考文献
参考文献:10.1007/bf00297587
摘要:Montagna M, Groppi A. Fatal sotalol poisoning. Arch Toxicol. 1980 Jan;43(3):221–6. doi: 10.1007/bf00297587.
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