CAS: 157335-94-9; Methyl 4-Methylpyrimidine-5-Carboxylate
该化合物是一种具有制药和农用化学合成用途的微米碘衍生物,其结构包括一个碳箱酸酯酯和一个甲基替代成分,使它成为制造复杂的七环化合物的多用途中间体,该酯组通过水解或核循环替代促进进一步功能化,而该甲基组则增强稳定性和影响反应力.该化合物在药用化学中对于发展动脉抑制剂和其他生物活性分子特别宝贵.其高纯度和持续性能确保了研究和工业过程的可靠结果.建议在标准实验室条件下进行适当处理以保持其完整性.
- 英文名称Methyl 4-Methylpyrimidine-5-Carboxylate
- 中文名称4-甲基嘧啶-5-羧酸甲酯
- IUPAC名称methyl 4-methylpyrimidine-5-carboxylate
- 其它别名4-甲基-5-嘧啶甲酸甲酯; 5-Pyrimidinecarboxylicacid,4-Methyl-,Methylester(9Ci)
- CAS编号157335-94-9
- MFCD编号:MFCD12923211
- 分子式:C7H8N2O2分子量:152.15
- 产品CID: 786266
- 产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物
相似化合物
157335-92-7 832090-44-5 110960-73-1物理性质
MSDS等安全信息
合成工艺路线路线简述
📜3-Dimethylaminomethylenepentane-2,4-Dione,甲脒 以50%的收率获得
参考文献:Kress Thomas J.,Heterocycles,38 (1994) N 6,S 1375-1385
标题:Kress Thomas J.,Heterocycles,38 (1994) N 6,S 1375-1385
海关参考信息
- 2912110000-甲醛
2915110000-甲酸
2909199090-其他醚及其衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-9717969-A1
优先权日:1995-11-16
标题 :Dihydropyrimidines and uses thereof
发明人：NAGARATHNAM DHANAPALAN; WONG WAI C; MIAO SHOU WU; PATANE MICHAEL A; GLUCHOWSKI CHARLES
权利人:SYNAPTIC PHARMA CORP; MERCK & CO INC; NAGARATHNAM DHANAPALAN; WONG WAI C; MIAO SHOU WU; PATANE MICHAEL A; GLUCHOWSKI CHARLES
摘要:This invention is directed to dihydropyrimidine compounds which are selective antagonists for human alpha 1A receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of begnin prostatic hyperplasia, impotency, cardiac arrythmia and for the treatment of any disease where the antagonism of the alpha 1A receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.
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📌 第三方产品分析报告
主要参考文献
参考标题:Copper-Catalyzed One-Pot Synthesis Of Pyrimidines From Amides, N ,N ′-Dimethylformamide Dimethylacetal, And Enamines作者:Hitesh B. Jalani,Wangshui Cai,Hongjian Lu |发布日期:2017.7.17
摘要:Versatile Copper Catalyzed One‐pot Synthesis Of Diversely Substituted Pyrimidines Directly From Amides, N,N′‐dimethylformamide Dimethylacetal (Dmf−dma) And Enamines Has Been Established. The Reaction Involved The Two C−n Bonds And One C−c Bond Formation By Formal [2+1+3] Annulation Approach To Pyrimidines. This Protocol Is Based On The Use Of Readily Available Primary Amides, Dmf−dma And Enamines To
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