CAS: 14335-29-6; 2-Amino-1-((Diphenylboranyl)Oxy)Ethan-1-One

相似化合物

524-95-8 124383-92-2 2622-89-1

上下游产品

oxybis(diphenylborane) sodium glycinate diphenylborinic acid glycine

📜二苯基酸置于盐酸体系中,用 乙醚,乙醇,水 用作溶剂,化学反应 4.0H,反应生成甘氨酰二苯基硼酸
参考文献:In Vitro Apoptotic Activity Of 2,2-Diphenyl-1,3,2-Oxazaborolidin-5-Ones In L5178Y Cells
标题:In Vitro Apoptotic Activity Of 2,2-Diphenyl-1,3,2-Oxazaborolidin-5-Ones In L5178Y Cells
摘要:Compounds Containing B-N Bonds Have Shown Interesting Biological Activity. One Class Of Such Molecules Is The 2,2-Diphenyl-1,3,2Oxazaborolidin-5-Ones (3A-J),Which Contain A B-N Bond,Have An Alpha-Amino Acid Moiety In The Heterocycle,And Have An Exocyclic Moiety Related To An Amino Acid. The Purpose Of This Work Was To Determine The Inhibitory Effects Of 3A-J On The Proliferation Of Murine L5178Y Lymphoma Cells. A New Five-Membered Heterocyclic Nucleus With Apoptotic Activity Was Found. The Target Products Showed Potent Cytotoxicity In The L5178Y Cell Line. Among Them,3A Exhibited The Highest Antineoplastic Activity In L5178Y Cells With An Ic50 Value Of 22.5 +/-0.2 Mu M. (C) 2006 Elsevier Inc. All Rights Reserved.
Doi:10.1016/j.Lfs.2006.11.034