CAS: 1125-88-8; Benzaldehyde Dimethyl Acetal

相似化合物

707-07-3 707-07-3 24856-58-4

上下游产品

CAS号100-52-7 苯甲醛 | CAS号149-73-5 原甲酸三甲酯 | CAS号67-56-1 甲醇 | CAS号707-07-3 原苯甲酸三甲酯 | CAS号681-84-5 原硅酸四甲酯 | CAS号108-88-3 甲苯 | CAS号119-53-9 2-羟基-2-苯基苯乙酮 | CAS号292638-84-7 phenylene-ethylene | CAS号28867-76-7 苄连氮 | CAS号1825-61-2 甲氧基三甲基硅烷 | CAS号105873-87-8 5-nitro-1-[(5-n... | CAS号105873-94-7 1-[methoxy(phen... | CAS号1084-08-8 [diethoxyphosph... | CAS号5425-44-5 2-苯基-1,3-二噻烷 | CAS号5764-85-2 3-羟基-3-苯基丙酸乙酯 | CAS号3695-84-9 2-氰基-3-苯基丙烯酸甲酯 | CAS号36283-44-0 (R)-N-(1-苯乙基)乙酰胺 | CAS号4148-71-4 甲基-2,3:4,6-二-O-... | CAS号400091-05-6 4-甲氧苯基-3-O-烯丙基-... | CAS号98-85-1 苏合香醇

二氯甲基苯置于zinc(II) Chloride,原甲酸三甲酯体系中,用 Neat (No Solvent) 用作溶剂,化学反应 48.0H,反应生成苯甲醛二甲缩醛
参考文献:催化剂性质对4-(二溴甲基)苯甲醛与原甲酸三烷基酯反应产物结构的影响
标题:催化剂性质对4-(二溴甲基)苯甲醛与原甲酸三烷基酯反应产物结构的影响
摘要:在布朗斯台德酸(h 2 So 4)和路易斯酸(zncl 2)酸存在下,4-(二溴甲基)苯甲醛与原甲酸三烷基酯的反应涉及醛基的缩醛化.在第一种情况下,形成相应的缩醛作为唯一产物,而在第二种情况下,反应伴随有二溴甲基的转化,生成对苯二醛及其单缩醛和双缩醛.
Doi:10.1134/s1070363217120052

专利信息

专利号:US-9446995-B2
优先权日:2012-05-21
标 题:Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN-SOON; ILLINOIS INST OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-10189803-B2
优先权日:2008-02-22
标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-11566040-B2
优先权日:2019-01-28
标题:Synthesis of O-antigen oligosaccharide compounds of Helicobacter pylori serotype O2
发明人：YIN JIAN; HU JING; LIU ZHONGHUA; QIN CHUNJUN
权利人:UNIV JIANGNAN
摘要:Disclosed is synthesis of an O-Antigen oligosaccharide compound of Helicobacter pylori serotype O2, belonging to the field of organic synthesis. The disclosure obtains O-antigen disaccharide to tetracosasaccharide of Helicobacter pylori serotype O 2 by chemical synthesis. A chemical synthesis method which is quite conducive to production of a glucose-α-lglucosidic bond is developed in the disclosure by a protectant strategy, temperature effect, solvent effect, and additive effect. The method is applied in synthesis of an O-antigen oligosaccharide compound of Helicobacter pylori serotype O2 assembled with an amino linking arm. A saccharide conjugate can be prepared from the synthesized O-antigen oligosaccharide compound of Helicobacter pylori serotype O2 assembled with an amino linking arm together with a carrier protein for immunology researches, playing an important role in preventing and treating Helicobacter pylori.

专利号:EP-2070941-A1
优先权日:2007-12-14
标 题 :Stereoselective synthesis of selective estrogen receptor down-regulators
权利人:BAYER SCHERING PHARMA AG; ASTRAZENECA AB
摘要:The present invention relates to stereoselective synthesis of 7-α-substituted estra-4-ene-3,17-diones. Such compounds are valuable intermediates in the synthesis of 7-α-substituted estra-1,3,5(10)-triene-3,17-diols. n Key step in this synthesis is reacting a 3-keto-4,6-estradiene with a Grignard reagent selected from the group consisting of a magnesium-halide alkyl halide having at least 3 carbon atoms, a magnesium-halide alkenyl halide having at least 3 carbon atoms, and a magnesium-halide alkynyl halide having at least 3 carbon atoms, in the presence of a catalyst system comprising CuI. n The obtained 7α-alkyl, alkenyl and alkynyl halides can be used for the synthesis of pharmaceutically actice 7-α-substituted estra-1,3,5(10)-triene-3,17-diols (antiestrogens).

专利号:US-2004058888-A1
优先权日:2000-01-13
标题:Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides
发明人：BORNAGHI LAURENT; DEKANY GYULA; DRINNAN NICHOLAS BARRY; PAPAGEORGIOU JOHN; WEST MICHAEL LEO
摘要:This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising α-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of α-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R 3 is methoxy or methyl; R 1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R 2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4 -chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.

专利号:US-2013267680-A1
优先权日:2010-09-15
标题:Total chemical synthesis of ubiquitin, ubiquitin mutants and derivatives thereof
发明人：OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL
权利人:OVAA HUIB; EL OUALID FARID; MERKX REMCO NICOLAAS SEBASTIAAN MICHEL; STICHTING HET NL KANKERINST
摘要:The present invention relates to the field of total chemical synthesis of ubiquitin and related peptides. More in particular, a method is provided of solid phase synthesis of ubiquitin, ubiquitin mutants and derivatives thereof. It was the object of the present invention to provide an approach for the total chemical synthesis of ubuiqitin, which allows for the chemical synthesis of virtually any Ub mutant and giving high overall efficiency and purity. The present inventors have surprisingly found that this object can be realized with a method relying on incorporation of special amino acid building blocks. This approach was found to allow for exceptionally high yields of up to 14% and to provide an synthetic entry into virtually any ubiquitin derivative.