CAS: 69120-06-5; 5-(6-Hydroxybenzofuran-2-yl)-2-(3-Methylbut-2-En-1-yl)Benzene-1,3-Diol
该化合物是天然发生的化合物,被归类为氟氯素,具体来说是一种酸盐,主要来自莫罗萨亚植物家族,特别是包括穆尔莓在内的古草原莫鲁斯.Moracin C展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性,从而引起对药理研究的兴趣.该化合物的结构具有典型的铬骨干特征,有助于其再活动以及与各种生物目标的相互作用.Moracain C是有机溶剂的溶液,其稳定性可能受到光和温度等环境因素的影响.对Moracin C的研究强调了其潜在的治疗应用,尽管还需要进一步研究,以充分阐明其在临床环境中的行动和功效机制.与许多自然产品一样,提取和净化过程对于以适合研究和潜在治疗用途的形式获得甲状腺素C至关重要.
- 英文名称5-(6-Hydroxybenzofuran-2-yl)-2-(3-Methylbut-2-En-1-yl)Benzene-1,3-Diol
- 中文名称5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇
- IUPAC名称5-(6-hydroxybenzofuran-2-yl)-2-(3-methylbut-2-en-1-yl)benzene-1,3-diol
- 其它别名5-(6-Hydroxy-1-Benzofuran-2-yl)-2-(3-Methylbut-2-En-1-yl)Benzene-1,3-Diol ; 5-(6-Hydroxy-1-Benzouran-2-yl)-2-(3-Methylbut-2-Enyl)Benzene-1,3-Diol ; Tgz4Gh2N64 ; 2-(3,5-Dihydroxy-4-Prenylphenyl)-6-Hydroxybenzofuran ; 5-(6-Hydroxy-1-Benzofuran-2-yl)-2-(3-Me
- CAS编号69120-06-5
- MFCD编号:MFCD20274766
- FDA UNII编号:TGZ4GH2N64
- 分子式:C19H18O4分子量:310.34
- 产品CID: 1686380
- 产品分类有机原料→分子砌块→芳杂环类化合物→苯并呋喃类化合物
相似化合物
1429209-60-8 67736-18-9 1838-44-4物理性质
MSDS等安全信息
上下游产品
2,4-diacetoxybenzaldehyde 2-(3,5-dimethoxyphenyl)-6-hydroxybenzofuran 3,5-dimethoxybenzoic acid 5-acetoxy-2-acetoxymethylphenol moracin D合成工艺路线路线简述
📜2-(3,5-二甲氧基苯基)苯并呋喃-6-醇置于咪唑,正丁基锂,二苯基膦体系中,用 四氢呋喃,正己烷,环己烷 作为反应溶剂,化学反应 40.5H,反应生成 桑辛素 C; 5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇
参考文献:Total Synthesis Of The 2-Arylbenzo[b]Furan-Containing Natural Products From Artocarpus
标题:Total Synthesis Of The 2-Arylbenzo[b]Furan-Containing Natural Products From Artocarpus
摘要:In This Study,2-Arylbenzo[b]Furan-Containing Derivatives Moracin C (1) And Moracin M (4),The Natural Products From Artocarpus,Have Been Synthesized In Highest Overall Yield To Date (1,7 Steps With An Overall Yield Of 41.9%; 4,6 Steps With An Overall Yield Of 56.3%),And We Also Report The First Total Synthesis Of Artoindonesianin B-1 (2),Another Member Of This Family,In The Same Route (8 Steps With An Overall Yield Of 11.3%). This Discovery Provides A Concise Route For Preparing Enough Amounts Of 1,2,And 4 As Well As 2-Arylbenzo[b]Furan-Containing Natural Product-Like Analogs (71-74) To Explore The Biological Potential. (C) 2015 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2015.05.093
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2907221000-对苯二酚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:CN-113564140-A
优先权日:2020-04-28
标 题:Three FAD-dependent enzymes in mulberry and their application in the synthesis of Diels-Alder adducts
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Lv M, Jiang S, Deng S, Zhao Z, Yang Z, Liu L, Ke T. Discovery and Characterization of Moracin C as an Anti-Gouty Arthritis/Hyperuricemia Candidate by Docking-Based Virtual Screening and Pharmacological Evaluation. J Nat Prod. 2023 Sep 22;86(9):2091-2101. doi: 10.1021/acs.jnatprod.3c00099. Epub 2023 Aug 25.
9:666647. doi: 10.3389/fchem.2021.666647.
3: Masagalli JN, BasavanaGowda MK, Chae HS, Choi WJ. Synthesis of Moracin C and Its Derivatives with a 2-arylbenzofuran Motif and Evaluation of Their PCSK9 Inhibitory Effects in HepG2 Cells. Molecules. 2021 Mar 2;26(5):1327. doi: 10.3390/molecules26051327.
合成参考文献
参考文献:10.3390/molecules16076010
摘要:Yang ZG, Matsuzaki K, Takamatsu S, Kitanaka S. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16(7):6010–22.
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