CAS: 640-60-8; Phenyl P-Toluenesulfonate

该化合物是一种有机化合物,是有机合成中重要的试剂,其特征是存在一个附于一种抗合物的苯基组,这种聚苯酸从p-tulenesulfonic酸中衍生出来,该聚苯醚一般是无色的,在标准条件下,其稳定性为浅黄色液体,苯乙烯类同系物主要用作核循环替代反应中的遗留组,在合成各种有机化合物中具有价值.其再活动可归结于亚合物组,该聚物会增强苯性环的电益性,便利核分裂.此外,苯类同质在有机溶剂中是可溶的,例如二氯甲烷和乙醚,但在水中的溶性有限.安全考虑包括谨慎处理它,因为它可能刺激皮肤和眼睛.

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ECHA物质C&L通报

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CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号108-95-2 苯酚 | CAS号1529-17-5 三甲基苯氧基硅 | CAS号455-16-3 对甲苯磺酰气氟 | CAS号103-19-5 对甲苯二硫醚 | CAS号6293-66-9 二苯基碘鎓对甲苯磺酸盐 | CAS号104-15-4 对甲苯磺酸 | CAS号25491-50-3 Thallous Phenoxide | CAS号4096-21-3 1-苯基吡咯烷 | CAS号4096-20-2 N-苯基哌啶 | CAS号3526-43-0 N-苯基-4-甲氧基苄胺 | CAS号54879-64-0 N-[(4-甲氧基苯基)甲基]... | CAS号104-15-4 对甲苯磺酸 | CAS号108-95-2 苯酚 | CAS号93-89-0 苯甲酸乙酯 | CAS号92-53-5 4-苯基吗啉 | CAS号5123-13-7 苯硼酸新戊烷乙二醇酯 | CAS号21784-96-3 n-Butyl p-tolyl...

合成工艺路线路线简述

    📜(4-溴苯基)4-甲基苯磺酸盐置于nickel(II) Iodide,1,4-双(二环己基膦)丁烷,Sodium Carbonate,Cesium Iodide体系中,用 四氢呋喃 作为反应溶剂,化学反应 72.25H,以61%的收率获得产物对甲苯亚磺酸苯酯
    参考文献:镍催化的芳基溴化物的光脱卤
    标题:镍催化的芳基溴化物的光脱卤
    摘要:在这里,我们描述了在利用四氢呋喃作为氢源的可见光照射下镍催化的芳基溴化物的光脱卤.该方案消除了对外源胺还原剂或光催化剂的需求,其特点是简单易行且适用范围广,包括具有挑战性的底物组合
    DOI:10.1055/a-1457-2399

    海关参考信息

    专利信息


    专利号:US-7026339-B2
    优先权日:2003-11-07
    标题 :Inhibitors of HCV NS5B polymerase
    发明人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
    权利人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
    摘要:The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.

    专利号:US-10253165-B2
    优先权日:2015-02-26
    标 题 :Control of organic impurities in polycarbonate synthesis
    发明人:BOJARSKI AARON DAVID; GARCIA AGUDO JORGE A
    权利人:SABIC GLOBAL TECHNOLOGIES BV
    摘要:Polymerization processes comprising melt polymerizing a carbonate and a dihydroxy compound in the presence of an amount of a beta organic catalyst so as to give rise to a polycarbonate product, wherein the amount of beta organic catalyst comprises at least one onium salt and also comprises triphenyl phosphonium oxide (TPPO), and wherein the TPPO represents less than about 0.3 weight % of the sum of the weights of the at least one onium salt and the TPPO in the amount of beta organic catalyst.

    专利号:US-10150111-B2
    优先权日:2016-09-06
    标题 :Method for catalytic synthesis of cinnamic acid with catalyst recycle

    专利号:US-9895454-B2
    优先权日:2014-07-03
    标题:Metal oxide catalyzed radiofluorination
    发明人:SERGEEV MAXIM; MORGIA FEDERICA; VAN DAM ROBERT MICHAEL; LAZARI MARK
    权利人:UNIV CALIFORNIA
    摘要:Inter alia, the first titania-catalyzed [ 18 F]-radiofluorination in highly aqueous medium is provided. In embodiments, the method utilizes titanium dioxide, 1:1 acetonitrile-thexyl alcohol solvent mixture and tetrabutylammonium bicarbonate as a base. Radiolabeling may be directly performed with aqueous [ 18 F]fluoride without the need for drying/azeotroping step, which reduces radiosynthesis time while keeping high fluoride conversion. The general applicability of the synthetic strategy to the synthesis of the wide range of PET probes from tosylated precursors is demonstrated.

    专利号:US-2018326410-A1
    优先权日:2016-09-06
    标题 :Method for catalytic synthesis of cinnamic acid with catalyst recycle

    专利号:US-2020048410-A1
    优先权日:2017-04-14
    标 题:Synthesis of a phosphorous containing monomer and the incorporation in polycarbonate by interfacial polymerization thereof

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Palladium Nanoparticles As Reusable Catalyst For The Synthesis Of N-Aryl Sulfonamides Under Mild Reaction Conditions
    作者:Mehdi Khalaj,Majid Ghazanfarpour-Darjani,Mohamad Reza Talei Bavil Olyai,Sakineh Faraji Shamami |发布日期:2016.3.3
    摘要:An Efficient Palladium Nanoparticles-Catalyzed N-Arylation Of Sulfonamides And Sulfonyl Azides Is Described. This Procedure Serves As An Active Protocol For Intermolecular C-N Bond Formation Using Pd(Oac)2 In Peg-400 Under Air. Aryl Bromides And Triflates React At 35°C, While Aryl Chlorides Require Heating To 50°C And Give The Desired Products Only In Low Yields. This Reaction Proceeds Smoothly In

    合成参考文献


    摘要:Virieux, D.; Ayad, T.; Pirat, J.-L.; Volle, J.-N., Science of Synthesis Knowledge Updates, (2018) 1, 292.
    摘要:Wolf, C., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 863.
    摘要:Eichman, C. C.; Stambuli, J. P., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 378.
    摘要:Hay, M. B.; Hicks, J. D., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 127.
    摘要:Hay, M. B.; Hicks, J. D., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 163.
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