专利号:US-7026339-B2 优先权日:2003-11-07 标题 :Inhibitors of HCV NS5B polymerase 发明人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY 权利人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY 摘要:The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.
专利号:US-10253165-B2 优先权日:2015-02-26 标 题 :Control of organic impurities in polycarbonate synthesis 发明人:BOJARSKI AARON DAVID; GARCIA AGUDO JORGE A 权利人:SABIC GLOBAL TECHNOLOGIES BV 摘要:Polymerization processes comprising melt polymerizing a carbonate and a dihydroxy compound in the presence of an amount of a beta organic catalyst so as to give rise to a polycarbonate product, wherein the amount of beta organic catalyst comprises at least one onium salt and also comprises triphenyl phosphonium oxide (TPPO), and wherein the TPPO represents less than about 0.3 weight % of the sum of the weights of the at least one onium salt and the TPPO in the amount of beta organic catalyst.
专利号:US-10150111-B2 优先权日:2016-09-06 标题 :Method for catalytic synthesis of cinnamic acid with catalyst recycle
专利号:US-9895454-B2 优先权日:2014-07-03 标题:Metal oxide catalyzed radiofluorination 发明人:SERGEEV MAXIM; MORGIA FEDERICA; VAN DAM ROBERT MICHAEL; LAZARI MARK 权利人:UNIV CALIFORNIA 摘要:Inter alia, the first titania-catalyzed [ 18 F]-radiofluorination in highly aqueous medium is provided. In embodiments, the method utilizes titanium dioxide, 1:1 acetonitrile-thexyl alcohol solvent mixture and tetrabutylammonium bicarbonate as a base. Radiolabeling may be directly performed with aqueous [ 18 F]fluoride without the need for drying/azeotroping step, which reduces radiosynthesis time while keeping high fluoride conversion. The general applicability of the synthetic strategy to the synthesis of the wide range of PET probes from tosylated precursors is demonstrated.
专利号:US-2018326410-A1 优先权日:2016-09-06 标题 :Method for catalytic synthesis of cinnamic acid with catalyst recycle
专利号:US-2020048410-A1 优先权日:2017-04-14 标 题:Synthesis of a phosphorous containing monomer and the incorporation in polycarbonate by interfacial polymerization thereof
参考标题:Palladium Nanoparticles As Reusable Catalyst For The Synthesis Of N-Aryl Sulfonamides Under Mild Reaction Conditions 作者:Mehdi Khalaj,Majid Ghazanfarpour-Darjani,Mohamad Reza Talei Bavil Olyai,Sakineh Faraji Shamami |发布日期:2016.3.3 摘要:An Efficient Palladium Nanoparticles-Catalyzed N-Arylation Of Sulfonamides And Sulfonyl Azides Is Described. This Procedure Serves As An Active Protocol For Intermolecular C-N Bond Formation Using Pd(Oac)2 In Peg-400 Under Air. Aryl Bromides And Triflates React At 35°C, While Aryl Chlorides Require Heating To 50°C And Give The Desired Products Only In Low Yields. This Reaction Proceeds Smoothly In
合成参考文献
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