CAS: 506-21-8; (9E,12E)-Octadeca-9,12-Dienoic Acid

该化合物是一种由linolecial酸衍生的跨脂肪酸,其特点是独特的双重结合配置.它是一种不饱和脂肪酸,其化学结构包括18个碳原子和两个双联,特别是跨组合.这种结构安排影响其物理特性,使其在室温下通常固化,不同于其液态的Cis对等液酸.Linolelaidic酸主要存在于部分氢化植物油中,可在脂肪工业加工过程中产生.它存在于饮食中,引起健康问题,因为跨脂肪酸与心血管疾病和其他健康问题的更大风险有关.在溶性,硅酸在有机溶剂中溶解,但水溶性有限.它的分子配方是C18H34O2,并且经常在营养和食品科学的背景下加以研究,特别是其对人类健康和新陈代谢的影响.

结构式图片

相似化合物

60-33-3 506-43-4 112-63-0

上下游产品

(Z,Z)-9,12-十八烷二烯酸二聚物 Linoleic Acid 60-33-3
十八碳-9,12-二烯酸甲酯 Linoleic Acid Methyl Ester 2462-85-3
Methyl Ricinoleate 41989-07-5

合成工艺路线路线简述

    📜16-Bromo-Hexadeca-6,9-Diene置于丙酮,Sodium Iodide体系中,化学反应生成 亚麻酸
    参考文献:Baudart,Bulletin De La Societe Chimique De France,1944,Vol. <5>11,P. 338
    标题:Baudart,Bulletin De La Societe Chimique De France,1944,Vol. <5>11,P. 338

    海关参考信息

    专利信息


    专利号:US-9643915-B2
    优先权日:2013-03-15
    标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-9708354-B2
    优先权日:2013-03-15
    标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
    发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
    权利人:CERENIS THERAPEUTICS HOLDING SA
    摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

    专利号:US-10604479-B2
    优先权日:2013-11-18
    标 题:Continuous process for the one-pot synthesis of metal salts and metal complexes
    发明人:LEONARDI GIULIANO; GASPERONI GIOVANNI
    权利人:VOLARE & CONNECTING LLC; LEONARDI GIULIANO; NOVUS INT INC
    摘要:A continuous process is described for the one-pot synthesis of compounds, such as metal salts and metal complexes, as well as optionally for the protection of the compounds thus obtained by coating and/or impregnation with suitable compounds.

    专利号:US-11583842-B2
    优先权日:2019-07-24
    标题 :Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis
    发明人:YEUNG YING-YEUNG; LAM YING-PONG; KE ZHIHAI; WANG XINYAN; TAN FEI; NG WING-HIN; TSE YING-LUNG STEVE
    权利人:UNIV HONG KONG CHINESE
    摘要:An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

    专利号:US-11981938-B2
    优先权日:2017-10-05
    标 题 :Microorganisms and methods for the fermentation of cannabinoids
    发明人:SZAMECZ BELA KRISZTIAN; VARSZEGI SZILVIA; NEMETH ATTILA; SZABO LORAND; KUMAR ABHINAV
    权利人:ELESZTO GENETIKA INC
    摘要:Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ9-tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabichromenic acid (CBCA), Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), cannabichromene (CBC). Enzymes useful for the synthesis of CBGA and cannabinoids, include but are not limited to acyl activating enzyme (AAE1), polyketide synthase (PKS), olivetolic acid cyclase (OAC), prenyltransferase (PT), THCA synthase (THCAS), CBDA synthase (CBDAS), CBCA synthase (CBCAS), HMG-Co reductase (HMG1), and/or farnesyl pyrophosphate synthetase (ERG20). The microorganisms can also have one or more genes disrupted, such as gene that that controls beta oxidation of long chain fatty acids.

    专利号:WO-2014152883-A1
    优先权日:2013-03-14
    标 题 :Method for synthesis of sub 100-nm indium nanoparticles
    发明人:KRAMER THEODORE J
    权利人:LIQUID LIGHT INC
    摘要:The present disclosure generally relates to a method for the synthesis and production of indium nanoparticles. More particularly, disclosed is a method of making indium nanoparticles in a nonpolar solvent. The indium nanopatl icles are prepared by reducing an indium fatty acid carboxylate in the presence of a surfactant. Indium is a useful electrocatalyst and electrode material for performing certain electrochemical reactions. Because electrochemical reactions generally occur on the electrode surface, a high surface area of electrode material, or material coated on an electrode is desirable. One way to achieve high surface area is to use a coating of small particles such as nanoparticles.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Jay Whelan, Et Al. Linoleic Acid. Adv Nutr. 2013 May 1;4(3):311-2.

    合成参考文献


    参考文献:10.4103/0971-4065.82131
    摘要:Boutabet K, Kebsa W, Alyane M, Lahouel M. Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin. Indian J Nephrol. 2011 Apr;21(2):101–6.
    参考文献:10.1186/1472-6882-11-57
    摘要:Teke GN, Lunga PK, Wabo HK, Kuiate J, Vilarem G, Giacinti G, Kikuchi H, Oshima Y. Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica Stend ex A. Satabie. BMC Complementary Medicine and Therapies. 2011 Jul 19;11(1):57. doi: 10.1186/1472-6882-11-57.
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