CAS: 3261-87-8; 1,4-Oxathiane-2,6-Dione

相似化合物

89603-16-7 855398-78-6 54772-29-1

上下游产品

CAS号123-93-3 2,2'-硫代二乙酸 | CAS号108-24-7 乙酸酐 | CAS号75-36-5 乙酰氯 | CAS号70648-87-2 2-[(2-苯胺基-2-氧代乙... | CAS号99184-85-7 (1,3-苯并噻唑-2-甲基)硫代]乙酸 | CAS号61363-69-7 methyl 2-(2-chl...

硫代二乙酸置于乙酰氯体系中,化学反应 4.0H,以65%的收率获得产物硫代羟基乙酸酐
参考文献:大环二氧杂,二硫杂,二氮杂内酰胺及其衍生物的合成与结构
标题:大环二氧杂,二硫杂,二氮杂内酰胺及其衍生物的合成与结构
摘要:描述了18元二恶英,二硫杂和二氮杂四内酰胺的高产率逐步合成.这两个关键步骤是:I)二酸通过其环酐的反应异构化,以及ii)避免高稀释技术的中间二酰胺二酸的活化环化.制备了两种二氮杂四内酰胺衍生物:带有各种取代基的双支化化合物和带有菲咯啉单元的大双环或大三环物种.通过13 C NMR和分子建模发现二氧杂内酰胺的主要构象异构体具有d 2对称性,而在真空中的双硫杂四内酰胺和固态的boc取代的二氮杂内酰胺具有c 2对称性.
DOI:10.1016/0040-4020(96)00529-7

专利信息

专利号:US-4130565-A
优先权日:1976-11-05
标 题:Novel type of oxa- and thia-steroids
发明人：TERASAWA TADAO; OKADA TOSHIHIKO
权利人:SHIONOGI & CO
摘要:16-Oxa- and 16-thia-D-homo-estrogen derivatives useful as postcoital oral contraceptives which are produced by total synthesis from 1-vinyltetralin-1-ols or their thiuronium derivatives on reactions with 4-substituted tetrahydropyran- or tetrahydrothiopyran-3,5-diones, and subsequent appropriate modifications.

专利号:WO-2024264014-A1
优先权日:2023-06-22
标题:Synthesis of glp-1r/gipr agonists and precursors thereof
发明人：KRISHNAN SHYAM; FERRARI THOMAS; LIU YADONG; WANG XIAOFANG; GAO RUI; XIAO FENGPING; XIE ZHIFENG; LIU YANPENG
权利人:CARMOT THERAPEUTICS INC; KRISHNAN SHYAM; FERRARI THOMAS; LIU YADONG; WANG XIAOFANG; GAO RUI; XIAO FENGPING; XIE ZHIFENG; LIU YANPENG
摘要:The present disclosure provides a novel synthetic method for preparing GLP-1R/GIPR agonists. Also provided is a synthetic method for preparing 2-((2-oxo-2-((2-(2-oxopiperidin-1-yl)ethyl)amino)ethyl)thio)acetic acid.