CAS: 3099-52-3; 2-(Diethylamino)Ethyl Nicotinate

该化合物是尼基锡酸(乙基)和二乙基氨基乙醇的合成酯衍生物,该化合物主要用于制药和生化研究,因为其潜在的血管和胆碱基特性,其结构特征,包括硝基丁酸和三级矿物质组,有助于其在水溶剂和有机溶剂中的溶解性,便于配方灵活性.该酯联系增强了代谢稳定性,允许在生理系统中有控制地释放.应用可能包括对周边循环的研究或药物开发的中间体.建议,在惰性条件下适当处理和储存以保持稳定.分析特征通常涉及HPLC,NMR和质谱测量.

结构式图片

MSDS等安全信息

    上下游产品

    CAS号93-60-7 烟酸甲酯 | CAS号100-37-8 二乙氨基乙醇 | CAS号20260-53-1 盐酸烟酰氯 | CAS号10400-19-8 烟酰氯 | CAS号59-67-6 烟酸 | CAS号56-23-5 四氯化碳

    合成工艺路线路线简述

      📜烟酸置于氯化亚砜,苯体系中,化学反应生成烟胺乙酯
      参考文献:Mndshojan,Zhurnal Obshchei Khimii,1946,Vol. 16,P. 1033,1035
      标题:Mndshojan,Zhurnal Obshchei Khimii,1946,Vol. 16,P. 1033,1035

      海关参考信息

      专利信息


      专利号:US-12221646-B2
      优先权日:2013-07-04
      标 题:Method for the rapid determination of susceptibility or resistance of bacteria to antibiotics
      发明人:FERNÃ?NDEZ GARCÃ?A JOSÉ LUIS; GOSÃ?LVEZ BERENGUER JAIME; SANTISO BRANDARIZ REBECA; TAMAYO NOVAS MARIA; BOU ARÉVALO GERMÃ?N
      权利人:ABM TECH LLC
      摘要:A method of rapidly evaluating the susceptibility of a strain of bacteria to a cell wall synthesis inhibiting antibiotic based on an assessment of cell enlargement in response to doses of the cell wall synthesis inhibiting antibiotic which are correlated to breakpoints of bacterial susceptibility.

      专利号:US-2023398101-A1
      优先权日:2022-06-09
      标题 :Co-agents as Therapy Against Anaerobic Pathogens
      发明人:PACE JOHN LEE; HARTSELL THERESA LYNN
      权利人:FLEURIR ABX LLC
      摘要:Co-agent combinations and/or formulations herein unexpectedly display significantly better antimicrobial activity (e.g., more efficacy and/or more potency) against anaerobic pathogens not previously considered targets. With three or more co-agents, selected from a group of a fosfomycin, a diaminopyridine, a sulfonamide, a beta lactam antibacterial, a bacterial beta-lactamase inhibitor, a bacterial fosfomycin-modifying enzyme, and a bacterial peptidoglycan synthesis inhibitor, the therapeutic potential of the three or more co-agents is expanded by targeting a broader spectrum of pathogens. Co-agents, by unexpected synergistic action in an anaerobic environment, are now active and efficacious against difficult to treat pathogenic anaerobes (including anaerobes that cannot utilize oxygen and/or reside in an anaerobic environment, some being inhibited by oxygen), as well as pathogens considered resistant or intolerant to at least one of the co-agents when used singly in an anaerobic environment. Some co-agent combinations and/or formulations contain one or more existing antibiotic agents being repurposed for utility against difficult to treat anaerobic pathogens.

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      主要参考文献

      1. Wang TA, Wu TH, Pan SL, Chen HH, Chiu SY. Impacts of treatments on recurrence and 28-year survival of ischemic stroke patients. Sci Rep. 2021 Jul 27;11(1):15258. doi: 10.1038/s41598-021-94757-6. 2. Lee TK, Chan KW, Huang ZS, Ng SK, Lin RT, Po HL, Yuan RY, Lai ML, Chang TW, Yan SH, Deng JC, Liu LH, Lee KY, Lie SK, Sung SM, Hu HH. Effectiveness of low-dose ASA in prevention of secondary ischemic stroke, the ASA Study Group in Taiwan. Thromb Res. 1997 Jul 15;87(2):215-24. doi: 10.1016/s0049-3848(97)00121-7.

      合成参考文献


      摘要:Pharmazie., 11(242), 1956 []
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