CAS: 2021-28-5; Ethyl 3-Phenylpropionate

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CAS号103-36-6 肉桂酸乙酯 | CAS号4192-77-2 反式肉桂酸乙酯 | CAS号108-86-1 溴苯 | CAS号140-88-5 丙烯酸乙酯 | CAS号98-80-6 苯硼酸 | CAS号501-52-0 3-苯丙酸 | CAS号105-58-8 碳酸二乙酯 | CAS号2216-94-6 苯基丙炔酸乙酯 | CAS号14371-10-9 桂皮醛 | CAS号64-17-5 乙醇 | CAS号108357-95-5 1,5-diphenylpen... | CAS号607-81-8 苄基丙二酸二乙酯 | CAS号31984-10-8 1-溴-4-苯基丁-2-酮 | CAS号41162-19-0 2-氧代-4-苯丁基磷酸二甲酯 | CAS号220580-60-9 5-Phenethyloxazole | CAS号22767-95-9 Benzenepropanoi... | CAS号122-97-4 3-苯丙醇 | CAS号5848-56-6 (3-ethoxypropyl... | CAS号104-53-0 3-苯丙醛 | CAS号5406-39-3 3-(对甲苯基)丙烷-1-醇

2-苄基乙酰乙酸乙酯置于甲醇,Sodium Bromide体系中,用92%的收率获得3-苯丙酸乙酯
参考文献:Electrochemical Deacetylation Of 1,3-Dicarbonyl Compounds
标题:Electrochemical Deacetylation Of 1,3-Dicarbonyl Compounds
摘要:通过卤锪离子介导的电解,成功实现了1,3-二羰基化合物的温和去乙酰化.在此反应中,支持电解质的包含钠卤化物nax(x = Cl或br)是至关重要的,因为反应通过阳极电化学生成的卤锪离子在活性次甲基碳上的取代进行,紧接着是碱催化的去乙酰化,并在阴极通过还原脱卤终止于形成的α-卤代羰基化合物.
Doi:10.1246/cl.1996.143

专利信息

专利号:US-10533028-B2
优先权日:2014-09-04
标 题:Ruthenium complexes and their uses as catalysts in processes for formation and/or hydrogenation of esters, amides and related reactions
发明人：MILSTEIN DAVID; HU PENG; FOGLER ERAN; RAO JAI ANAND GARG NARAYANA
权利人:YEDA RES & DEV
摘要:The present invention relates to novel Ruthenium complexes of formulae A1-A4 and their use, inter alia, for (1) dehydrogenative coupling of alcohols to esters; (2) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (3) preparing amides from alcohols and amines—(including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or polymerization of amino alcohols and/or forming cyclic dipeptides from p-aminoalcohols; (4) hydrogenation of amides (including cyclic dipeptides, polypeptides and polyamides) to alcohols and amines; (5) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (6) dehydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water and a base to form carboxylic acids; and (10) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. The present, invention further relates to the use of certain known Ruthenium complexes for the preparation of amino acids or their salts from amino alcohols.

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

专利号:US-12145139-B2
优先权日:2016-02-09
标题 :Manganese based complexes and uses thereof for homogeneous catalysis
发明人：MILSTEIN DAVID; NERUSH ALEX; VOGT MATTHIAS; MUKHERJEE ARUP; ESPINOSA-JALAPA NOEL ANGEL; CHAKRABORTY SUBRATA
权利人:YEDA RES & DEV; NERUSH ARKADI
摘要:The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C—C coupling in Michael addition reaction using nitriles as Michael donors; (3) dehydrogenative coupling of alcohols to give esters and hydrogen gas (4) hydrogenation of esters to form alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (5) hydrogenation of amides (including cyclic dipeptides, lactams, diamide, polypeptides and polyamides) to alcohols and amines (or diamine); (6) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (7) dehydrogenation of secondary alcohols to ketones; (8) amidation of esters (i.e., synthesis of amides from esters and amines); (9) acylation of alcohols using esters; (10) coupling of alcohols with water and a base to form carboxylic acids; and (11) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. (12) preparation of amides (including formamides, cyclic dipeptides, diamide, lactams, polypeptides and polyamides) by dehydrogenative coupling of alcohols and amines; (13) preparation of imides from diols.

专利号:US-2023151034-A1
优先权日:2020-03-17
标题:Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
发明人：JACOBSON IRINA C; LEE SAM SK; PIZARRO NOVOA JUAN CARLOS
权利人:COCRYSTAL PHARMA INC
摘要:Peptidomimetic N5-methyl-N2-(nonanoyl-L-leucyl)-L-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds for use in methods of inhibiting the replication of noroviruses and coronaviruses in a biological sample or patient, for use in reducing the amount of noroviruses or coronaviruses in a biological sample or patient, and for use in treating norovirus and coronavirus in a patient, comprising administering to said biological sample or patient a safe and effective amount of a compound represented by formulae I or II, or a pharmaceutically acceptable salt thereof. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. page 99 to page 271; examples 1 to 3; compounds A1 to A104 and B1 to B66; tables A to E).

专利号:FR-2602508-A1
优先权日:1986-08-07
标 题 :PROCESS FOR THE SYNTHESIS OF HETEROCYCLES FROM PALLADOCYCLIC COMPLEXES

专利号:CN-105567652-A
优先权日:2014-10-14
标题:A Ketoreductase and Its Application in Asymmetric Synthesis of Chiral Hydroxyl Compounds