CAS: 13106-53-1; 1-Hexadecyl-4-Methylpyridinium Chloride Hydrate

该化合物是长氢丁烯烷链和正电荷环.该化合物通常具有表面活性特性,在各种应用中有用,包括生物杀灭剂,抗微生物剂和个人护理产品的配方.其结构由氮原子六十二基苯组和四级甲基组所替代,有助于其非phyphicic性质.氯离子作为反向平衡的正电荷.由于其长期的湿性尾巴,该化合物在水中往往具有低溶性,但可与生物膜相互作用,从而可能提高其在抗微生物应用中的功效.此外,在一系列pH条件下,该化合物可能具有稳定性,使之适合各种配方.应当参考安全数据,以便处理和潜在毒性,因为四氟化铵化合物可以是刺激剂,并构成环境关切.

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CAS号108-89-4 4-甲基吡啶 | CAS号4860-03-1 氯代十六烷 | CAS号133216-97-4 (1-Hexadecyl-4-... | CAS号544-77-4 1-碘十六烷 | CAS号80241-43-6 (4-Pyridinylmet...

合成工艺路线路线简述

    📜4-吡啶基甲基膦酸置于sodium Hydroxide体系中,用 水,乙腈 用作溶剂,化学反应生成1-正十六烷基-4-甲基吡啶氯盐,水合物
    参考文献:Surface-Active Properties And Their Photochemical Behaviors Of (1-Alkyl-4-Pyridiniomethyl)Phosphonates
    标题:Surface-Active Properties And Their Photochemical Behaviors Of (1-Alkyl-4-Pyridiniomethyl)Phosphonates
    摘要:(制备出了带有碳数为 8 至 18 的偶数长烷基链的(1-烷基-4-吡啶基甲基)膦酸盐.它们具有表面活性剂的特征.在碱性水介质中照射时,膦酸盐发生 C-P 键裂解,反应生成1-烷基-4-甲基吡啶鎓膦酸盐,因此溶液的表面张力也发生了变化.在它们的临界胶束浓度下,C-P 键裂解的量子产率增加了两倍.
    Doi:10.1246/bcsj.63.3053

    海关参考信息

    专利信息


    专利号:US-5110929-A
    优先权日:1986-08-07
    标题 :Process for the preparation of N-alkylated quaternary nitrogen containing aromatic heterocycles
    发明人:PARADIES HENRICH H
    权利人:MEDICE CHAM PHARM FABRIK PUTTE
    摘要:The synthesis of 4-, 4-(1,1)-and 3,5-substituted N-alkyl-pyridinium salts as well as of 2-carboxamide substituted N(1,4)diazinium compounds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10-5 -10-7 Mol/Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharmaceuticals.

    专利号:US-5112844-A
    优先权日:1986-08-07
    标 题:Imidazole derivatives and use as anti-bacteria, anti-fungal and anti-viral agents
    发明人:PARADIES HENRICH H
    权利人:PUETTER MEDICE CHEM PHARM
    摘要:The synthesis of quaternary five membered N-n-alkyl-heterocycles, especially of 4-hydroxy-N(1)-n-alkyl-imidazolium, 2,5-substituted N(3)-n-alkyl-thiazolium and substituted N(2) pyrazolium salts are described. The N-surfactants obtained have a very small critical micelle concentration (CMC) of 10-5-10-7 Mol/Liter, and are capable of forming micelles of different sizes and forms depending on the nature of the anions. The N-detergents can be used as pharmaceuticals.

    专利号:US-5118808-A
    优先权日:1986-08-07
    标 题 :Pharmaceutical preparations
    发明人:PARADIES HENRICH H
    权利人:PUETTER MEDICE CHEM PHARM
    摘要:The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration (CMC) in the order of 10 -5 -10 -7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

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