CAS: 1254-85-9; Ac1Mj135

该化合物是一种类固醇衍生物,其特点是一种复杂的多环状体结构,典型为甲状腺类和甲状腺类和甲状腺类,其特点是多种功能组,包括一个呋喃环,氢氧基化合物和一种环氧基化合物,这些物质有助于其生物活动和潜在的药用特性.

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上下游产品

Cedrelone acetate Cedrelonacetat Acetic acid (3S,8R,10R,13S,14R,15R,17S)-17-furan-3-yl-3-hydroxy-4,4,8,10,13-pentamethyl-7-oxo-3,4,7,8,9,10,11,12,13,15,16,17-dodecahydro-20-oxa-cyclopropa[14,15]cyclopenta[a]phenanthren-6-yl ester 6-acetoxy-7α-hydroxy-3-oxo-14β,15β-epoxymeliac-1,5-diene

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    主要参考文献


    1: Wu J, Niu Q, Yuan J, Xu X, Cao L. Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1. Exp Ther Med. 2019 Dec;18(6):4209-4220. doi: 10.3892/etm.2019.8080. Epub 2019 Oct 7.
    2: Cao Y, Zhang L, Wang Y. Antitumor activity of Cedrelone in temozolomide- resistant human glioma cells is accompanied by mitochondrial mediated apoptosis, inhibition of angiogenesis, cell cycle disruption and modulation of ERK/MAPK signalling pathway. J BUON. 2019 May-Jun;24(3):1204-1209.
    316:108920. doi: 10.1016/j.cbi.2019.108920. Epub 2019 Dec 16. 13(10):1645-53. doi: 10.2174/18715206113139990314. 19(1):764. doi: 10.1186/s12885-019-5914-8.

    合成参考文献


    参考文献:10.1021/jf025534t
    摘要:Suresh G, Gopalakrishnan G, Wesley SD, Pradeep Singh ND, Malathi R, Rajan SS. Insect antifeedant activity of tetranortriterpenoids from the Rutales. A perusal of structural relations. J Agric Food Chem. 2002 Jul 31;50(16):4484–90. doi: 10.1021/jf025534t.
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