CAS: 78418-01-6; 2-Hydroxy-5-Octanoylbenzoic Acid

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CAS号78417-96-6 methyl 2-hydrox... | CAS号111-64-8 辛酰氯 | CAS号69-72-7 水杨酸 | CAS号119-36-8 水杨酸甲酯 | CAS号78417-90-0 salifluor

辛酰氯置于sodium Hydroxide,三氯化铝体系中,用 二硫化碳,乙醇 作为反应溶剂,化学反应 18.0H,反应生成 5-辛酰水杨酸
参考文献:Potential Salicylamide Antiplaque Agents: In Vitro Antibacterial Activity Against Actinomyces Viscosus
标题:Potential Salicylamide Antiplaque Agents: In Vitro Antibacterial Activity Against Actinomyces Viscosus
摘要:A Series Of 55 Salicylamides,Including 3,5-Dibromo-,5-N-Alkyl-,And 5-N-Acylsalicyloyl Derivatives Of Various Anilines,Heterocyclic Amines,Benzylamines,And Alkylamines,Was Synthesized And Evaluated For In Vitro Antibacterial Activity Against Actinomyces Viscosus,An Adherent Oral Microorganism Implicated In Periodontal Disease. The In Vitro Minimum Inhibitory Concentrations Of 15 4'-Bromosalicylanilides Were Found To Correlate (R = 0.92) With Estimated Log D Values. Several Nonhalogenated Salicylanilides,Such As 5-N-Hexyl-(40) And 5-N-Decanoyl-4'-Nitrosalicylanilide (47),Were Found To Exhibit Higher Levels Of In Vitro Antibacterial Activity Against A Number Of Actinomycetes Than Did Tribromsalan (1) Or Fluorophene (2).
DOI:10.1021/jm00142A023

专利信息

专利号:US-7662401-B2
优先权日:2002-04-08
标 题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
发明人：MAHE YANN; MEYBECK ALAIN
权利人:OREAL
摘要:The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.

专利号:US-6264962-B1
优先权日:1997-12-19
标 题:Use of cinnamic acid or of at least one of its derivatives in a cosmetic composition
发明人：BRETON LIONEL; GIRERD FLORENCE; RENAULT BEATRICE
权利人:OREAL
摘要:The invention relates to the use of cinnamic acid, or of at least one of its derivatives, in a cosmetic composition as an agent for promoting the synthesis of the skin's total lipids. n The invention also relates to a cosmetic composition comprising an effective amount of cinnamic acid or of at least one of its derivatives.

专利号:US-6660283-B2
优先权日:1997-12-19
标 题 :Use of cinnamic acid, or of at least one of its derivatives in a cosmetic composition
发明人：BRETON LIONEL; GIRERD FLORENCE; RENAULT BEATRICE
权利人:OREAL
摘要:The invention relates to the use of cinnamic acid, or of at least one of its derivatives, in a cosmetic composition as an agent for promoting the synthesis of the skin's total lipids.The invention also relates to a cosmetic composition comprising an effective amount of cinnamic acid or of at least one of its derivatives.

专利号:US-4701527-A
优先权日:1983-12-05
标 题 :Synthesis of salicylamides with improved reaction kinetics and improved effective yields
发明人：KOERMER GERALD S; GUTIERREZ EDDIE N; PROROK MARYFRANCES
权利人:LEVER BROTHERS LTD
摘要:A method of synthesizing with improved reaction kinetics and improved effective yields salicylamide compounds of the formula: or wherein R1 is a substituent selected from the group consisting of -H, -COCnH2n+1 and -CnH2n+1 wherein n is an integer with a value of from 1 through to about 15, R2 is a substituent selected from the group consisting of -H, -CN, -NO2, -F, -Cl, -Br, -I, -CF3, -CBr3, -CCl3, -CI3 and R1 and R3 is an R2 substituted heterocyclic compound selected (e.g.) from the group consisting of furan, thiazole, benzothiazole and purine which comprises reacting a phenyl salicylate ester bearing an R1 substituent on the benzene ring of the salicylic acid portion thereof with an R2 substituted aniline or a heterocyclic amine NH2-R3 and with a Lowry-Bronsted acid catalyst, optionally in the presence of an inert solvent such as a halogenated or unhalogenated aromatic compound or a polyethylene glycol of average molecular weight 1000 to 6000 or mixtures thereof at a temperature of above about 150 DEG C. for about one half to about 4 hours. When the Lowry-Bronsted acid catalyst takes the form of the hydrochloride salt of the reactant aniline or heterocyclic amine the amount of the free reactant aniline or heterocyclic amine is reduced proportionately.

专利号:US-2006141078-A1
优先权日:2004-11-10
标题:Composition comprising a rice protein hydrolysate and an agent for increasing glycosaminoglycan synthesis
发明人：GUILLOU VERONIQUE; THIRY ANNABELLE
权利人:OREAL
摘要:The present invention relates to a process for preventing and/or reducing the signs of ageing of the skin, in particular for remodelling the face and/or limiting the age-related hollowing of the face, by applying to facial skin a composition containing, in a physiologically acceptable medium, at least one rice protein hydrolysate and at least one agent for increasing glycosaminoglycan synthesis.

专利号:US-2003224077-A1
优先权日:2002-04-08
标 题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase