CAS: 7147-90-2; 5-Chloroisoindoline-1,3-Dione

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CAS号118-45-6 4-氯代苯酐 | CAS号89-20-3 4-氯邻苯二酸 | CAS号50-84-0 2,4-二氯苯甲酸 | CAS号544-92-3 氰化亚铜 | CAS号3676-85-5 4-氨基邻苯二甲酰亚胺 | CAS号57-13-6 尿素 | CAS号56047-23-5 4-氯代邻苯二甲酸单钠盐 | CAS号89-40-7 4-硝基邻苯二甲酰亚胺 | CAS号96385-49-8 4-CHLOROPHTHALAMIDE | CAS号111130-30-4 4-chloro-5-nitr... | CAS号623-03-0 对氯苯腈 | CAS号89-77-0 2-氨基-4-氯苯甲酸 | CAS号6015-57-2 4-氯-5-硝基邻苯二甲酰亚胺 | CAS号123594-04-7 4-氯异吲哚啉 | CAS号96385-49-8 4-CHLOROPHTHALAMIDE | CAS号5566-48-3 5-氨基-6-氯异吲哚啉-1,3-二酮

4-氯邻苯二酸置于ammonium Carbonate体系中,化学反应 2.0H,以91%的收率获得产物4-氯酞酰亚胺
参考文献:6,7-二取代的1(2H)-和3,4-二氢-1(2H)-酞嗪酮的合成,利尿和降压活性.
标题:6,7-二取代的1(2H)-和3,4-二氢-1(2H)-酞嗪酮的合成,利尿和降压活性.
摘要:异构体系列6-氯-7-氨磺酰基-和7-氯-6-氨磺酰基-1(2H)-酞嗪酮(1和2)以及6-氯-7-氨磺酰基和7-氯-6-描述了氨磺酰基-3,4-二氢-1(2H)-酞嗪酮(3和4),结合了速尿和肼苯哒嗪的特征结构特征,讨论了1和2的形成机理,以及它们的结构-活性关系被研究.在大鼠中的初步筛选显示,系列1和3具有与氯噻嗪相似的利尿和利尿活性,但是na + / K +比氯噻嗪和呋塞米更有利.系列2和4的化合物实际上是惰性的.所有四个系列的初始降压活性均低于肼苯哒嗪.但是,化合物1A,1C,
DOI:10.1021/jm00156A011

专利信息

专利号:WO-9102739-A1
优先权日:1989-08-11
标题:Synthesis of glycosides having predetermined stereochemistry
发明人：DANISHEFSKY SAMUEL J
权利人:UNIV YALE
摘要:Methods of stereoselectively preparing a substituted 1,2-anhydrosugar wherein a substituted glycal is converted into a 1,2-anhydrosugar that is utilized to glycosylate a hydroxyl group containing glycal, are disclosed. Methods of preparing a saccharide multimer wherein a nucleophile is reacted with a substituted 1,2-anhydrosugar having a plurality of non-participating substituents, are disclosed. In addition, methods of preparing stereospecific halo-substituted saccharide multimers by haloglycosylation of a glycosyl donor substituted glycal and a glycosyl acceptor glycal derivative in the absence of water and in the presence of a halonium ion, are disclosed. Methods of preparing stereospecific particle-linked halo-substituted saccharide multimers, by haloglycosylation of a particle-linked nucleophilic hydroxyl group with a substituted glycal and a halonium ion, are also disclosed.

专利号:US-3965125-A
优先权日:1971-02-08
标题:Synthesis of certain bis(phthalic anhydrides)
发明人：MEYERS ROBERT A
权利人:TRW INC
摘要:Monomeric high molecular weight dianhydrides or tetraacids can be produced by the nucleophilic coupling of a halo substituted phthalimides acid and an aliphatic or aromatic compound having polyfunctional groups capable of reacting with the halo moiety of the phthalinide followed by hydrolysis and dehydration. Specifically, 4-chlorophthalate sodium salt is converted to an imide to reduce side reactions with the carboxylic acid groups prior to reaction with 4,4'-disodiumdiphenylene oxide sulfone or 2,2-di (4-sodium phenoxide) propane. After the reaction of the imide and the sulfone or propane compounds, the diimide formed is converted to the corresponding dianhydride.

专利号:US-5278301-A
优先权日:1990-03-23
标 题:Route to glycals in the allal and gulal series
发明人：HALCOMB RANDALL L; DANISHEFSKY SAMUEL J; WITTMAN MARK D
权利人:UNIV YALE
摘要:Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar.

专利号:RU-2074180-C1
优先权日:1993-02-01
标 题:6(7)-halogen-1,3,3-trichloroisoindolenins as intermediate products for synthesis of dihalogen-substituted phthalocyanines or their complexes

专利号:EP-0485517-A1
优先权日:1989-08-11
标题 :Synthesis of glycosides having predetermined stereochemistry

专利号:CN-117567287-A
优先权日:2023-11-17
标题 :A kind of synthesis method of 2,4-dichloro-5-nitrobenzoic acid