CAS: 68892-41-1; N2-Isobutyryl-5'-O-(4,4'-Dimethoxytrityl)-2'-Deoxyguanosine

相似化合物

114745-26-5 81246-83-5 144089-96-3

上下游产品

CAS号68892-42-2 N2-异丁酰-2'-脱氧鸟甙 | CAS号40615-36-9 4,4'-二甲氧基三苯基氯甲烷 | CAS号961-07-9 2'-脱氧鸟苷 | CAS号82921-42-4 2'-deoxy-N2-iso... | CAS号132471-94-4 N2-isobutyryl-2... | CAS号64350-24-9 N2-异丁酰基鸟苷一水合物 | CAS号87865-78-9 3',5'-TIPS-N-IBU-鸟苷 | CAS号118-00-3 鸟苷 | CAS号74405-46-2 IBU-DMT-DEOXYGU... | CAS号68892-42-2 N2-异丁酰-2'-脱氧鸟甙 | CAS号81144-43-6 5'-O-(4,4'-二甲氧基... | CAS号84416-84-2 5'-O-(4,4'-DIME... | CAS号63660-23-1 N2-异丁酰基-3'-O-苯甲...

在 4-二甲氨基吡啶,Ammonium Hydroxide,Tea,1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 吡啶 作为反应溶剂,化学反应 6.0H,反应生成 N2-异丁酰-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧鸟苷
参考文献:Awasthi,S. K.; Khanna,V.; Watal,G.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1993,Vol. 32,# 9,P. 916-919
标题:Awasthi,S. K.; Khanna,V.; Watal,G.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1993,Vol. 32,# 9,P. 916-919

专利信息

专利号:US-2023212204-A1
优先权日:2020-01-16
标题:Reagents and their use for modular enantiodivergent synthesis of c-p bonds
发明人：XU DONGMIN; RIVAS-BASCÓN NAZARET; KNOUSE KYLE W; PADIAL NATALIA; ZHENG BIN; VANTOUROUT JULIEN; SCHMIDT MICHAEL; EASTGATE MARTIN D; BARAN PHI
权利人:BRISTOL MYERS SQUIBB CO; SCRIPPS RESEARCH INST
摘要:The disclosure describes chiral P(V)-based reagents and their uses for the modular, scalable, and stereospecific synthesis of chiral phosphines, phosphine oxides and particular oligonucleotides.

专利号:US-4849513-A
优先权日:1983-12-20
标 题 :Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-12337291-B2
优先权日:2017-09-11
标 题 :Guide RNA synthesis system and method
发明人：DABROWSKI PAUL; GERLINGHAUS FABIAN; KELSO REED; WALKER II JOHN ANDREW
权利人:SYNTHEGO CORP
摘要:The present invention provides improved automated systems and methods for synthesis of biopolymers including DNA and RNA. The automated systems and methods represent a number of improvements over existing systems for multiplex synthesis of biopolymers in a combinatorial fashion.

专利号:US-2013303745-A1
优先权日:2007-05-22
标 题:Synthesis of oligonucleotides
发明人：LANGE MEINOLF; HOHLFELD ANDREAS; SCHONBERGER ANDREAS; KIRCHHOFF CHRISTINA; GROSSEL OLAF
权利人:LANGE MEINOLF; HOHLFELD ANDREAS; SCHONBERGER ANDREAS; KIRCHHOFF CHRISTINA; GROSSEL OLAF
摘要:A method for preparing an oligonucleotide comprising the steps of synthesizing a phosphoramidite by reacting a hydroxyl-containing compound of formula (A) with a phosphitylating agent in the presence of an activator compound of formula (I), to prepare a phosphitylated compound, then coupling the phosphitylated compound without isolation with a second compound having the formula (A), wherein R 5 , R 3 , R 2 , B are independently selected, but have the same definition as above in the presence of an activator II selected from the group of imidazole, imidazolium salts, and mixtures thereof, which are improved activators over activators disclosed in related art.

专利号:US-5118800-A
优先权日:1983-12-20
标 题 :Oligonucleotides possessing a primary amino group in the terminal nucleotide
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5015733-A
优先权日:1983-12-20
标题 :Nucleosides possessing blocked aliphatic amino groups
发明人：SMITH LLOYD M; FUND STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieites may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.