CAS: 63039-46-3; (R)-2-((Tert-Butoxycarbonyl)Amino)Pent-4-Ynoic Acid

相似化合物

63039-48-5 23235-01-0 23235-03-2

上下游产品

N-(tert-butyloxycarbonyl) azide L-Propargylglycine tert-butyl dicarbonatedi-tert-butyl dicarbonate (R)-2-aminopent-4-ynoic acid methyl (2S)-2-(tert-butoxycarbonylamino)pent-4-ynoate (S)-2-tert-Butoxycarbonylamino-5-(2-fluoro-phenyl)-pent-4-ynoic acid H-[1,2,3]triazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid3-(1-benzyl-1H-[1,2,3]triazol-4-yl)-2-tert-butoxycarbonylamino-propionic acid (S)-2-((tert-butoxycarbonyl)amino)-4-pentynoic acid benzyl ester

Acetyloxy[[(1,1-Dimethylethoxy)Carbonyl]Amino]Acetic Acid Methyl Ester置于phosphate Buffer,锌体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 20.0H,反应生成 Boc-D-炔丙基甘氨酸
参考文献:Zinc Mediated Addition Of Active Halides To A Glycine Cation Equivalent: Synthesis Of N-Boc-L-Propargylglycine
标题:Zinc Mediated Addition Of Active Halides To A Glycine Cation Equivalent: Synthesis Of N-Boc-L-Propargylglycine
摘要:The Reaction Of Allylic,Benzylic And Propargylic Halides With Zinc In The Presence Of The Glycine Cation Equivalent,Methyl N-Boc-2-Acetoxyglycine,Affords Boc Protected Amino Acid Derivatives In High Yield. Resolution Of Methyl N-Boc-Propargylglycine With Alpha-Chymotrypsin Affords N-Boc-L-Propargylglycine In 99% E.E..
DOI:10.1016/s0040-4039(00)73067-X

专利信息

专利号:US-8722014-B2
优先权日:2009-05-01
标题 :1 H-[1, 2, 3] triazole substituted amino acids and uses thereof
发明人：MACH ROBERT H; MCCONATHY JONATHAN
权利人:MACH ROBERT H; MCCONATHY JONATHAN; UNIV WASHINGTON
摘要:Tracers for cationic amino acid transport systems and methods of synthesis are disclosed, including compounds comprising a 1H-[1,2,3]triazole moiety. Further disclosed are uses of the analogues, including in vivo imaging of tumors by Positron emission tomography (PET) or Single Photon Emission Computed Tomography (SPECT).