CAS: 596-03-2; 4',5'-Dibromo-3',6'-Dihydroxy-3H-Spiro[isobenzofuran-1,9'-Xanthen]-3-One

该化合物是一种有机染色剂,主要用作各种应用中的色素,包括塑料,墨水和涂层;它属于有一个或多个Azo染色族,其特点是有一个或多个Azo组(-N=N-),形成其充满活力的红色;该化合物以其在有机溶剂中的极佳溶解性而著称,使其适合用于非水系统;溶剂红色72显示良好的热稳定性和轻便性,这是维护最终产品中色完整性的重要特性;然而,它与许多Azo染色剂一样,由于潜在的毒性和降解后芳香性阿明的形成,可能会引起环境和健康问题;因此,其使用经常受到管制,应参考安全数据表,以确保适当的处理和处置;总的来说,溶剂红色72因其颜色特性而具有价值,但需要仔细考虑安全和环境影响.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

上下游产品

CAS号2321-07-5 荧光素 | CAS号2513-33-9 2',4'-二羟基-2-苯甲酰基苯甲酸 | CAS号108-46-3 间苯二酚 | CAS号85-44-9 苯酐 | CAS号25709-83-5 Spiroisobenzofu...

合成工艺路线路线简述

    📜Fluorescein Disodium Salt置于n-溴代丁二酰亚胺(Nbs),溶剂黄146体系中,化学反应 2.0H,以70%的收率获得产物二溴荧光素
    参考文献:新型β-环糊精-曙红结合物.
    标题:新型β-环糊精-曙红结合物.
    摘要:曙红b(eob)和曙红y(eoy),两种具有光敏能力的x吨染料衍生物是通过改进的合成途径高纯度制备的.使用偶联剂4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4,在稳定的酰胺键下,在温和的反应条件下,将染料接枝到6-单氨基-β-环糊精支架上.-甲基吗啉氯化物.通过1D和2D NMR光谱学和质谱法对分子共轭物在水介质中的溶解性进行了广泛的表征.初步的光谱研究表明,β-环糊精-Eoy共轭物既保留了荧光性质,又保留了未结合生色团的单线态氧的光生能力.相比之下,
    DOI:10.3762/bjoc.13.52

    海关参考信息

    专利信息


    专利号:US-2004267028-A1
    优先权日:2001-09-24
    标题 :Preparation and use of pyrrole derivatives for treating obesity
    发明人:SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
    权利人:SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
    摘要:This invention relates to pyrrole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

    专利号:US-7071207-B2
    优先权日:2001-09-24
    标题 :Preparation and use of 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives for treatment of obesity
    发明人:SMITH ROGER A; O'CONNOR STEPHEN J; WONG WAI C; CHOI SOONGYU; KLUENDER HAROLD C; FAN JIANMEI; ZHANG ZHONGHUA; LAVOIE RICO C; PODLOGAR BRENT L
    权利人:BAYER PHARMACEUTICALS CORP
    摘要:This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

    专利号:WO-2004058727-A1
    优先权日:2002-12-20
    标题 :Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity
    发明人:CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
    权利人:BAYER PHARMACEUTICALS CORP; CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
    摘要:This invention relates to substituted 3,5-dihydro-4H-imidazol-4-ones compounds which are useful in the treatment of obesity and obesity-related disorders, and as weight-loss and weight-control agents. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

    专利号:US-6960601-B2
    优先权日:2001-09-24
    标题 :Preparation and use of imidazole derivatives for treatment of obesity
    发明人:SMITH ROGER A; O'CONNOR STEPHEN J; WIRTZ STEPHAN-NICHOLAS; WONG WAI C; CHOI SOONGYU; KLUENDER HAROLD C E; SU NING; WANG GAN; ACHEBE FURAHI; YING SHIHONG
    权利人:BAYER PHARMACEUTICALS CORP
    摘要:This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

    专利号:US-10772990-B2
    优先权日:2014-04-01
    标题 :Tissue filler compositions and methods of use
    发明人:NIKOLIS ANDREAS; HERBERT LISE
    权利人:KLOX TECH INC
    摘要:The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Ali J, Irshad R, Li B, Tahir K, Ahmad A, Shakeel M, Khan NU, Khan ZUH. Synthesis and characterization of phytochemical fabricated zinc oxide nanoparticles with enhanced antibacterial and catalytic applications. J Photochem Photobiol B. 2018 May 9;183:349-356. doi: 10.1016/j.jphotobiol.2018.05.006. [Epub ahead of print] doi: 10.1016/j.micpath.2018.04.019. [Epub ahead of print] doi: 10.1161/STROKEAHA.118.020620. Epub 2018 Apr 6. doi: 10.1099/ijsem.0.002731. Epub 2018 Apr 5. doi: 10.3899/jrheum.170366. Epub 2018 Mar 15. Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens. Stroke. 2018 Mar;49(3):565-572. doi: 10.1161/STROKEAHA.117.019228. Epub 2018 Feb 19.
    8: Schellenberg J, Busse HJ, Hardt M, Schubert P, Wilke T, Kämpfer P, Glaeser SP. Proposal of Litorimonas haliclonae sp. nov., isolated from a marine sponge of the genus Haliclona. Int J Syst Evol Microbiol. 2018 Mar;68(3):835-843. doi: 10.1099/ijsem.0.002592. Epub 2018 Feb 1. doi: 10.1016/j.apcata.2017.09.021. Epub 2017 Sep 20.
    11: Guzmán-Dávalos L, Pradeep CK, Vrinda KB, Manoj Kumar A, Ramírez-Cruz V, Herrera M, Villalobos-Arámbula AR, Soytong K, Baroni TJ, Aime MC. A new stipitate species of Crepidotus from India and Thailand, with notes on other tropical species. Mycologia. 2017;109(5):804-814. doi: 10.1080/00275514.2017.1401834. Epub 2018 Jan 18. doi: 10.1039/c7nr08434j. Association Between Hyperacute Stage Blood Pressure Variability and Outcome in Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2018 Feb;49(2):348-354. doi: 10.1161/STROKEAHA.117.017701. Epub 2018 Jan 4. doi: 10.4253/wjge.v9.i12.571.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1007/s00216-004-2735-6
    摘要:Capitán-Vallvey LF, Guerrero EA, Merelo CB, Ramos MDF. A test strip for chloride analysis in environmental water. Analytical and Bioanalytical Chemistry. 2004 Aug 21;380(3):563–9. doi: 10.1007/s00216-004-2735-6.
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