CAS: 54110-25-7; Pyridine-2,6-Diylbis(Methylene) Bis(3,4,5-Trimethoxybenzoate)

该化合物是一种化学化合物,主要因其药理特性而得到承认,特别是血管病,被归类为衍生物,通过放松血管滑动肌肉影响血液流动;该化合物的运作机制可能涉及对氧化氮路径的调制,有助于其在血液循环受损条件下的治疗效果;Pirozadil已经研究其治疗心血管疾病的潜在应用,特别是改善周边循环;其化学结构包括功能组,这些功能组可提高其溶性和生物利用率,使其适合医药用途;许多药用活性物质,安全特征,剂量和潜在副作用都是其应用中的关键考虑因素;研究继续探索其作用和机制,以及它与其他药物的互动.

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    专利信息


    专利号:US-10925977-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
    发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
    权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
    摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

    专利号:US-10814013-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:US-2008107598-A1
    优先权日:2006-10-05
    标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

    专利号:AU-2007308022-B2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Masana L, Escobar A, Joven J, Solá R, Vilella E, Bargallo T, Turner PR. Treatment of diet-resistant polygenic hypercholesterolaemic patients with a new nicotinate derivative; in vivo and in vitro low density lipoprotein metabolic studies. J Clin Pharmacol. 1989 Mar;29(3):201-6. doi: 10.1002/j.1552-4604.1989.tb03313.x. 184(1):24-6. Spanish. 89(20):858-60. Spanish. 37(9):1069-71. 13(7):447-50. 87(3):259-64. Japanese. doi: 10.1254/fpj.87.259. 82(6):253-5. Spanish. 167(1):15-8. Spanish. 167(1):11-3. Spanish. 78(10):427-32. Spanish. 78(9):386-9. Spanish. 26(1):51-4. Spanish. 3(6):397-401. 6(1):41-50. Spanish. 31(4):395-401. doi: 10.1016/0021-9150(78)90134-x. 3(2):137-40. Spanish.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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