CAS: 521-35-7; Cannabinol

上下游产品

methyl magnesium iodide pyran-6-one1-hydroxy-9-methyl-3-pentyl-6H-dibenzopyran-6-one cannabinol tert-butyldimethylsilyl ether tetrahydr°Cannabinolcannabinolic acid

📜四氢大麻酚酸 反应生成 大麻酚
参考文献:Apparatus For Cannabinol Generation And Methods Of Using The Same
标题:Apparatus For Cannabinol Generation And Methods Of Using The Same
摘要:本公开揭示了从大麻组分中生产大麻酚的方法.本公开进一步提供了从大麻组分生产大麻酚的装置.

专利信息

专利号:US-2007287843-A1
优先权日:2004-04-07
标题 :Methods and Intermediates for the Synthesis of Delta-9 Tetrahydrocannabinol
发明人：CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
权利人:CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
摘要:Processes are disclosed for the synthesis of Delta-9 tetrahydrocannabinol which result in an improved Y-THC/Y-THC ratio, and intermediates are disclosed that may be used in the synthesis of Delta-9 tetrahydrocannabinol such that improved Y-THCIY-THC ratios are achieved. The intermediates may be cyclic compounds prepared from 2-Carene. There is also provided a scaleable process for the preparation of (+)-p-menth-2-ene-1,8-diol, another intermediate used in the synthesis of delta-9-tetrahydrocannibinol.

专利号:WO-2025217205-A1
优先权日:2024-04-08
标 题:Synthesis of (-)-trans-δ9-tetrahydrocannabivarin (δ9-thcv) and analogs thereof
发明人：HAGHDOOST MEHDI; ROBERTS MATTHEW; THOMAS BRIAN; DICKINSON LUKE; NIKITIN EDWARD
权利人:NALU BIO INC
摘要:A method is provided for the synthesis of (-)-trans-Δ9-tetrahydrocannabivarin (Δ9-THCV) and analogs thereof such that in the reaction product, the molar ratio of the Δ9 isomer to incidentally formed Δ8 isomers is greater than 4:1. Synthesis is carried out by combining a selected cannabinoid reactant, e.g., cannabidivarin (CBDV) or an analog thereof, with an acid in a solvent for the cannabinoid reactant, wherein the acid comprises (i) a Lewis acid having an acid softness index value in the range of -10 ΔG0 f, M n+ to ‑150 ΔG0 f, M n+, (ii) a Brønsted acid having a pKa in the range of -4.0 to +4.0, or (iii) a combination of (i) and (ii), under reaction conditions comprising a reaction temperature in the range of ‑0 °C to 25 °C and a reaction time in the range of 1 hour to 24 hours. The reaction is thereafter quenched with base and the solvent removed, wherein the crude reaction product so provided may be purified, e.g., chromatographically purified. Also provided is a method for synthesizing Δ9-THCV that further includes synthesis of the cannabinoid reactant. The invention additionally provides novel cannabinoid compositions that may be synthesized using the aforementioned methodology.

专利号:US-2024116890-A1
优先权日:2022-09-28
标 题 :Large scale synthesis of cannabinol
发明人：COLLINS ARIANNA C; CRUCES IVAN; RAY KYLE; CRUCES WESTLEY
权利人:COLORADO CHROMATOGRAPY LLC
摘要:Methods for producing cannabinol, cannabivarin, or derivatives thereof are disclosed. The methods disclosed herein can be employed for large scale synthesis or semi-synthesis of the compounds, including multi-kilogram quantities of the compounds.

专利号:US-2024228455-A1
优先权日:2021-04-27
标 题 :Synthesis of cbn and cbnv
发明人：KAVARANA MALCOLM J
权利人:TEEWINOT LIFE SCIENCES CORP
摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.

专利号:US-2020079715-A1
优先权日:2018-09-06
标题 :2-position modification for synthesis of resorcinol scaffolding
发明人：DAVIS ROBERT; BLACK JACOB; SMELTZER THOMAS; COLVIN SEAN
权利人:CANOPY HOLDINGS LLC
摘要:A resorcinol with modifications at the 2-position is provided. The reactant resorcinol may have a variety of functional groups at each of the 1, 3, and 5 position such as a hydroxide, a lower alkyl group, a phenyl, a substituted phenyl, a lower alkenyl, or a lower alkynyl sp 2 carbon group (e.g., substituted phenyl, vinyl), sp (e.g., alkyne), hydrogen. The resorcinol is modified at the 2-position with a nucleophile or an electrophile. The resulting resorcinol may serve as a stable intermediate for the synthesis of cannabinoid or cannabinoid derivatives.

专利号:US-11466283-B2
优先权日:2016-08-18
标 题:Plants and methods for increasing and decreasing synthesis of cannabinoids
发明人：ROSCOW ROBERT F
权利人:CANOPY GROWTH CORP
摘要:This disclosure relates to new plants and methods for increasing and decreasing synthesis of cannabinoids. The plants disclosed herein comprise unnatural ratios and concentrations of cannabinoids in plants of genus Cannabis . The methods disclosed herein comprise manipulating the biosynthetic pathway of cannabinoids to produce plants of genus Cannabis with unnatural ratios and concentrations of cannabinoids.