CAS: 50741-46-3; Ethyl Quinoline-3-Carboxylate

相似化合物

13669-42-6 6480-68-8 13669-51-7

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📜Ethyl 3-Acetoxy-3-(2-Azidophenyl)-2-Methylenepropanoate置于三苯基膦,Sodium Nitrite体系中,用 N,N-二甲基甲酰胺,甲苯 作为反应溶剂,化学反应 15.0H,反应生成 3-喹啉羧酸乙酯
参考文献:使用morita-baylis-hillman 2-叠氮基苯甲醛的乙酸酯合成2-烷氧基-3-氰基甲基喹啉和烷基喹啉-3-羧酸盐
标题:使用morita-baylis-hillman 2-叠氮基苯甲醛的乙酸酯合成2-烷氧基-3-氰基甲基喹啉和烷基喹啉-3-羧酸盐
摘要:一种简单的方法,可使用亚氨基膦烷介导的3-(2-叠氮基苯基)-2-氰基甲基丙酸酯和3-(2-叠氮基苯基)-2-亚胺基膦酸酯环化反应合成几种2-烷氧基-3-氰基甲基喹啉和烷基喹啉3-羧酸酯. ‐硝基甲基丙烯酸酯已开发出来.这些化合物分别是使用氰化钾或亚硝酸钠,分别从2-叠氮基苯甲醛的森田-贝利斯-希尔曼乙酸盐中获得的.j.杂环化学.(2011)
DOI:10.1002/jhet.667

专利信息

专利号:WO-2015198349-A1
优先权日:2014-06-25
标 题 :A one pot synthesis of 3-substituted quinoline carboxylates and its derivatives
发明人：GADAKH SUNITA KHANDERAO; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a one pot, simple, cost effective and industrially feasible catalytic synthesis of quinolines or substituted quinolines from anilines with yield >80% yield. The present invention also discloses a process for the synthesis of oxolinic acid using quinolines with yield > 45%.

专利号:US-4021429-A
优先权日:1975-07-24
标 题 :Synthesis of ethylenically unsaturated compounds from esters or amides
发明人：SCHROCK RICHARD ROYCE
权利人:DU PONT
摘要:Certain hydrocarbylidene-niobium or -tantalum complexes react with esters or N,N-disubstituted amides to produce ethylenically unsaturated compounds. Exemplary is the reaction of trineopentyl(neopentylidene)tantalum with ethyl acetate to produce 2-ethoxy-4,4-dimethyl-2-pentene:

专利号:US-10227355-B2
优先权日:2015-02-03
标题:Quinoline derivatives and preparation thereof
发明人：BALARAMAN EKAMBARAM; MIDYA SIBA PRASAD; JAISWAL GARIMA
权利人:COUNCIL SCIENT IND RES
摘要:The patent discloses novel quinoline derivatives of formula (I), (Formula should be inserted here) and process for preparing the same. The compounds of formula (I) can be further used for the synthesis of Inhibitors like Kinase Tyrosine Inhibitors.

专利号:CN-101418005-B
优先权日:2008-12-22
标 题:A new method for the synthesis of prulifloxacin

专利号:CN-101418005-A
优先权日:2008-12-22
标题:A new method for the synthesis of prulifloxacin

专利号:US-2008200475-A1
优先权日:2005-03-28
标题:4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2a , R x , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.