CAS: 4113-12-6; 1-(Hexadecyloxy)Hexadecane

该化合物是一种长链脂肪酒精,化学配方为C16H34O.其特征特征是其疏水碳氢化合物链,由16个碳原子和氢氧(OH)功能组组成.这种结构既具有亲脂性和体液性,又具有各种用途.六十二烷在室内温度下一般是一种白色,蜡状的固体,并有一个熔点,根据周围温度允许它是固体或半固体的.它溶解于水中,但在乙醇和乙醇等有机溶剂中是溶解的.这种化合物通常用于化妆品和个人护理产品,作为化剂,乳化剂和增厚剂.此外,它作为各种工业应用中的表面活性剂.其生物兼容性和低毒性使其适合用于用于用于皮肤接触的配方.

结构式图片

相似化合物

629-82-3 4542-57-8 2456-28-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

1-十六烷醇 1-Hexadecanol 36653-82-4
棕榈酸乙酯 Ethyl Palmitate 628-97-7

合成工艺路线路线简述

    📜1-十六烷醇置于tin (II) Sulfate体系中,化学反应生成 十六烷醚
    参考文献:Oddo,Gazzetta Chimica Italiana,1901,Vol. 31 I,P. 340
    标题:Oddo,Gazzetta Chimica Italiana,1901,Vol. 31 I,P. 340

    海关参考信息

    专利信息


    专利号:US-2012190064-A1
    优先权日:2004-10-01
    标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
    发明人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
    权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
    摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

    专利号:US-8932545-B2
    优先权日:2008-10-20
    标 题:Synthesis of metal compounds
    发明人:MEPSTED GARY OWEN; EWEKA EMMANUEL IMASUEN
    权利人:MEPSTED GARY OWEN; EWEKA EMMANUEL IMASUEN; QINETIQ LTD
    摘要:A method is provided for the synthesis of a mesoporous lithium transition metal compound, the method comprising the steps of (i) reacting a lithium salt with one or more transition metal salts in the presence of a surfactant, the surfactant being present in an amount sufficient to form a liquid crystal phase in the reaction mixture (ii) heating the reaction mixture so as to form a sol-gel and (iii) removing the surfactant to leave a mesoporous product. The mesoporous product can be an oxide, a phosphate, a borate or a silicate and optionally, an additional phosphate, borate or silicate reagent can be added at step (i). The reaction mixture can comprise an optional chelating agent and preferably, the reaction conditions at steps (i) and (ii) are controlled so as to prevent destabilization of the liquid crystal phase. The invention is particularly suitable for producing mesoporous lithium cobalt oxide and lithium iron phosphate. The method can be used to synthesize mesoporous lithium cobalt oxide having a specific surface area in excess of 10 m 2 /g, preferably 15 m 2 /g or more.

    专利号:US-4913852-A
    优先权日:1986-06-24
    标题 :Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with pregnane derivatives
    发明人:MILIONI CATHERINE; EFTHYIMIOPOULOS CONSTANTIN; KOCH BERNARD; JUNG LOUIS; JUNG JEAN
    权利人:MILIONI CATHERINE; EFTHYIMIOPOULOS CONSTANTIN; KOCH BERNARD; JUNG LOUIS; JUNG JEAN
    摘要:Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with derivatives of Δ-4-pregnene-3,20-dione or with derivatives of Δ-1,4-pregnadiene-3,20-dione of the general formulas (I), (II) and (III), having glucocorticoidal and anti-inflammatory properties have been prepared and tested. Pharmaceutical compositions, medicaments containing them as well as their applications are claimed, particularly in the cutaneous and ophthalmic fields. ##STR1##

    专利号:WO-2007094746-A1
    优先权日:2006-02-16
    标 题 :5,7-dimethyladamantane-1,3-dicarboxylic acid dialkyl esters, a method for the synthesis thereof and method for synthesising a 5,7-dimethyladamantane-1,3-dicarboxylic acid in the form of an intermediate product
    发明人:GOLOVKO LEONID VLADIMIROVICH; PILJAVSKY VOLODIMIR STEPANOVIC; BOYKO OLEKSANDR POLIKARPOVICH; KHILCHEVSKYY OLEKSANDR MIKOLAY; PETRENKO OLEKSANDR EVGRAFOVICH
    权利人:GOLOVKO LEONID VLADIMIROVICH; PILJAVSKY VOLODIMIR STEPANOVIC; BOYKO OLEKSANDR POLIKARPOVICH; KHILCHEVSKYY OLEKSANDR MIKOLAY; PETRENKO OLEKSANDR EVGRAFOVICH
    摘要:5,7-dimethyladamantane-1,3-dicarboxylic acid dialkyl esters of general formula (I), wherein R is C4 - C30 alkyl. Method for synthesis of said dialkyl esters consists in synthesising 5,7- dimethyladamantane-1,3-dicarboxylic acid chloride, alcoholising said chloride by aliphatic alcohol in a boiling benzene or toluene, removing a solvent and in purifying a target product. Method for synthesising 5,7-dimethyladamantane-1,3-dicarboxylic acid in the form of an intermediate product consists in synthesising perhydroacenaphthene by acenaphthene hydrogenation, isomerizating perhydroacenaphthene into 1,3-dimethyladamantane in the presence of AICI3, in synthesising 1,3-dimethyl-5,7-dibromoadamantane by two- stage bromation of 1,3-dimethyladamantane in such a way that a monobromoderivative thereof is obtained at the first stage, is subsequently converting it into 1,3-dimethyl-5,7-dibromoadamantane at the second stage and in carboxylating said compound by formic acid in the presence of 10-20% oleum.

    专利号:US-6869973-B2
    优先权日:2000-06-22
    标题:Nitrosated and nitrosylated taxanes, compositions and methods of use
    发明人:GARVEY DAVID S; LETTS L GORDON; LIN CHIA-EN; RICHARDSON STEWART K; WANG TIANSHENG
    权利人:NITROMED INC
    摘要:The present invention describes novel nitrosated and/or nitrosylated taxanes, and novel compositions comprising at least one nitrosated and/or nitrosylated taxane, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The present invention also provides novel compositions comprising at least one taxane and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The compounds and compositions of the present invention can also be bound to a matrix. The present invention also provides methods for treating or preventing cardiovascular diseases and disorders, autoimmune diseases, pathological conditions resulting from abnormal cell proliferation, polycystic kidney disease, inflammatory disease, preserving organs and/or tissues or to inhibit wound contraction, particularly the prophylactic and/or therapeutic treatment of restenosis, by administering nitrosated and/or nitrosylated taxane or parent taxanes in combination with nitric oxide donors that are capable of releasing nitric oxide or indirectly delivering or transferring nitric oxide to targeted sites under physiological conditions.

    专利号:US-2003203915-A1
    优先权日:2002-04-05
    标题 :Nitric oxide donors, compositions and methods of use related applications
    发明人:FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; LIN CHIA-EN; RANATUNGA RAMANI R; RICHARDSON STEWART K; WANG TIANSHENG; WANG WEIHENG; WEY SHIOW-JYI
    权利人:FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; LIN CHIA-EN; RANATUNGA RAMANI R; RICHARDSON STEWART K; WANG TIANSHENG; WANG WEIHENG; WEY SHIOW-JYI
    摘要:The invention describes novel nitric oxide donors and novel compositions comprising at least one nitric oxide donor. The invention also provides novel compositions comprising at least one nitric oxide donor, and, optionally, at least one therapeutic agent. The compounds and compositions of the invention can also be bound to a matrix. The invention also provides methods for treating cardiovascular diseases, for the inhibition of platelet aggregation and platelet adhesion caused by the exposure of blood to a medical device, for treating pathological conditions resulting from abnormal cell proliferation; transplantation rejections, autoimmune, inflammatory, proliferative, hyperproliferative, vascular diseases; for reducing scar tissue or for inhibiting wound contraction, particularly the prophylactic and/or therapeutic treatment of restenosis by administering the nitric oxide donor optionally in combination with at least one therapeutic agent. The invention also provides methods for treating inflammation, pain, fever, gastrointestinal disorders, respiratory disorders and sexual dysfunctions. The nitric oxide donors donate, transfer or release nitric oxide, and/or elevate endogenous levels of endothelium-derived relaxing factor, and/or stimulate endogenous synthesis of nitric oxide and/or are substrates for nitric oxide synthase and are capable of releasing nitric oxide or indirectly delivering or transferring nitric oxide to targeted sites under physiological conditions. The therapeutic agent can optionally be substituted with at least one NO and/or NO 2 group (i.e., nitrosylated and/or nitrosated). The invention also provides novel compositions and kits comprising at least one nitric oxide donor and/or at least one therapeutic agent.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/j.jcis.2011.06.053
    摘要:Gentile L, Mortensen K, Rossi CO, Olsson U, Ranieri GA. Multi-lamellar vesicle formation in a long-chain nonionic surfactant: C16E4/D2O system. J Colloid Interface Sci. 2011 Oct 01;362(1):1–4. doi: 10.1016/j.jcis.2011.06.053.
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