CAS: 34113-69-4; 4-Chloro-3-Hydroxybenzoic Acid

该化合物是一种卤化氢氧苯并呋喃衍生物,配有分子式C7H5ClO3.该化合物的特点是芳香环上既有氯和氢氧的功能组,有助于其在有机合成中的回活动和应用.该化合物是生产药品,农用化学品和特殊化学品的多用途中间体.用电子提纯的氯组增强了其稳定性,而氢氧组则允许进一步实现功能化.其晶体固体形式和定义明确的纯度使其适合在研究和工业过程中的精确应用.该化合物通常在标准实验室条件下处理,确保合成工作流程的一贯性能.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号931409-94-8 Benzoic acid, 4... | CAS号99-06-9 3-羟基苯甲酸 | CAS号2374-03-0 4-氨基-3-羟基苯甲酸 | CAS号7664-93-9 硫酸 | CAS号7782-50-5 氯气 | CAS号64-19-7 冰醋酸 | CAS号335013-90-6 4-氯-3-羟基-苯甲酸乙酯 | CAS号166272-81-7 3-羟基-4-氯苯甲酸甲酯 | CAS号116022-18-5 4-氯-3-甲氧基苯甲酸甲酯 | CAS号856165-82-7 4-氯-3-异丙氧基苯甲酸

合成工艺路线路线简述

  • 合成目标产物 4-Chloro-3-Hydroxybenzoic Acid 主要起始原料 Ethanamine, N-[(3,5-Dichlorophenyl)Methylene]-2,2-Diethoxy-
  • (文献来源)合成步骤主要原料 Ethanamine, N-[(3,5-Dichlorophenyl)Methylene]-2,2-Diethoxy-
间羟基苯甲酸置于二硫化碳,氯,Iron(II) Chloride体系中,化学反应生成 4-氯-3-羟基苯甲酸
参考文献:De74493
标题:De74493

海关参考信息

专利信息


专利号:US-8163773-B2
优先权日:2005-07-11
标题 :Organic compounds
发明人:BREITENSTEIN WERNER; ERHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; MASUYA KEIICHI; KONISHI KAZUHIDE; YOKOKAWA FUMIAKI; KANAZAWA TAKANORI; JACOBY EDGAR; MARZINZIK ANDREAS; GROSCHE PHILIPP; KAWAKAMI SHIMPEI
权利人:BREITENSTEIN WERNER; ERHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; MASUYA KEIICHI; KONISHI KAZUHIDE; YOKOKAWA FUMIAKI; KANAZAWA TAKANORI; JACOBY EDGAR; MARZINZIK ANDREAS; GROSCHE PHILIPP; KAWAKAMI SHIMPEI; NOVARTIS AG
摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula I wherein R1, R2, T, R3 and R4 are as defined in the specification.

专利号:US-7807709-B2
优先权日:2005-03-23
标题 :Organic compounds
发明人:EHRHARDT CLAUS; IRIE OSAMU; LORTHIOIS EDWIGE LILIANE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER
权利人:NOVARTIS AG
摘要:The invention relates to the use of (3,4-di-, 3,3,4-tri, 3,4,4-tri- or 3,3,4,4-tetra-)substituted pyrrolidine compounds for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; compounds that are part of a subclass of these substituted pyrrolidine compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; new compounds that are part of a subclass of these substituted pyrrolidine compounds; pharmaceutical formulations comprising said substituted pyrrolidine compounds, and/or a method of treatment comprising administering said substituted pyrrolidine compounds, a method for the manufacture especially of said new substituted pyrrolidine compounds, as well as novel intermediates, starting materials and/or partial steps for their synthesis.

专利号:EP-2968667-A1
优先权日:2013-03-14
标题:Peg-based adhesive phenylic derivatives and methods of synthesis and use

专利号:US-2016032047-A1
优先权日:2013-03-14
标题 :Peg-based adhesive phenylic derivatives and methods of synthesis and use

专利号:CA-2905840-A1
优先权日:2013-03-14
标题 :Peg-based adhesive phenylic derivatives and methods of synthesis and use

专利号:WO-2014158288-A1
优先权日:2013-03-14
标 题:Peg-based adhesive phenylic derivatives and methods of synthesis and use
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