CAS: 3055-96-7; Hexaethylene Glycol Monododecyl Ether

该化合物是一种非离子表面活性剂,由六乙基羟基链和多丁基氢脱氧(C12)烷基化合物组成,这种结构提供了平衡的两栖性,使其在水体系统中能够有效地溶解缺水化合物,其主要优势包括:在广泛的pH值范围内具有高度稳定性,泡沫特性低,与其他表面活性剂非常相容.该化合物广泛用于工业和实验室应用,如乳化,湿化和散射过程.其相对较长的乙基氧化乙烷链在保持温度的同时会提高水溶性,使其适合低刺激性制剂.该产品在高浓度和低浓度应用中都因其可靠性而得到重视.

结构式图片

相似化合物

3055-99-0 19327-39-0 5274-63-5

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

3-十二烷醇 2-[2-(2-Dodecyloxy-Ethoxy)-Ethoxy]-Ethanol 3055-94-5
1-[2-[2-(2-Chloroethoxy)Ethoxy]Ethoxy]Dodecane 17464-53-8

合成工艺路线路线简述

    📜1,3,6,9-Tetraoxa-2-Thiacycloundecane-2,2-Dioxide置于sodium Hydride体系中,用 四氢呋喃 作为反应溶剂,化学反应 10.75H,反应生成 六乙二醇单十二醚
    参考文献:单分散九聚乙二醇十二烷基醇单醚及其硫酸盐的制备方法和应用
    标题:单分散九聚乙二醇十二烷基醇单醚及其硫酸盐的制备方法和应用
    摘要:本发明公开了一种单分散九聚乙二醇十二烷基醇单醚及其硫酸盐的制备方法和应用,属于医药化工领域.从十二烷基醇出发,首先在碱的作用下通过与九聚乙二醇环硫酸酯的一次开环反应或通过与共含有九个乙二醇单元的多个寡聚乙二醇环硫酸酯的多次开环反应得到九聚乙二醇十二烷基醇单醚的硫酸盐;然后在硫酸的作用下水解得到九聚乙二醇十二烷基醇单醚.该方法可用于单分散聚乙二醇的长链烷基单醚及其硫酸盐的制备中.本发明以单一分子量聚乙二醇环硫酸酯为原料实现了六聚以上乙二醇的烷基醇单醚的高效合成,合成中没有用保护基,步骤简便,适于工业化生产,得到的产品相对于现有制备的聚桂醇具有明显的优势.

    海关参考信息

    专利信息


    专利号:US-2012190064-A1
    优先权日:2004-10-01
    标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
    发明人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
    权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
    摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

    专利号:US-11618777-B2
    优先权日:2015-07-31
    标 题 :Method of manufacturing membrane protein and utilization thereof
    发明人:YOKOYAMA SHIGEYUKI; SHINODA TAKEHIRO; ITO KAORI; NOMURA NAOKO; KATSURA YOSHIKO; SOMEYA TOMOMI; SHIROUZU MIKAKO; HORI TETSUYA; NAKAMURA YOSHIHIRO; TANABE HIROAKI
    权利人:YOKOYAMA SHIGEYUKI
    摘要:In order to provide a membrane protein production method which does not require the step of solubilizing a membrane protein and which allows the membrane protein having an excellent quality to be obtained with a high yield, a method in accordance with an embodiment of the present invention includes: a step (a) of preparing a reaction solution for cell-free protein synthesis, the reaction solution containing (i) a template nucleic acid which encodes the membrane protein, (ii) a lipid, and (iii) a detergent which is contained at a concentration equal to or higher than a critical micelle concentration; and a step (b) of synthesizing the membrane protein while the concentration of the detergent in the reaction solution is maintained at a concentration equal to or higher than a critical micelle concentration.

    专利号:US-2004220137-A1
    优先权日:2001-07-07
    标 题:Cosmetic and dermatological preparations containing osmolytes for the treatment of and active prevention of dry skin and of other negative alterations in the physiological homeostasis of healthy skin
    发明人:SAUERMANN GERHARD
    摘要:Use of n a) one or more compounds from the group of osmolytes or precursors and derivatives thereof, n b) optionally one or more compounds from the group of electrolytes and n c) optionally one or more compounds from the group formed by polyols and urea, n in preparations (cosmetics, dermatological preparations) to be applied topically for the treatment and active prevention of dry skin and for strengthening the barrier function of the skin, and for the treatment, care and prophylaxis of sensitive skin and/or for the treatment and prophylaxis of the symptoms of a negative change in the physiological homeostasis of healthy skin, in particular deficient, sensitive or hypoactive skin conditions or n deficient, sensitive or hypoactive conditions of skin appendages, inflamed skin conditions, and of atopic eczema, polymorphous photodermatosis, psoriasis, vitiligo, n sensitive, itching or irritated skin, n changes in normal lipid peroxidation, n a change in the ceramide, lipid and energy metabolism of healthy skin, n a change in the physiological transepidermal water loss, n a reduction in skin hydration and decrease in the moisture content of the skin, n change in the natural moisturizing factor content, n reduction in cell-cell communication, n deficiency symptoms of intracellular DNA synthesis, n DNA damage and reduction in endogenous DNA repair mechanisms, n activation of metalloproteinases and/or other proteases or inhibition of the corresponding endogenous DNA repair mechanisms, n deviations from the normal post-translational modifications of connective tissue constituents, n changes in the normal hyaluronic acid and glucosaminoglycan content of healthy skin, dandruff formation by the hair, flaking of the scalp and skin ageing.

    专利号:US-11744248-B2
    优先权日:2017-08-20
    标 题:Disinfectant composition for control of clostridium difficile spore
    发明人:SMYTH BRUCE; BRALKOWSKI MICHAEL
    权利人:SMYTH BRUCE; BRALKOWSKI MICHAEL; ENVIRO SPECIALTY CHEMICALS INC
    摘要:A composition and method for inducing and inflicting damage to cell membranes of microorganism by inducing changes in membrane permeability caused by polycation-induced membrane pores. The control of Clostridium difficile spores with an efficacy of 99.99% on hard surfaces is provided. The invention includes the application of an evaporation-induced self-assembly, surfactant-mediated synthesis or self-condensing polymer, which forms a film which is both flexible on the surface as a nano-polymeric coating and with refractive index yielding a transparent coating. The polymeric matrix includes various biocidal polymeric cationic quaternary salts, one being a silyl quaternary having a kinetic zeta potential to disrupt bacterial spores functions. The polymeric matrix consist of multiple small molecule biocides as well as polymerics biocide combinations not otherwise seen to develop an surface topography of peaks and troughs in the nano range to resist bacterial adhesion factors and subsequent biofilm formation. The surfactants induce self-assembly film topography.

    专利号:US-2009209032-A1
    优先权日:2004-10-01
    标 题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules

    专利号:EP-1848812-A2
    优先权日:2004-10-01
    标题:Feeding buffers, systems, and methods for in vitro synthesis of biomolecules

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: A C Donegan, Et Al. Solubilization Kinetics Of N-Alkanes By A Non-Ionic Surfactant. J Pharm Pharmacol. 1987 Jan;39(1):45-7.
    [参考文献]: A Goto, Et Al. Gel Filtration Of Solubilized Systems. Vii. Temperature Effect On The Solubilization Of Ethylparaben In Hexaoxyethylene Lauryl Ether Micelles. Chem Pharm Bull (Tokyo). 1984 Aug;32(8):2905-9.
    [参考文献]: Cristóbal Carnero Ruiz, Et Al. Analysis Of The Photophysical Behavior And Rotational-Relaxation Dynamics Of Coumarin 6 In Nonionic Micellar Environments: The Effect Of Temperature. Molecules. 2015 Oct 23;20(10):19343-60.
    [参考文献]: G Calvin, Et Al. Absorption And Elimination Of A Branched-Chain Alkylpolyethoxylate Surfactant In Rats. Toxicol Lett. 1983 Sep;18(3):351-7.
    [参考文献]: Joseph Chamieh, Et Al. Size Characterization Of Commercial Micelles And Microemulsions By Taylor Dispersion Analysis. Int J Pharm. 2015 Aug 15;492(1-2):46-54.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 31(Suppl. 2):169-244, 2012
    参考文献:10.1021/jp7110742
    摘要:Miyake M, Asano A, Einaga Y. Size change of the wormlike micelles of pentaoxyethylene, hexaoxyethylene, and heptaoxyethylene dodecyl ethers with uptake of n-dodecane. J Phys Chem B. 2008 Apr 17;112(15):4648–55. doi: 10.1021/jp7110742.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知