CAS: 226903-07-7; 1-Cyclopropyl-6-Hydroxy-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic Acid
该化合物是一种众所周知的氟丙酮抗生素的结构性类比,其特征是将六点的氟原子替换为六点的氢氧原子,这可能会影响其药理特性.修改可能会改变细菌DNAgyrase和TOpo异构体ase IV的结合性,可能会影响抗微生物活动和抗药性特征.这一复合物对于研究应用具有兴趣,特别是在研究氟丙酮类的结构-活动关系方面,其合成和评价可以提供在应对抗药机制的同时优化抗菌功效的洞见.对于分析和调查来说,它可以作为抗微生物发育的宝贵参考材料.
- 英文名称1-Cyclopropyl-6-Hydroxy-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic Acid
- 中文名称环丙沙星杂质F
- IUPAC名称1-cyclopropyl-6-hydroxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
- 其它别名Ciprofloxacin Impurity 6(Ciprofloxacin Ep Impurity F); 1-Cyclopropyl-1,4-Dihydro-6-Hydroxy-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid; Ciprofloxacin Impurity-F(Ep); Ciprofloxacin Ep Impurity F; Ciprofloxacin Ep Imp F; Ciprofloxacin Impurity 5/ciprofloxacin Ep Impurity F/6-Hydroxy-6-Defluoro Ciprofloxacin/1-Cyclopropyl-6-Hydroxy-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid; 1-Cyclopropyl-6-Hydroxy-4-Oxo-7-Piperazin-1-Ylquinoline-3-Carboxylic Acid; Ciprofloxacin Impurity F Hcl
- CAS编号226903-07-7
- MFCD编号:MFCD18379447
- FDA UNII编号:MM5YD792QW
- 分子式:C17H19N3O4分子量:329.36
- 产品CID: 1165554
- 产品分类Chemistry → Organic Building Blocks → Carboxylic Acids | Quinolines | Piperazines | Alcohols | Ketones | Aromatic Heterocycles
物理性质
MSDS等安全信息
上下游产品
ciprofloxacin合成工艺路线路线简述
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合成参考文献
参考文献:10.1007/s11356-017-0404-5
摘要:Villegas-Guzman P, Hofer F, Silva-Agredo J, Torres-Palma RA. Role of sulfate, chloride, and nitrate anions on the degradation of fluoroquinolone antibiotics by photoelectro-Fenton. Environmental Science and Pollution Research. 2017 Oct 10;24(36):28175–89. doi: 10.1007/s11356-017-0404-5.
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