CAS: 215054-80-1; L-Allysine Ethylene Acetal
化学文摘社编号215054-80-1,化学化合物,其独特的结构,包括二氧烷环和氨基酸混合物.该化合物通常具有与环状醚和氨基酸相关的特性,可影响其反应性和溶性.二氧烷环的存在有助于其稳定性和形成氢联结的潜力,而氨基酸结构允许氨基酸的典型相互作用,如形成丙酸联结.该化合物可能在不同领域,包括医药化学和材料科学领域都感兴趣,因为其潜在的生物活动和作为更复杂分子的建筑块的能力.其立体化学学学,如(S)-称,可以提出能够影响其生物互动和特性的具体空间安排.
- 英文名称L-Allysine Ethylene Acetal
- 中文名称L-醛赖氨酸乙烯乙缩醛
- IUPAC名称(S)-2-amino-5-(1,3-dioxolan-2-yl)pentanoic acid
- 其它别名L-Allysine Ethylene Acetal ; 1,3-Dioxolane-2-Pentanoicacid,A-Amino-,(As)- ; (S)-Alpha-Amino-1,3-Dioxolane-2-Pentanoic Acid ; Rqulwpsgqyzrei-Lurjtmiesa-N ; (S)-2-Amino-5-(1,3-Dioxolan-2-yl)Pentanoic Acid ; 5-(1,3-Dioxolan-2-yl)-(S)-2-Amino-Pentanoic Acid ;
- CAS编号215054-80-1
- MFCD编号:MFCD07778443
- 分子式:C8H15NO4分子量:189.21
- 产品CID: 1117534
- 产品分类有机原料→生命科学→氨基酸及其衍生物→赖氨酸及其衍生物
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- 合成目标产物 (S)-2-Amino-5-(1,3-Dioxolan-2-yl)-Pentanoic Acid 主要起始原料 1,3-Dioxolane-2-Pentanoic Acid, α-(Benzoylamino)-
- (文献来源)合成步骤主要原料 1,3-Dioxolane-2-Pentanoic Acid, α-(Benzoylamino)-
📜5-(1,3-Dioxolan-2-yl)-2-Oxo-Pentanoic Acid 以86-97.5的收率获得(S)-2-氨基-5-(1,3-二氧戊环-2-基)戊酸
参考文献:Biomolecular Engineering. 2001,17,167-182
标题:Biomolecular Engineering. 2001,17,167-182
海关参考信息
- 2905121000-正丙醇
2905130000-正丁醇
2905310000-1,2-乙二醇
2909110000-乙醚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2024103123-A1
优先权日:2022-11-17
标题 :The synthesis of omapatrilat
发明人：VITALE ROMINA; MARTIN VINCENT ALEXANDRE; FABER WIJNAND; SOMMER ROMAN
权利人:ENDOTHELIUM SCANNING NANOTECHNOLOGY LTD
摘要:Described herein are improved methods of making Compound 1 (4S,7S,10aS)-4-((S)-2- mercapto-3-phenylpropanamido)-5-oxooctahydro-7H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid, or Omapatrilat, and purified Omapatrilat obtained from the improved methods.
专利号:US-2018273571-A1
优先权日:2015-01-08
标 题 :Concise synthesis of urea derivatives of amphotericin b
专利号:EP-4619408-A1
优先权日:2022-11-17
标题 :The synthesis of omapatrilat
专利号:AU-2016205187-A1
优先权日:2015-01-08
标题 :Concise synthesis of urea derivatives of amphotericin B
专利号:US-7671231-B2
优先权日:2006-01-18
标 题 :Process for making amino acids
发明人：LLOYD MICHAEL C; DAUGS EDWARD D; RAND CYNTHIA L; PENG WEI-JUN
权利人:LLOYD MICHAEL C; DAUGS EDWARD D; RAND CYNTHIA L; PENG WEI-JUN
摘要:A process for making an amino acid by the steps of: (a) contacting a compound of formula I n nwith a hydroformylation catalyst and synthesis gas to produce a mixture of aldehyde compounds comprising the formulas IIa, IIb and IIc;n n n n n n n n n n n (b) reacting the mixture of aldehyde compounds from step (a) to produce a mixture of derivative compounds; n (c) contacting the mixture of derivative compounds from step (b) with an enantioselective hydrolase enzyme in the presence of water to produce an L-amino acid having the formula IV; n n n n n n n n n n n n (d) isolating the amino acid having the formula IV in substantially pure form,n nwherein in formulas I, IIa, IIb, IIc, IIIa, IIIb, IIIc and IV, R is H, alkyl or aryl and R 1 and R 2 are the same or different alkyl groups and wherein R 1 and R 2 may be fused.
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主要参考文献
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.合成参考文献
参考文献:10.1007/3418_2019_31
摘要:Basu D, Achanta S, Kumar NU, Rehani RB, Bandichhor R. Application of Organometallic Catalysts in API Synthesis. 2019. In: Topics in Organometallic Chemistry.
参考文献:10.1007/978-3-031-52858-3_4
参考文献:10.1007/978-3-031-58819-8_26
摘要:Khalil Y, Clayton PT, Mills PB. α-Aminoadipic Semialdehyde and 6-Oxo-pipecolic Acid. 2024. In: Laboratory Guide to the Methods in Biochemical Genetics.
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