CAS: 21324-39-0; Sodium Hexafluorophosphate

专利信息

专利号:US-6846922-B1
优先权日:1998-06-02
标题 :Activators for oligonucleotide synthesis
发明人：MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T
权利人:ISIS PHARMACEUTICALS INC
摘要:The present invention relates to improved methods for the preparation of nucleoside phosphoramidites and oligonucleotides. In one aspect, the methods of the invention are used to prepare phosphitylating reagents using pyridinium salts as activators. In a further aspect, the methods of the invention are used to prepare internucleoside linkages using activators which include at least one pyridinium salt and at least one substituted imidazole. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having 2′-substituents using imidazolium or benzimidazolium salts as an activator. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having bioreversible protecting group that confers enhanced chemical and biophysical properties, without exocyclic amine protection, using imidazolium or benzimidazolium salts as an activator.

专利号:CN-114349936-A
优先权日:2021-12-20
标题 :Synthesis method of a class of quinone-nitrogen heterocyclic polymers and their application in secondary batteries

专利号:CN-115285965-B
优先权日:2022-08-22
标 题 :A kind of synthesis method of sodium hexafluorophosphate