CAS: 17289-25-7; (1-Methyl-1H-Imidazol-4-yl)Methanol
该化合物是一种多用途有机化合物,具有独一无二的1H-imidazol-4-yl组,具有高纯度和稳定性,在有机合成中可理想地广泛应用,包括混合循环化合物的制备.该化合物与各种试剂和催化剂非常相容,有利于高产量的合成转化.
- 英文名称(1-Methyl-1H-Imidazol-4-yl)Methanol
- 中文名称(1-甲基-1H-咪唑-4-基)甲醇
- IUPAC名称(1-methyl-1H-imidazol-4-yl)methanol
- 其它别名Imidazole-4-methanol,1-methyl- (8CI); 1-Methyl-1H-imidazol-4-ylmethanol; 1-Methyl-4-hydroxymethylimidazole; 1-Methyl-4-imidazolemethanol; 4-(Hydroxymethyl)-1-methylimidazole
- CAS编号17289-25-7
- MFCD编号:MFCD06738905
- EINECS号:835-195-9
- 分子式:C5H8N2O分子量:112.13
- 产品CID: 884488
- 产品分类医药中间体
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号41716-18-1 1-甲基-4-咪唑甲酸 | CAS号822-55-9 4-(羟甲基)咪唑 | CAS号17289-30-4 5-氯甲基-1-甲基-1H-咪唑盐酸盐 | CAS号17289-26-8 1-甲基-1H-咪唑-4-甲醛 | CAS号96831-65-1 (1-甲基-1H-咪唑-4-基... | CAS号6338-45-0 1,4-二甲基-1H-咪唑合成工艺路线路线简述
- 合成目标产物 (1-Methyl-1H-Imidazol-4-yl)Methanol 主要起始原料 1-Methyl-1H-Imidazole-4-Carboxylic Acid
- (文献来源)合成步骤主要原料 1-Methyl-1H-Imidazole-4-Carboxylic Acid
📜在 水,三氟乙酸体系中,化学反应 2.0H,反应生成(1-甲基-1H-咪唑-4-基)甲醇
参考文献:通过钯催化的2-碘代咪唑的交叉偶联反应,新的不对称合成蛋白质法呢基转移酶抑制剂†
标题:通过钯催化的2-碘代咪唑的交叉偶联反应,新的不对称合成蛋白质法呢基转移酶抑制剂†
摘要:钯 的催化交叉偶联反应 2-碘咪唑 已经研究合成 咪唑含蛋白质法呢基转移酶抑制剂.铃木偶联反应被证明非常有效地在咪唑环的2位引入官能化的烷基链,并且通过交叉复分解反应实现了所需烯基硼酸酯的新合成.烯丙基琥珀酸衍生物的不对称合成使我们能够通过suzuki偶联合成手性蛋白法呢基转移酶抑制剂,并确定我们抑制剂的立体化学对酶活性的影响.
Doi:10.1039/b902601K
海关参考信息
- 2905110000-甲醇
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9376461-B2
优先权日:2011-06-06
标 题:Non-enzymatic synthesis of O-acetyl-ADP-ribose and analogues thereof
发明人：KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B
权利人:KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B; GLAXOSMITHKLINE LLC
摘要:Provided herein is a simple, one-step, non-enzymatic synthesis of O-Acetyl-ADP-ribose (OAADPR) from NAD and sodium acetate in acetic acid. The extension of this reaction to other carboxylic acids, demonstrates that the reaction between NAD, and NAD analogs produces mixtures of the corresponding 2′- and 3′-carboxylic esters. Included are O-carboxyl-ADP-ribose compounds and corresponding methods of synthesis (e.g., O-propionyl-ADP-ribose, O-succinyl-ADP-ribose, O-malonyl-ADP-ribose), as well as non-adenosine nucleoside compounds.
专利号:US-2010286211-A1
优先权日:2004-10-08
标题:Oxazolidinone derivatives as antimicrobials
发明人：DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
权利人:DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
专利号:US-2015218202-A1
优先权日:2011-06-06
标 题:Non-enzymatic synthesis of o-acetyl-adp-ribose and analogues thereof
