CAS: 133099-04-4; Darifenacin

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CAS号133033-99-5 氧化达非那新杂质 | CAS号133099-07-7 氢溴酸达非那新 | CAS号127264-14-6 5-(2-溴乙基)-2,3-二氢苯并呋喃 | CAS号134002-25-8 3-(S)-(1-氨基甲酰-1... | CAS号1072227-73-6 2,2-diphenyl-2-... | CAS号1189753-52-3 (S)-2,2-dipheny... | CAS号133099-11-3 (S)-alpha,alpha... | CAS号90843-31-5 5-乙酰基-2,3-二氢苯并[b]呋喃 | CAS号151427-19-9 2-溴-1-(2,3-二氢-1... | CAS号133099-07-7 氢溴酸达非那新

氢溴酸达非那新置于sodium Hydroxide体系中,用 水 用作溶剂,化学反应生成达非那新
参考文献:Novel Polymorphs Of Darifenacin Free Base And Its Hydrobromide Salt
标题:Novel Polymorphs Of Darifenacin Free Base And Its Hydrobromide Salt
摘要:本发明提供了一种新颖且稳定的达瑞那新无水基固态非晶态形式,其制备方法,制药组合物和治疗方法.本发明还提供了一种新颖且稳定的达瑞那新盐酸盐多晶形式,其制备方法,制药组合物和治疗方法.

专利信息

专利号:WO-2009153649-A1
优先权日:2008-06-19
标 题:Process for preparing 3-substituted pyrrolidine compounds
发明人：SOLDEVILLA MADRID NURIA
权利人:MEDICHEM SA; SOLDEVILLA MADRID NURIA
摘要:Disclosed is a process for preparing 3 -substituted pyrrolidine compounds of formula (VII) or salts thereof, wherein R1 is described herein, which are intermediate compounds useful for the synthesis of darifenacin which is indicated for the treatment of overactive bladder with symptoms of urge, urinary incontinence, and the like, and pharmaceutically acceptable salts thereof. Also disclosed is a process for preparing darifenacin and pharmaceutically acceptable salts thereof.

专利号:US-9982006-B2
优先权日:2014-08-21
标题:2′-chloro aminopyrimidinone and pyrimidine dione nucleosides
发明人：CLARKE MICHAEL O'NEIL HANRAHAN; MACKMAN RICHARD L; SIEGEL DUSTIN
权利人:GILEAD SCIENCES INC
摘要:Provided herein are formulations, methods and substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of substituted 2′-chloro aminopyrimidinone and pyrimidine dione compounds.

专利号:EP-4630405-A1
优先权日:2022-12-06
标题 :Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

专利号:WO-2024123815-A1
优先权日:2022-12-06
标 题:Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人：SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

专利号:CN-114126619-B
优先权日:2019-05-09
标 题:Compounds used in the synthesis of peptide mimetics