CAS: 861533-46-2; 3,3'-Dihydroxy-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid

• 英文名称3,3'-Dihydroxy-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid
• 中文名称3,3'-二羟基-[1,1'-联苯]-4,4'-二羧酸
• IUPAC名称3,3'-dihydroxy-[1,1'-biphenyl]-4,4'-dicarboxylic acid
• 其它别名3,3'-Dihydroxy-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid; [1,1'-Biphenyl]-4,4'-Dicarboxylic Acid, 3,3'-Dihydroxy-; 4,4'-Bisalicylic Acid; 3,3′-Dihydroxy-4,4′-Biphenyldicarboxylic Acid; 4-(4-Carboxy-3-Hydroxyphenyl)-2-Hydroxybenzoic Acid
• CAS编号861533-46-2
• MFCD编号:MFCD24387008
• 分子式:C14H10O6
• 分子量:274.23
• 产品CID: 1862380
• 产品分类有机原料→材料科学→MOF有机配体→羧酸MOF配体

• 相似结构搜索
• InChIKey: HVMTVUVEDJACFQ-UHFFFAOYSA-N
• InChI=1S/C14H10O6/c15-11-5-7(1-3-9(11)13(17)18)8-2-4-10(14(19)20)12(16)6-8/h1-6,15-16H,(H,17,18)(H,19,20)…
• 计算化学: 氢键受体数4.0氢键供体数4.0可旋转键数3.0

相似化合物

物理性质

• 熔点318 °C
• 沸点564.4±50.0 °C at 760 mmHg
• 密度1.552±0.06 g/cm3(预测)
• pKa:2.56±0.10(预测)
• PSA:115.06
• LogP:2.1612
• 外观形态白色至淡棕色固体
• 储存条件2-8°C

MSDS等安全信息

• GHS符号GHS07
• 警示词Warning
• 危险描述H302-H315-H319-H335
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

上下游产品

合成工艺路线路线简述

• 合成目标产物 3,3'-Dihydroxy-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid 主要起始原料 Methyl 4-Bromo-2-Hydroxybenzoate
• 148490-98-6 = 861533-46-2
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 24 H,50 °C; 50 °C -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
  标题:Novel Ni-Irmof-74 Postsynthetically Functionalized For H2 Storage Applications
  作者:Montes-Andres,Helena; Et Al
  参考文献:Journal Of Physical Chemistry C 日期:2018 卷标:122(49) 页码:28123-28132]
  
  = 861533-46-2
  反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate; 24 H,50 °C1.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 24 H,50 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 2,Rt
  标题:Large-Pore Apertures In A Series Of Metal-Organic Frameworks
  作者:Deng,Hexiang; Et Al
  参考文献:Science (Washington 日期:2012 卷标:336(6084) 页码:1018-1023]
  
  148490-97-5 = 861533-46-2
  反应条件:1.1 Catalysts: Copper; 210 - 220 °C2.1 Reagents: Potassium Hydroxide,Hydrochloric Acid Solvents: Methanol; 65 °C3.1 Reagents: Hydrogen Bromide Solvents: Acetic Acid; 8 H,127 °C
  标题:Three 3D Lanthanide-Organic Frameworks With Sra Topology: Syntheses,Structures,Luminescence And Magnetic Properties
  作者:Liu,Xiaolan; Et Al
  参考文献:Crystengcomm 日期:2014 卷标:16(13) 页码:2779-2787]
  
  18179-39-0 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Acetonitrile; Overnight,Rt -> 80 °C2.1 Reagents: Cesium Fluoride Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 14 H,90 °C3.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate; 24 H,Rt -> 50 °C3.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Pore-Engineered Metal-Organic Frameworks With Excellent Adsorption Of Water And Fluorocarbon Refrigerant For Cooling Applications
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2017 卷标:139(31) 页码:10601-10604]
  
  16870-28-3 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Acetone; 8 H,Reflux2.1 Reagents: Copper; 3 H,210 - 220 °C3.1 Reagents: Pyridinium Chloride; 3 H,210 - 220 °C; 220 °C -> 100 °C3.2 Reagents: Hydrochloric Acid Solvents: Water; 100 °C -> Rt
  标题:Synthesis And Characterization Of 3,3'-Dihydroxy-1,1'-Biphenyl-4,4'-Dicarboxylic Acid
  作者:Zhou,Jun; Et Al
  参考文献:Nanjing Gongye Daxue Xuebao 日期:2007 卷标:29(1) 页码:16-18]
  
  16870-28-3 = 861533-46-2
  反应条件:1.1 80 °C2.1 Catalysts: Copper; 210 - 220 °C3.1 Reagents: Potassium Hydroxide,Hydrochloric Acid Solvents: Methanol; 65 °C4.1 Reagents: Hydrogen Bromide Solvents: Acetic Acid; 8 H,127 °C
  标题:Three 3D Lanthanide-Organic Frameworks With Sra Topology: Syntheses,Structures,Luminescence And Magnetic Properties
  作者:Liu,Xiaolan; Et Al
  参考文献:Crystengcomm 日期:2014 卷标:16(13) 页码:2779-2787]
  
  73183-34-3 + 18179-39-0 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 16 H,130 °C2.1 Reagents: Cesium Fluoride Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 24 H,110 °C3.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 24 H,50 °C; 50 °C -> Rt3.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
  标题:Novel Ni-Irmof-74 Postsynthetically Functionalized For H2 Storage Applications
  作者:Montes-Andres,Helena; Et Al
  参考文献:Journal Of Physical Chemistry C 日期:2018 卷标:122(49) 页码:28123-28132]
  
  854028-46-9 + 73183-34-3 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Acetate Catalysts: Dichlorobis(Triphenylphosphine)Palladium2.1 Reagents: Cesium Fluoride Catalysts: Palladium Chloride Solvents: 1,4-Dioxane,Water; 90 °C3.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate3.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Molecular Insight Into Fluorocarbon Adsorption In Pore Expanded Metal-Organic Framework Analogs
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2020 卷标:142(6) 页码:3002-3012]
  
  854028-46-9 + 73183-34-3 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Acetate Catalysts: Dichlorobis(Triphenylphosphine)Palladium Solvents: 1,4-Dioxane; Rt; Rt -> 130 °C; 16 H,130 °C; 130 °C -> Rt2.1 Reagents: Cesium Fluoride Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 14 H,90 °C3.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate; 24 H,Rt -> 50 °C3.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Pore-Engineered Metal-Organic Frameworks With Excellent Adsorption Of Water And Fluorocarbon Refrigerant For Cooling Applications
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2017 卷标:139(31) 页码:10601-10604]
  
  65-49-6 + 814-68-6 = 861533-46-2 + 109507-30-4 + 69-72-7
  反应条件:1.1 Solvents: Benzene; 0 °C2.1 Catalysts: Azobisisobutyronitrile Solvents: Dimethylformamide; 6 H,Reflux3.1 Rt -> 500 °C
  标题:Thermal Stability And Degradation Of (4-(Acrylamido)-2-Hydroxybenzoic Acid) Homopolymer And Copolymer Of 4-(Acrylamido)-2-Hydroxybenzoic Acid With Methyl Methacrylate
  作者:Diab,M. A.; Et Al
  参考文献:Synthesis And Reactivity In Inorganic 日期:2015 卷标:45(9) 页码:1439-1447]
  
  861600-12-6 = 861533-46-2
  反应条件:1.1 Reagents: Hydrogen Bromide Solvents: Acetic Acid; 8 H,127 °C
  标题:Three 3D Lanthanide-Organic Frameworks With Sra Topology: Syntheses,Structures,Luminescence And Magnetic Properties
  作者:Liu,Xiaolan; Et Al
  参考文献:Crystengcomm 日期:2014 卷标:16(13) 页码:2779-2787]
  
  202831-18-3 = 861533-46-2
  反应条件:1.1 Reagents: Pyridinium Chloride; 3 H,210 - 220 °C; 220 °C -> 100 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; 100 °C -> Rt
  标题:Synthesis And Characterization Of 3,3'-Dihydroxy-1,1'-Biphenyl-4,4'-Dicarboxylic Acid
  作者:Zhou,Jun; Et Al
  参考文献:Nanjing Gongye Daxue Xuebao 日期:2007 卷标:29(1) 页码:16-18]
  
  202831-18-3 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Hydroxide,Hydrochloric Acid Solvents: Methanol; 65 °C2.1 Reagents: Hydrogen Bromide Solvents: Acetic Acid; 8 H,127 °C
  标题:Three 3D Lanthanide-Organic Frameworks With Sra Topology: Syntheses,Structures,Luminescence And Magnetic Properties
  作者:Liu,Xiaolan; Et Al
  参考文献:Crystengcomm 日期:2014 卷标:16(13) 页码:2779-2787]
  
  1073355-16-4 + 854028-46-9 = 861533-46-2
  反应条件:1.1 Reagents: Cesium Fluoride Catalysts: Palladium Chloride Solvents: 1,4-Dioxane,Water; 90 °C2.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate2.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Molecular Insight Into Fluorocarbon Adsorption In Pore Expanded Metal-Organic Framework Analogs
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2020 卷标:142(6) 页码:3002-3012]
  
  1073355-16-4 + 854028-46-9 = 861533-46-2
  反应条件:1.1 Reagents: Cesium Fluoride Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 14 H,90 °C2.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate; 24 H,Rt -> 50 °C2.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Pore-Engineered Metal-Organic Frameworks With Excellent Adsorption Of Water And Fluorocarbon Refrigerant For Cooling Applications
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2017 卷标:139(31) 页码:10601-10604]
  
  1073371-99-9 + 18179-39-0 = 861533-46-2
  反应条件:1.1 Reagents: Cesium Fluoride Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 24 H,110 °C2.1 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 24 H,50 °C; 50 °C -> Rt2.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
  标题:Novel Ni-Irmof-74 Postsynthetically Functionalized For H2 Storage Applications
  作者:Montes-Andres,Helena; Et Al
  参考文献:Journal Of Physical Chemistry C 日期:2018 卷标:122(49) 页码:28123-28132]
  
  148490-97-5 = 861533-46-2
  反应条件:1.1 Reagents: Copper; 3 H,210 - 220 °C2.1 Reagents: Pyridinium Chloride; 3 H,210 - 220 °C; 220 °C -> 100 °C2.2 Reagents: Hydrochloric Acid Solvents: Water; 100 °C -> Rt
  标题:Synthesis And Characterization Of 3,3'-Dihydroxy-1,1'-Biphenyl-4,4'-Dicarboxylic Acid
  作者:Zhou,Jun; Et Al
  参考文献:Nanjing Gongye Daxue Xuebao 日期:2007 卷标:29(1) 页码:16-18]
  
  18179-39-0 = 861533-46-2
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Acetonitrile2.1 Reagents: Cesium Fluoride Catalysts: Palladium Chloride Solvents: 1,4-Dioxane,Water; 90 °C3.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Tetrahydrofuran,Ethyl Acetate3.2 Reagents: Sodium Hydroxide Solvents: Tetrahydrofuran,Water; 50 °C
  标题:Molecular Insight Into Fluorocarbon Adsorption In Pore Expanded Metal-Organic Framework Analogs
  作者:Zheng,Jian; Et Al
  参考文献:Journal Of The American Chemical Society 日期:2020 卷标:142(6) 页码:3002-3012]
  
  65-49-6 = 861533-46-2
  反应条件:1.1 Reagents: Sodium Nitrite,Sulfuric Acid Solvents: Water; Rt -> 0 °C; 10 Min,0 - 5 °C1.2 Reagents: Cuprous Iodide; 1 H,< 5 °C2.1 Reagents: Potassium Carbonate Solvents: Acetone; 8 H,Reflux3.1 Reagents: Copper; 3 H,210 - 220 °C4.1 Reagents: Pyridinium Chloride; 3 H,210 - 220 °C; 220 °C -> 100 °C4.2 Reagents: Hydrochloric Acid Solvents: Water; 100 °C -> Rt
  标题:Synthesis And Characterization Of 3,3'-Dihydroxy-1,1'-Biphenyl-4,4'-Dicarboxylic Acid
  作者:Zhou,Jun; Et Al
  参考文献:Nanjing Gongye Daxue Xuebao 日期:2007 卷标:29(1) 页码:16-18]
  
  65-49-6 = 861533-46-2
  反应条件:1.1 Reagents: Sodium Nitrite,Sulfuric Acid,Cuprous Iodide; 0 - 5 °C2.1 80 °C3.1 Catalysts: Copper; 210 - 220 °C4.1 Reagents: Potassium Hydroxide,Hydrochloric Acid Solvents: Methanol; 65 °C5.1 Reagents: Hydrogen Bromide Solvents: Acetic Acid; 8 H,127 °C
  标题:Three 3D Lanthanide-Organic Frameworks With Sra Topology: Syntheses,Structures,Luminescence And Magnetic Properties
  作者:Liu,Xiaolan; Et Al
  参考文献:Crystengcomm 日期:2014 卷标:16(13) 页码:2779-2787]
  
  24599-26-6 = 861533-46-2 + 109507-30-4 + 69-72-7
  反应条件:1.1 Rt -> 500 °C
  标题:Thermal Stability And Degradation Of (4-(Acrylamido)-2-Hydroxybenzoic Acid) Homopolymer And Copolymer Of 4-(Acrylamido)-2-Hydroxybenzoic Acid With Methyl Methacrylate
  作者:Diab,M. A.; Et Al
  参考文献:Synthesis And Reactivity In Inorganic 日期:2015 卷标:45(9) 页码:1439-1447

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