CAS: 849-55-8; Nylidrin Hydrochloride

上下游产品

-2-bromo-1-propanone1-4-(benzyloxy)phenyl-2-bromo-1-propanone (RS)-1-methyl-3-phenylpropylamine 26H29NO2*ClHC26H29NO2*ClH

📜2-(4-Phenylbutan-2-Ylamino)-1-(4-Phenylmethoxyphenyl)Propan-1-One;Hydrochloride置于3% Pd/c,氢气体系中,用 甲醇 作为反应溶剂,以95%的收率获得产物布芬宁盐酸盐
参考文献:一种盐酸布酚宁的制备方法
标题:一种盐酸布酚宁的制备方法
摘要:本发明涉及一种盐酸布酚宁的制备方法,包括制备中间体iv和盐酸布酚宁.本发明方法操作简便,适合于工业化生产,产物纯度较高,质量达到人用药物制剂的使用标准.

专利信息

专利号:US-8354116-B2
优先权日:2007-06-18
标题 :Bifunctional synthetic molecules
发明人：CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
权利人:BIOCHEMICS INC; CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
摘要:The synthesis and use of bifunctional molecules to improve the topical and transdermal delivery efficiency of various types of therapeutic agents or agents designed to promote the transdermal delivery of those therapeutic agents either into the skin tissue or into the systemic circulation. Three major classes of molecules are covalently joined as bifunctional substances; chemical vasodilators, passive dermal penetration enhancers and therapeutic or diagnostic drugs. Chemical vasodilators may be delivered into the skin to increasing the blood flow in a tissue that has compromised circulation or they may be used as part of a delivery vehicle to promote the delivery of the drug. Passive dermal penetration enhancers are those chemicals that promote the passive penetration of drugs and other chemicals through the stratum corneum and epidermis of the skin tissue. Drugs and diagnostic agents are the third group of chemicals that are candidates for the linkage of molecules.