CAS: 772-54-3; N-Benzyl-N-Ethylethanamine

该化合物是一种有机化合物,其特征是其有矿功能组,其结构包括一个以二乙基组和甲基胺酸性替代的苯环,该化合物一般是无色的黄色液体,可粉黄,有独特的一种矿泉水味,在有机溶剂中溶解,但因其疏水性而在水中溶解性有限.N,N-二乙基苯基苯胺主要用于各种化学中间体的合成,可以作为有机反应的试剂.它可能由于矿体组的存在而具有基本特性,允许其参与酸基反应.安全考虑包括对皮肤和眼睛的潜在刺激作用,在通风良好的环境中应以适当的防范措施处理它.与许多氨一样,它也可能发生氧化,或与强酸反应,形成盐.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号1696-17-9 N,N-耳乙基苯甲酰胺 | CAS号100-52-7 苯甲醛 | CAS号109-89-7 二乙胺 | CAS号100-39-0 溴化苄 | CAS号100-51-6 苯甲醇 | CAS号13686-66-3 N,N-二乙基-1,1-二甲基甲硅烷基胺 | CAS号1125-88-8 苯甲醛二甲缩醛 | CAS号75-03-6 碘乙烷 | CAS号100-46-9 苄胺 | CAS号14999-74-7 Diethylammonium... | CAS号20689-96-7 N-NITROSO-N-ETH... | CAS号100-52-7 苯甲醛 | CAS号65-85-0 苯甲酸 | CAS号100-39-0 溴化苄 | CAS号121-44-8 三乙胺 | CAS号108-88-3 甲苯 | CAS号833-50-1 2-苯基苯并恶唑 | CAS号716-79-0 2-苯基苯并咪唑 | CAS号5197-95-5 苄基三乙基溴化铵 | CAS号1696-17-9 N,N-耳乙基苯甲酰胺

合成工艺路线路线简述

  • 合成目标产物 N-Benzyldiethylamine 主要起始原料 Diethylamine And Benzyl Alcohol
  • (文献来源)合成步骤主要原料 Diethylamine 和 Benzyl Alcohol
N-苄基-N-乙基乙酰胺置于dimethyl Sulfide Borane体系中,用 甲苯 作为反应溶剂,化学反应 4.0H,以78%的收率获得产物n,N-二乙基苄胺
参考文献:温度对仲酰胺和叔酰胺的硼烷二甲基硫醚还原反应化学计量的影响
标题:温度对仲酰胺和叔酰胺的硼烷二甲基硫醚还原反应化学计量的影响
摘要:摘要 描述了使用理论量的硼烷-二甲硫醚将仲酰胺和叔酰胺还原为胺的简单程序.
DOI:10.1080/00397919108021056

海关参考信息

专利信息


专利号:US-2025026643-A1
优先权日:2021-12-03
标题 :Production of anhydrous quaternary ammonium hydroxides
发明人:ZHOU HUI; ZHANG KE
权利人:HUNTSMAN PETROCHEMICAL LLC
摘要:A method for the synthesis of anhydrous quaternary ammonium hydroxides having the formula (NR 1 R 2 R 3 R 4 ) OH, wherein R 1 , R 2 , R 3 and R 4 are the same as or different from one another and are each individually selected from H, C 1 -C 10 alkyls including linear or cyclo alkyls, and C 6 -C 12 aryls by reacting an alkylene oxide with a tertiary amine having the formula R 1 R 2 R 3 N wherein R 1 , R 2 , and R 3 are the same or different and are each individually selected from C 1 -C 10 alkyls including linear and cyclo alkyls, C 1 -C 10 hydroxyalkyls, C 6 -C 12 aryls, and formulations having anhydrous quaternary ammonium hydroxides.

专利号:US-2024287084-A1
优先权日:2021-10-28
标 题 :Synthesis of [1,2,3]triazolo[4,5-d]pyrimidines
发明人:ADAM JEAN-MICHEL; GRETHER UWE; MOESSNER CHRISTIAN; TOSATTI PAOLO
权利人:HOFFMANN LA ROCHE
摘要:The present invention relates to a process for the preparation of [1,2,3]triazolo[4,5-d]pyrimidine derivatives useful as pharmaceutically active compounds, in particular 1-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-ol.

专利号:WO-2011148392-A1
优先权日:2010-05-28
标题 :Process for the preparation of (2s,4s,5s,7s)-n-(2-carbamyl-2- methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3- methoxypropoxy)phenyl]-octanamide hemifumarate and its intermediates thereof
发明人:SATYANARAYANA REDDY MANNE; THIRUMALAI RAJAN SRINIVASAN; ESWARAIAH SAJJA; VENKAT REDDY GHOJALA; RAMA SUBBA REDDY KARAMALA; SAHADEVA REDDY MARAMREDDY
权利人:MSN LAB LTD; SATYANARAYANA REDDY MANNE; THIRUMALAI RAJAN SRINIVASAN; ESWARAIAH SAJJA; VENKAT REDDY GHOJALA; RAMA SUBBA REDDY KARAMALA; SAHADEVA REDDY MARAMREDDY
摘要:The present invention relates to a process for the preparation of (2S,4S,5S,7S)-N-(2- Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxy propoxy )phenyl]-octanamide compound of formula- 1 and its pharmaceutically acceptable salts thereof. Further, relates to the processes for the preparation of (R)-4-(2-(halomethyl)-3- methylbutyl)-l-methoxy-2-(3-methoxypropoxy) benzene and (R)-2-(4-methoxy-3-(3-methoxy propoxy) benzyl)-3-methyIbutan-l-ol useful intermediates in the synthesis of compound of formula- 1.

专利号:WO-8503665-A1
优先权日:1984-02-15
标题:Synthesis of polyurethane products
发明人:HOSTETTLER FRITZ
权利人:PIRRI JAQUELYN P; HOSTETTLER FRITZ
摘要:Wide range of polyurethane products, e.g., cellular, dense elastomer, and integral skin microcellular products, obtained by the reaction of (a) a polyisocyanate compound, (b) a polyol, (c) optionally a chain extender and/or blowing agent with/without other known additives, (d) in the presence of a nonhydroxyl flow modifier characterized by carbon and hydrogen atoms, at least one and, generally, a plurality of oxyalkylene groups, and at least one urethane, $(1,5)omicronp. Several of the polyurethane products exhibit unique properties, e.g., foamed articles with capability to conduct static electricity, soft elastomers characterized by improved coefficient of friction, etc. Several classes of the flow modifiers are novel per se. The polyurethane products can be synthesized via the one shot or prepolymer process. Multipackage systems, in particular, two and three component systems are useful in molding operations, e.g., manufacture of shoe soles.

专利号:US-8168556-B2
优先权日:2007-10-25
标 题 :Racemoselective synthesis of ansa-metallocene compounds, ansa-metallocene compounds, catalysts comprising them, process for producing an olefin polymer by use of the catalysts, and olefin homo- and copolymers
发明人:SCHULTE JOERG; SELL THORSTEN; THORN MATTHEW GRANT; WINTER ANDREAS; DIMESKA ANITA
权利人:SCHULTE JOERG; SELL THORSTEN; THORN MATTHEW GRANT; WINTER ANDREAS; DIMESKA ANITA; LUMMUS NOVOLEN TECHNOLOGY GMBH
摘要:A metallocene compound with the 4- and 7-positions on the indenyl moiety possessing large aromatic substituents is prepared in accordance with a method which produces substantially 100 percent racemic isomer. Advantageously, polymerization catalysts including the metallocene of the invention provide superior olefin polymerization results.

专利号:US-2016122450-A1
优先权日:2013-05-08
标题:Synthesis of a substituted furan
发明人:ZHANG YUGEN; TEONG SIEW PING; YI GUANGSHUN
权利人:AGENCY SCIENCE TECH & RES
摘要:The present invention provides a polymer comprising an aliphatic backbone having a plurality of aromatic rings bonded thereon, said plurality of aromatic rings comprising a first aromatic ring type that has an alkyl halide group substitution on the aromatic ring and a second aromatic ring type that has an optionally substituted ammonium halide group substitution on the aromatic ring. The present invention also provides a method for making an optionally substituted furan, the method comprising the step of subjecting a sugar to a dehydration reaction in the presence of a catalyst comprising said polymer.
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主要参考文献

参考标题:Synthesis Of Novel Intermediate(S) For Preparing Rivastigmine
摘要:The Present Invention Relates To Novel Intermediate(S), Which Are Useful For The Preparation Of Rivastigmine Compound Of Formula (I) And Its Pharmaceutically Acceptable Salts. The Present Invention Further Relates To The Processes For The Preparation Of Such Novel Intermediate(S) And Preparation Of Rivastigmine Using Such Novel Intermediate(S).

合成参考文献


摘要:Margaretha, P., Science of Synthesis Knowledge Updates, (2010) 4, 411.
摘要:Claver, C.; Peñafiel, I.; Urrutigoïty, M.; Kalck, P., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 318.
摘要:Li, H.; Wang, Y.; Liu, Q., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 555.
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