CAS: 55612-21-0; 2'-Deoxy-2'-Fluoro-5-Iodouridine

相似化合物

69123-98-4 784-71-4 69123-94-0

上下游产品

2'-deoxy-2'-fluorouridine 3',5'-O-acetyl-2'-deoxy-2'-fluorouridine ((2R,3R,4R,5R)-3-acetoxy-4-fluoro-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate (E)-5-(2-iodovinyl)-2'-ribofluoro-2'-deoxyuridine

专利信息

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-9481705-B2
优先权日:2008-08-19
标题:Modular radiochemistry synthesis system
发明人：SATYAMURTHY NAGICHETTIAR; BARRIO JORGE R; AMARASEKERA BERNARD; VAN DAM R MICHAEL; OLMA SEBASTIAN; WILLIAMS DIRK; EDDINGS MARK; SHEN CLIFTON KWANG-FU
权利人:UNIV CALIFORNIA
摘要:A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

专利号:US-2020239500-A1
优先权日:2018-04-04
标 题 :Compositions and Methods for Synthesis of Phosphorylated Molecules

专利号:US-2009298708-A1
优先权日:2006-08-23
标题 :2'-deoxy-2'-fluoro-beta-d-arabinonucleoside 5'-triphosphates and their use in enzymatic nucleic acid synthesis
发明人：MASAD DAMHA J; GENG PENG CHANG
权利人:MASAD DAMHA J; GENG PENG CHANG
摘要:The invention relates to arabinose modified nucleoside 5′ triphosphates and to the biosynthesis and amplification of oligonucleotides containing and/or from templates containing arabinose modified nucleosides. The invention further relates to methods of generating modified oligonucleotide libraries for use in selection strategies, such as SELEX. The arabinose modified oligonucleotides of the invention are useful for modulating target nucleic acid expression, such as RNA.

专利号:WO-2019195494-A1
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules

专利号:US-4879377-A
优先权日:1983-11-18
标题:Nucleoside process
发明人：BRUNDIDGE STEVEN P; HOWELL HENRY G; SAPINO JR CHESTER; HONG-TANN CHOU
权利人:BRISTOL MYERS CO
摘要:Process for producing 1-halo-2-deoxy-2-fluoroarabinofuranoside derivatives bearing protective ester groups from 1,3,5-tri-O-acylribofuranose; the 1-halo compounds are intermediates in the synthesis of therapeutically active nucleosidic compounds.