CAS: 52314-67-7; 3-(2,2-Dichloroethenyl)-2,2-Dimethylcyclopropane-1-Carbonyl Chloride

该化合物是一种化学化合物,其独特结构包括环丙烷环和碳基氯功能组,该化合物具有二氯乙烯基替代成分,有助于其再活动并有可能应用于有机合成.氯碳基化合物组的存在表明,它可以参与核生殖性乙基替代反应,使其在合成各种有机化合物时有用.此外,二氯乙烯基组可产生特定的电子特性,影响化合物的再活动性和稳定性.与许多氯化化合物一样,必须谨慎处理该物质,同时顾及潜在的毒性和环境关切.其物理特性,如沸点,熔点和溶性,通常将通过实验方法来确定,并且应当参考安全数据表,以便正确处理和处置准则.

英文名称3-(2,2-Dichloroethenyl)-2,2-Dimethylcyclopropane-1-Carbonyl Chloride
中文名称氯氰菊酰氯
IUPAC名称3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carbonyl chloride
其它别名2,2-Dimethyl-3-(2,2-dichloroethenyl)cyclopropanecarbonylchloride; 2,2-Dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarbonyl chloride; 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarbonyl chloride; 3-(2,2-Dichlorovinyl)-2,2-dimethyl-1-cyclopropanecarbonyl chloride; 3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarbonyl chloride
CAS编号52314-67-7
MFCD编号:MFCD00071724
EINECS号:257-840-8
分子式:C8H9Cl3O
分子量:227.52
产品CID: 2514778
产品分类化学农药原药 → 杀虫剂中间体

相似结构搜索
产品信息参考;;;;
InChIKey: CHLAOFANYRDCPD-UHFFFAOYNA-N
InChI=1/C8H9Cl3O/c1-8(2)4(3-5(9)10)6(8)7(11)12/h3-4,6H,1-2H3…
计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数2.0

物理性质

沸点242.4±30.0 °C at 760 mmHg
闪点98.9±25.1 °C
密度1.4±0.1 g/cm3
PSA:17.07
LogP:3.27
折射率1.581
蒸汽压0.0±0.5 mmHg at 25°C
溶解性Chloroform (Sparingly), Methanol (Slightly)
外观形态无色至淡黄色油状物
储存条件2-8°C
产品应用该化合物用于除虫菊酯的重要中间体,以制备农药,如丙烯菊酯,氯苯菊酯,乙基苯丙菊酯和戊基丙烯基乙酰菊酯等.

MSDS等安全信息

GHS象形图
GHS符号GHS06 & GHS09;
注释: Skull and crossbones & Environment
危险类别急性毒性类别4(吸入)
急性毒性类别3(经口)
特定目标器官毒性 - 单次接触类别3
特定目标器官毒性-重复接触类别2
皮肤腐蚀/刺激类别2
皮肤致敏类别1
水生急性毒性类别1
水生慢性毒性类别1
急性毒性类别4(经口)
皮肤腐蚀类别1C
警示词Danger(危险)
危险描述H332 |吸入有害.
H301 |吞咽会中毒.
H335 |可能引起呼吸道刺激.
H373 |长期或反复接触可能损害器官.
H315 |造成皮肤刺激.
H317 |可能引起皮肤过敏反应.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响.
H302 |吞咽有害.
H314 |造成严重皮肤灼伤和眼损伤.
防范说明P264-P270-P301+P310-P321-P330-P405-P501-P260-P314-P501-P273-P391-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P312-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
危险品标志Xn

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

合成目标产物 3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarbonyl Chloride 主要起始原料 Permethric Acid
(文献来源)合成步骤主要原料 Permethric Acid

二氯菊酸置于氯化亚砜体系中,化学反应生成氯氰菊酰氯
参考文献:Synthesis Of New Chiral And Nonchiral Pyrido [3,2-E],[1,3,4] Oxadiazine Derivatives
标题:Synthesis Of New Chiral And Nonchiral Pyrido [3,2-E],[1,3,4] Oxadiazine Derivatives
摘要:一系列手性的6,7-二氯-3-[3-(2,2-二卤乙烯基)-2,2-二甲基环丙基]-1H-吡啶[3,2-E],[1,3,4]噁二嗪(a-F),以及一系列非手性的3-取代基,6,7-二氯-1H-吡啶[3,2-E][1,3,4]噁二嗪(a-G)已经被合成.这些合成化合物通过红外光谱(ir),核磁共振氢谱(1H Nr),高效液相色谱(HPLC)和质谱数据进行了表征.
DOI:10.1155/2010/791796

海关参考信息

2901210000-乙烯
2901220000-丙烯
2903210000-氯乙烯
2912110000-甲醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-10647655-B2
优先权日:2016-09-02
标题:Method for the synthesis of permethrin
发明人：PULLAGURLA MANIK REDDY; NANDA KUMAR MECHERIL VALSAN; VELIGETLA MADHUSUDHANA RAO; RANGISETTY JAGADEESH BABU
权利人:BIOPHORE INDIA PHARMACEUTICALS PVT LTD
摘要:An improved method for the synthesis of substantially pure Permethrin having purity greater than 99.5% by Gas Chromatography provided. The embodiments also relates to a purification process of Permethrin by recrystallization from methanol-water mixture.

专利号:US-2019194118-A1
优先权日:2016-09-02
标题:Improved method for the synthesis of permethrin

专利号:US-4338468-A
优先权日:1978-06-27
标题:Î±-Prop-1-ynyl-3-phenoxybenzyl alcohols
发明人：FAROOQ SALEEM; ACKERMANN PETER; DRABEK JOZEF; GSELL LAURENZ; KRISTIANSEN ODD; WEHRLI RUDOLF
权利人:CIBA GEIGY CORP
摘要:Î±-Prop-1-ynyl-3-phenoxybenzyl alcohols of the formula ##STR1## wherein Y represents hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 3 alkoxy, cyano or dimethylamino, a process for their manufacture and their use as intermediates for the synthesis of compounds which are suitable for pest control, and which are especially suitable because of their low fish toxicity, for the control of rice pests e.g. Chilo suppressalis in rice paddies where fish are kept.

专利号:US-5925676-A
优先权日:1996-09-13
标题 :Ester compounds pesticidal compositions containing the same and itermediates for synthesis thereof
发明人：IWASAKI TOMONORI; TSUSHIMA KAZUNORI; SUGANO MASAYO
权利人:SUMITOMO CHEMICAL CO
摘要:An ester compound represented by the formula ##STR1## wherein R 1 and R 2 may be the same or different and each represent a C 1 -C 6 alkyl group, or other specified groups, which may be optionally substituted with one or more halogen atoms; and R 3 represents a pyrethroid acid residue (a group resulting from elimination of the carboxyl group from pyrethroid acid), and a pesticidal composition containing the ester compound as an active ingredient.

专利号:EP-3506748-A1
优先权日:2016-09-02
标题:Improved method for the synthesis of permethrin