CAS: 52225-20-4; (R)-Rel-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-Trimethyltridecyl)Chroman-6-Yl Acetate

该化合物是一种合成形式的维生素E,通常用于抗氧化性特性和稳定性.乙酸酯会增加氧化性抗药性,使其适合需要较长保存期的应用,如药品,化妆品和食品强化.它的亲脂性能能能确保与脂质配方的兼容性.作为一种种族混合物,它提供与自然异构体相比具有成本效益的功能. 众所周知,它能保护细胞免受氧化性压力的影响,常常被融入用于保护皮肤或口服补充的热能产品中. 该化合物在热和光下的稳定性进一步支持其在工业和营养应用中的使用.

结构式图片

上下游产品

3,5,6-trimethyl-2-phytylhydroquinone acetic anhydride vitamin E α-t°Cotrienolvitamin E Duroquinone N-(phenylmethyl)acetamide

合成工艺路线路线简述

    📜天然维生素e 反应生成 D-Alpha-生育酚醋酸酯
    参考文献:Process For The Preparation Of Tocol Acylates And Tocopherol Acylates
    标题:Process For The Preparation Of Tocol Acylates And Tocopherol Acylates
    摘要:本发明涉及一种制备生育酚酰化物或生育醇酰化物的方法,其步骤如下:A) 将生育酚或生育醇与酰化剂混合形成反应混合物;b) 用微波能量辐射反应混合物以形成生育酚酰化物或生育醇酰化物;c) 从反应混合物中分离出生育酚酰化物或生育醇酰化物.

    海关参考信息

    专利信息


    专利号:US-12383499-B2
    优先权日:2018-01-01
    标题:Scale up synthesis of silicasome nanocarriers
    发明人:NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
    权利人:UNIV CALIFORNIA
    摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

    专利号:US-4182719-A
    优先权日:1977-05-17
    标题 :Synthesis of optically active vitamin E
    发明人:COHEN NOAL; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.

    专利号:US-4208332-A
    优先权日:1977-05-17
    标 题:Synthesis of optically active vitamin E
    发明人:COHEN NOAL; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.

    专利号:US-4208331-A
    优先权日:1977-05-17
    标 题:Synthesis of optically active vitamin E
    发明人:COHEN NOAL; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.

    专利号:US-4151177-A
    优先权日:1977-05-17
    标题:Synthesis of optically active vitamin E
    发明人:COHEN NOAL; SAUCY GABRIEL
    权利人:HOFFMANN LA ROCHE
    摘要:Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.

    专利号:US-2023091651-A1
    优先权日:2021-09-20
    标 题:Dietary supplement and method for synthesis of same
    发明人:WYNN JASON R
    权利人:StrongCell LLC
    摘要:A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided that includes at least partially microencapsulated nicotinamide having nicotinamide blended with water. A supplement component, such as collagen, coenzyme Q10, vitamins, and minerals, is provided. A mixed component, which is a liquid, is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is subjected to a fill production process.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:International Journal of Toxicology 21(Suppl. 3):51-116, 2002
    摘要:Final Report 3/2014 Available from CIR
    参考文献:10.1385/bter:110:2:133
    摘要:Nielsen FH. A mild magnesium deprivation affects calcium excretion but not bone strength and shape, including changes induced by nickel deprivation, in the rat. Biol Trace Elem Res. 2006 May;110(2):133–50. doi: 10.1385/bter:110:2:133.
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