CAS: 4536-30-5; 2-(Dodecyloxy)Ethanol

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📜十二烷醇置于sodium Hydride,对甲苯磺酸体系中,用 甲醇 作为反应溶剂,化学反应生成 乙二醇单十二烷基醚
参考文献:Structure-Activity Relationship Of Lipopeptide From Outer Membrane Of Escherichia Coli And Synthesis Of Highly Immunopotenting Lipopeptide Derivatives With An Achiral Lipo-Part.
标题:Structure-Activity Relationship Of Lipopeptide From Outer Membrane Of Escherichia Coli And Synthesis Of Highly Immunopotenting Lipopeptide Derivatives With An Achiral Lipo-Part.
摘要:为了突出脂肽衍生物的结构-活性关系,新近合成了具有非手性脂部分的生物活性高的脂肽衍生物.
DOI:10.1248/cpb.41.627

专利信息

专利号:US-2012190064-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
发明人：KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

专利号:US-5919969-A
优先权日:1996-06-05
标 题 :Synthesis of yellow couplers
发明人：CRAWLEY MICHAEL W
权利人:EASTMAN KODAK CO
摘要:The invention provides a method of synthesis of a image-dye forming coupler of formula (I) wherein X is a substituent linked to the coupler by an atom of oxygen, sulfur or nitrogen R1 is an alkyl or aryl group, R2 is a hydrogen atom or an alkyl group; R3 to R7 are the same or different and selected from a hydrogen atom and substituent groups; which method comprises the reaction of a compound of formula (II) wherein R and R1 are the same or different and are as defined above for R1 and X is as defined above with a compound of formula (III) wherein R2 to R7 are as defined above, in the presence of an inert organic solvent.

专利号:US-10793495-B2
优先权日:2015-08-14
标 题:Synthesis of polyaryl substituted aryl compounds
发明人：BOULOS RAMIZ; FEUTRILL JOHN
权利人:BOULOS & COOPER PHARMACEUTICALS PTY LTD
摘要:A method for the synthesis of a aryl compound of Formula (1).n nU T-W—R 1 ) n    (1)

专利号:US-8546532-B2
优先权日:2008-04-17
标题:Synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders
发明人：BONNIN DUSTAN; ZANELLI ERIC; MATHERS THOMAS
权利人:BONNIN DUSTAN; ZANELLI ERIC; MATHERS THOMAS; DECLION PHARMACEUTICALS INC
摘要:The instant invention comprises a process for the solid phase synthesis of directed epitope peptide mixtures useful in the treatment and diagnosis of protein conformational disorders, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use. The invention also pertains to the process of generating antibodies using the directed epitope peptide mixtures as the antigens, and antibodies generated by such process, useful in the treatment and diagnostics of the said protein conformational disorder.

专利号:US-6664396-B1
优先权日:2002-06-27
标 题 :One step synthesis for quinacridone compounds
发明人：COSIMBESCU LELIA
权利人:EASTMAN KODAK CO
摘要:Disclosed is a process for forming a N,N'-diarylquinacridone compound comprising the step of reacting a N,N'-unsubstituted quinacridone compound with a haloaryl compound in the presence of a metal or metal compound to arylate the N and N' positions and form the corresponding N,N'-diarylquinacridone compound. The process is versatile and provides high yields and purity for the synthesis of N,N'-diarylquinacridone compounds.

专利号:US-9149659-B2
优先权日:2012-11-14
标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles
发明人：PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER
权利人:COTY GERMANY GMBH
摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.