CAS: 3546-50-7; Pyrimidine-2,4,5-Triamine

相似化合物

13754-19-3 118-70-7 156-81-0

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CAS号18620-73-0 2,4-二氨基-5-硝基嘧啶 | CAS号7647-01-0 盐酸 | CAS号452-06-2 2-氨基嘌呤 | CAS号100516-92-5 6,7-Pteridinedi... | CAS号700-81-2 2-Pteridinamine... | CAS号79318-62-0 4-[[(2,4-diamin...

专利信息

专利号:US-6096900-A
优先权日:1999-05-07
标 题 :Solventless preparation of phthalimides
发明人：NICK ROBERT JOSEPH; NELSON MARK ERIK; CARINGI JOSEPH JOHN; WILLIAMS DREW ELLIOT
权利人:GEN ELECTRIC
摘要:A method for the solventless synthesis of a phthalimide or phthalimide mixture is provided comprising contacting at least one amine reactant and at least one anhydride reactant in a solventless environment at a first temperature sufficient to allow the reactants to at least partially condense; and increasing the temperature to a second temperature sufficient to melt the reaction mixture, thereby allowing the reaction to go essentially to completion and form the reaction product.

专利号:US-4167633-A
优先权日:1977-07-20
标题 :Preparation of 2,4,5,6-tetraaminopyrimidine from 2,4,6-triaminopyrimidine
发明人：MORROW THOMAS J
权利人:US HEALTH EDUCATION & WELFARE
摘要:An improved process for the production of ##STR1## FROM ##STR2## WHICH PRODUCES BUT DOES NOT ISOLATE AN INTERMEDIATE ##STR3## WHICH COMPOUND IS RETAINED IN SITU AND MINIMIZES THE COMPLEX POLYMER FORM OF A THREE-DIMENSIONAL NETWORK OF AZO LINKAGES FORMED BY THE NITROSO AND AMINO GROUPS. These groups, as they appear in the nitroso intermediate, have carcinogenic possibilities. It has been found that the nitroso compound will precipitate as a stirrable slurry if the temperature parameter is kept low at about 0°-20° C. A preferred route for the production of the nitroso compound from the triamino starting material utilizes as reactants 1.0-1.05 moles of sodium nitrite and 1.5 moles of HOAc in water (HCl may be substituted for HOAc). In the second state of this sequential reaction, the reduction of nitroso is carried out by a reducing agent and one preferred agent is sodium dithionite. Catalytic agents such as Raney nickel and hydrazine or nickel salts, e.g., nickel chloride, and sodium borohydride may also be used. The present process is an improvement in part of the technique of Piper and Montgomery, J. Het. Chem., 11:279 (1974), which process is designed specially to produce the antifolate methotrexate as an end product and is an improvement of the method of application Ser. No. 742,450 of Ellard filed Nov. 17, 1976, entitled 'Improved Synthesis of Methotrexate', U.S. Pat. No. 4,080,825.

专利号:US-6262223-B1
优先权日:1999-02-03
标题:Triamine-modified polymides having improved processability and low melt flow viscocity
发明人：MEADOR MICHAEL A; NGUYEN BAOCHAU N; EBY RONALD K
权利人:US ADMINISTRATOR OF NAT AERONA
摘要:Addition-cured polyimides that contain the reaction product of an aromatic triamine or trianhydride analogue thereof, a reactive end group such as 5-norbornene-2, 3-dicarboxylic acid, ester derivatives of 5-norbornene-2,3-dicarboxylic acid, anhydride derivatives of 5-norbornene-2,3-dicarboxylic acid, or 4-phenylethynylphthalic anhydride, an aromatic diamine, and a dialkyl ester of an aromatic tetracarboxylic acid. The resultant starlike polyimides exhibit lower melt flow viscosity than its linear counterparts, providing for improved processability of the polyimide. Also disclosed are methods for the synthesis of these polyimides as well as composite structures formed using these polyimides.

专利号:US-9943809-B2
优先权日:2014-02-27
标题 :Solvent resistant thin film composite membrane and its preparation
发明人：DOM ELKE; HERMANS SANNE; KOECKELBERGHS GUY; VANKELECOM IVO
权利人:KATHOLIEKE UNIV LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT; UNIV LEUVEN KATH
摘要:The present invention relates to improved methods for synthesis of thin film composite membranes by interfacial polymerization. More in particular, the method of the present invention comprises the impregnation of an ultrafiltration porous support membrane with an aqueous solution containing a polyfunctional nucleophilic monomer, and contacting the impregnated support membrane with a second largely water-immiscible solvent containing a polyfunctional epoxide monomer.

专利号:WO-2010130900-A3
优先权日:2009-05-15
标 题 :Triaminopyrimidine derivatives as cdc25 phosphatase inhibitors
发明人：LIBERATORE ANNE-MARIE; PREVOST GREGOIRE; AUVIN SERGE; BREHU LAETITIA
权利人:IPSEN PHARMA SAS; LIBERATORE ANNE-MARIE; PREVOST GREGOIRE; AUVIN SERGE; BREHU LAETITIA
摘要:The invention relates to novel triaminopyrimidine derivatives of formula (I) wherein Rl, R2, L, R3, R4a, R5a, R4b, R5b are variables. Said products have a Cdc25 phosphatase inhibiting activity. The invention also relates to a method for the synthesis of said compounds, to therapeutic compositions containing said products, and to the use thereof as medicaments.

专利号:US-8012220-B2
优先权日:2006-04-13
标题 :Specific monocationic monochromophoric compounds of hydrazone type comprising a 2-, 4-pyridinium or 2-, 4-quinolinium unit, synthesis thereof, dye compositions containing them, and method for dyeing keratin fibres
发明人：DAVID HERVE; MURGUET NADEGE; GREAVES ANDREW
权利人:OREAL
摘要:The present disclosure relates to monocationic monochromophoric compounds of formula (I) and (II) and dyeing compositions and multicompartment devices comprising monocationic monochromophoric compounds of formula (I) and (II). The disclosure also relates to methods for preparing monocationic monochromophoric compounds of formula (I) and (II), and also to methods for dyeing comprising applying monocationic monochromophoric compounds of formula (I) and (II) to keratin fibers.