CAS: 2724-59-6; 17-Methylstearic Acid

该化合物是一种分链脂肪酸,是石酸的衍生物,其特点是附于石酸链17碳的甲基组,由18个碳原子组成,饱和.这种结构改变会影响其物理和化学特性,如熔点和溶解性.通常,17甲基硫酸在室内温度下是一种白色,蜡状固体,在水中溶解,但在有机溶剂中溶解.它被用于各种用途,包括表面活性剂,乳化剂和其他化学化合物的合成.该甲基组的存在也会影响其生物活动和其他分子的相互作用.与许多脂肪酸一样,它可能表现出不同程度的毒性和环境影响,需要在工业应用中仔细处理和考虑.总的来说,17甲基硫酸是有机化学和材料科学中的重要化合物.

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2724-58-5 4669-02-7 5963-14-4

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合成工艺路线路线简述

    📜异硬脂醇置于水,三乙胺,Sodium Hydroxide体系中,用 四氢呋喃,乙醇,二氯甲烷,二甲基亚砜 用作溶剂,化学反应 72.25H,反应生成17-甲基硬脂酸
    参考文献:长链异脂肪酸 (Iso-C12-C19) 和相关天然产物的实用合成.
    标题:长链异脂肪酸 (Iso-C12-C19) 和相关天然产物的实用合成.
    摘要:从十一碳烯酸甲酯(十一碳烯酸甲酯)(对于异 C12-C14)或 C15 和 C16 内酯十五烷内酯开始,开发了末端支化异脂肪酸(iso-C12-C19)的克级合成(异-C15-C17)和十六烷内酯(异-C18-C19).概述的方法的核心是通过将甲基溴化镁添加到酯/内酯和选择性还原所得叔醇来两步构建末端异丙基.因此,C12,C17 和 C18 异脂肪酸是从市售原料中分三步获得的,其余的 C13-C16 和 C19 异脂肪酸通过这些脂肪酸的同系或递归脱同系或通过拦截来制备合适的中间体.
    Doi:10.3762/bjoc.9.210

    海关参考信息

    专利信息


    专利号:US-6861416-B2
    优先权日:2001-08-03
    标题 :Oxazinones and methods for their use and synthesis
    发明人:WOLFE SAUL; SHUSTOV GENNADY
    权利人:CHIROLOGIX PHARMACEUTICALS INC
    摘要:The invention pertains, at least in part, to new intermediates and synthetic methods for the stereospecific synthesis of oxazinone compounds, which are useful, for example, as antibiotics. The invention also pertains to novel olefinic oxazinone compounds, methods for their synthesis, and methods of using these compounds for the synthesis of oxazinones. The invention also pertains to methods for using the compounds to treat bacterial associated states in subjects.

    专利号:US-2017246690-A1
    优先权日:2014-06-20
    标 题:Stabilizing agent-free metal nanoparticle synthesis and uses of metal nanoparticles synthesized therefrom
    发明人:MURPHY RYAN J; DREYFUS REMI; HOUGH LAWRENCE ALAN; MALASSIS LUDIVINE; MURRAY CHRISTOPHER; DONNIO BERTRAND
    权利人:RHODIA OPERATIONS; CENTRE NAT RECH SCIENT; UNIV PENNSYLVANIA
    摘要:Described herein are methods of synthesizing metal nanoparticles and the metal nanoparticles synthesized therefrom. Further described in the present disclosure are methods of modifying the surfaces of metal nanoparticles and the metal nanoparticles modified thereby. Also described herein are uses of such metal nanoparticles.

    专利号:US-6214875-B1
    优先权日:1998-04-14
    标题:Anticancer effects of specific branched-chain fatty acids and related production process
    发明人:YANG ZHENHUA
    摘要:A group of specific branched-chain fatty acids, with significant anticancer effects on human and animals; methods of making using either chemical synthesis or biosynthesis methods; and methods of treating cancer.

    专利号:CN-106852132-A
    优先权日:2014-06-20
    标题:Stabilizer-free synthesis of metal nanoparticles and use of metal nanoparticles synthesized therefrom

    专利号:WO-2004096171-A1
    优先权日:2003-04-29
    标题 :Skin whitening cosmetic composition comprising the extract of machilus thunbergii and the compounds isolated therefrom
    发明人:SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK
    权利人:YEUNGNAM EDUCATIONAL FOUND; SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK
    摘要:The present invention is related to a cosmetic composition comprising the extract of Machilus thunbergii and lignan compounds isolated therefrom having potent inhibitory effect on melanin synthesis. Inventive composition shows the excellent inhibitory activity on cultured B-16 melanoma cell therefore, it can be useful in skin whitening cosmetic composition as an cream, skin, lotion, pack and the like.

    专利号:US-7858600-B2
    优先权日:2000-03-31
    标 题 :7- and 9- carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
    发明人:NELSON MARK L; LEVY STUART B; FRECHETTE ROGER; BOWSER TODD; ISMAIL MOHAMED Y
    权利人:PARATEK PHARM INNC; TUFTS COLLEGE
    摘要:Substituted tetracycline compounds, methods of synthesis, and methods of use are discussed. Tetracyclines useful for treating tetracycline related disorders are also discussed. Intermediates useful for synthesizing other tetracycline compounds are also included.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: T N R Srinivas, Et Al. Cesiribacter Andamanensis Gen. Nov., Sp. Nov., Isolated From A Soil Sample From A Mud Volcano. Int J Syst Evol Microbiol. 2011 Jul;61(Pt 7):1521-1527.

    合成参考文献


    参考文献:10.1007/bf02631958
    摘要:Freeman NK. Applications of infrared absorption spectroscopy in the analysis of lipids. J Americ Oil Chem Soc. 1968 Nov;45(11):798–809. doi: 10.1007/bf02631958.
    参考文献:10.1007/bf02536306
    摘要:Carballeira NM, Shalabi F. The rare Caribbean sponge Leucosolenia canariensis: phospholipid fatty acids and sterols. Lipids. 1995 May;30(5):467–70. doi: 10.1007/bf02536306.
    参考文献:10.1007/bf02535849
    摘要:Barnathan G, Mirallès J, Gaydou EM, Boury‐Esnault N, Kornprobst J. New phospholipid fatty acids from the marine spongeCinachyrella alloclada uliczka. Lipids. 1992 Oct;27(10):779–84. doi: 10.1007/bf02535849.
    参考文献:10.1007/s10811-023-03038-4
    摘要:Krivina ES, Savchenko TV, Tebina EM, Shatilovich AV, Temraleeva AD. Morphology, phylogeny and fatty acid profiles of Meyerella similis from freshwater ponds and Meyerella krienitzii sp. nov. from soil (Trebouxiophyceae, Chlorophyta). J Appl Phycol. 2023 Jul 07;35(5):2295–307. doi: 10.1007/s10811-023-03038-4.
    参考文献:10.1007/s12520-025-02241-3
    摘要:Ding L, Wang L, Lyu Q, Yang Q, Yang Y. New insights of subsistence practices in the late Shang period of upper reaches of Hutuo river, Xinding basin, Shanxi Province: lipid residue evidence. Archaeol Anthropol Sci. 2025 May 28;17(6). doi: 10.1007/s12520-025-02241-3.
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