CAS: 2495-96-7; N-((2R,3R,4R,5S,6R)-2-Ethoxy-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-yl)Acetamide

该化合物是N-eterylglucosamine的胶质衍生物,通常用于血液生物学和碳水化合物化学研究,其乙基甘基边联系与免费减少糖相比增强了稳定性,使其适合用于酶和合成研究.β配置确保与生物系统兼容,特别是在研究甘油和甘油酶转移酶活动方面.该化合物是合成寡醇酸盐和甘醇基甲的有价值的中间体,对立体化学进行精确控制.其在极地有机溶剂和水中的溶性促进了多种实验应用.研究人员在对碳水化合物加工酶的机械性研究中支持其明确的结构和可靠性.

英文名称N-((2R,3R,4R,5S,6R)-2-Ethoxy-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-yl)Acetamide
中文名称乙基 2-(乙酰氨基)-2-脱氧-β-D-吡喃葡萄糖苷
IUPAC名称N-((2R,3R,4R,5S,6R)-2-ethoxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide
其它别名十二烷基-β-D-吡喃半乳糖苷; Ethyl 2-Acetamido-2-Deoxy-Beta-D-Glucopyranoside
CAS编号2495-96-7
MFCD编号:MFCD12407878
分子式:C10H19NO6分子量:249.26
产品CID: 1203208
产品分类有机原料→分子砌块→手性化合物→手性砌块

相似结构搜索
InChIKey: KRABAWXNIPSDEF-UHFFFAOYSA-N
InChI=1S/C10H19NO6/c1-3-16-10-7(11-5(2)13)9(15)8(14)6(4-12)17-10/h6-10,12,14-15H,3-4H2,1-2H3,(H,11,13)/t6-,7-,8-,9-,10-/m1/s1
计算化学: 氢键受体数6.0氢键供体数4可旋转键数4

相似化合物

7784-54-5 76375-60-5 3006-60-8

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501

上下游产品

合成工艺路线路线简述

合成目标产物 Ethyl 2-Acetamido-2-Deoxy-Beta-D-Glucopyranoside 主要起始原料 Ethyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside
(文献来源)合成步骤主要原料 Ethyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside

📜2-乙酰氨基-3,4,6-三-O-乙酰-2-脱氧-α-D-吡喃葡萄糖酰基氯置于甲醇,Sodium Methylate,氰化汞体系中,化学反应 27.0H,反应生成乙基-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷
参考文献:Discovery Of The Chemical Function Of Glycosidases: Design,Synthesis,And Evaluation Of Mass-Differentiated Carbohydrate Libraries
标题:Discovery Of The Chemical Function Of Glycosidases: Design,Synthesis,And Evaluation Of Mass-Differentiated Carbohydrate Libraries
摘要:Discovery Of The Catalytic Chemical Function Of The Many Putative Glycosidases Coded In Genomes Currently Relies On Individual Testing Of Possible Substrates,Usually As Their P-Nitrophenol Conjugate. Herein,We Present An Alternative Chemical Proteomics Approach Using A Synthetic Mass-Differentiated Heat-Stable Substrate Library With Mass Spectrometry Readout. Library Components Do Not Serve As Reaction Inhibitors And Both Primary And Secondary Enzyme Substrates Can Be Delineated.
Doi:10.1021/ol049389B

海关参考信息

2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-8816050-B2
优先权日:2006-03-22
标题:Method of preparing glycopeptides
发明人：WONG CHI-HUEY; BRIK ASHRAF; YANG YU-YING; FICHT SIMON; PAYNE RICHARD
权利人:WONG CHI-HUEY; BRIK ASHRAF; YANG YU-YING; FICHT SIMON; PAYNE RICHARD; SCRIPPS RESEARCH INST
摘要:A method is provided for the synthesis of glycopeptides using a sugar assisted ligation strategy, wherein an N-terminal peptide portion in the form of a thioester is coopled with a C-terminal peptide portion bearing a carbohydrate moiety comprising a thiol group.