CAS: 236406-55-6; 2-(Tert-Butoxycarbonyl)-2,7-Diazaspiro[3.5]Nonane

上下游产品

N-Boc-苄基-2,7-二氮杂螺环[3.5]正壬烷 Tert-Butyl 7-Benzyl-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate 929301-99-5

N-Boc-苄基-2,7-二氮杂螺环[3.5]正壬烷置于palladium 10% On Activated Carbon,氢气体系中,用 甲醇 用作溶剂,20.0 °C,101.33 Kpa 条件下,反应 96.0H,反应生成2-叔丁氧羰基-2,7-二氮杂螺[3.5]壬烷
参考文献: Substituted Nucleoside Analogues For Use As Prmt5 Inhibitors[fr] Analogues De Nucléosides Substitués Destinés à être Utilisés En Tant Qu'Inhibiteurs De Prmt5
标题: Substituted Nucleoside Analogues For Use As Prmt5 Inhibitors[fr] Analogues De Nucléosides Substitués Destinés à être Utilisés En Tant Qu'Inhibiteurs De Prmt5
摘要:本发明涉及式(I)的新型取代核苷类似物,其中变量具有如权利要求中所定义的含义.根据本发明的化合物作为prmt5抑制剂是有用的.本发明进一步涉及包含所述化合物作为活性成分的药物组合物,以及将所述化合物用作药物的应用.

专利信息

专利号:US-2012010186-A1
优先权日:2009-03-23
标题:Heterocyclic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LACHANCE NICOLAS; LEGER SERGE; OBALLA RENATA M; POWELL DAVID; TRANMER GEOFFREY K; MARTINS EVELYN; GAREAU YVES
权利人:LACHANCE NICOLAS; LEGER SERGE; OBALLA RENATA M; POWELL DAVID; TRANMER GEOFFREY K; MARTINS EVELYN; GAREAU YVES; MERCK FROSST CANADA LTD
摘要:Heterocyclic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease; atherosclerosis; obesity; diabetes; neurological disease; Metabolic Syndrome; insulin resistance; cancer, liver steatosis; and non-alcoholic steatohepatitis.

专利号:CN-118272840-A
优先权日:2024-04-07
标题:Method for electrochemical synthesis of thiocarbamate-labeled tyrosine-containing biomolecules

专利号:CN-114249680-B
优先权日:2022-01-10
标 题:A kind of indole derivative and its synthesis method and application