CAS: 23094-71-5; 1-O-Galloyl-2,4-O-Chebuloyl-3,6-O-Hhdp-β-D-Glucose

该化合物是一种自然产生的多元酚化合物,主要存在于传统医学常用的绝地树果中,被归类为,以其抗氧化特性而著称,有助于其潜在的健康利益; 酸的化学结构具有多种氢氧基组,这增强了其排泄自由基和表现出抗炎效应的能力; 该化合物已引起人们对其潜在治疗应用的兴趣,包括其在促进消化健康及其可能的抗癌特性方面的作用. 此外,酸可能会影响各种生物化学途径,使其成为药理学和营养学研究的课题,水和有机溶剂的溶性各不相同,会影响其生物利用率和不同配方的功效.

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CAS号1707-75-1 1,1-二苯基-2-苦味酰肼

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    专利信息


    专利号:WO-2006101119-A1
    优先权日:2005-03-22
    标 题 :Collagen synthesis promoter
    发明人:TACHIKAWA MASAMI; KARAKIDA FUMITO; KAWAKAMI ZENJI; MATSUURA DAISUKE; KANATANI HIROTOSHI
    权利人:TSUMURA & CO; TACHIKAWA MASAMI; KARAKIDA FUMITO; KAWAKAMI ZENJI; MATSUURA DAISUKE; KANATANI HIROTOSHI
    摘要:A collagen synthesis promoter capable of exhibiting a satisfactory collagen synthesis promoting activity and a high skin conditioning potency. There is provided a collagen synthesis promoter comprising as an active ingredient an extract from the fruit of myrobalan, and provided a collagen synthesis promoter comprising as an active ingredient one or two or more members selected from the group consisting of chebulagic acid, chebulinic acid, gallic acid and corilagin. The provided collagen synthesis promoter is suitable for use as a skin external preparation or skin quality improver; and can impart moistness and suppleness to the skin, can effect texture conditioning and can sustain the water retaining power of superficial skin.

    专利号:US-12036300-B2
    优先权日:2021-03-31
    标题:Methods and compositions for improving skin
    发明人:LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
    权利人:OREAL
    摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.

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    主要参考文献


    1: Yang L, Liu Y, Zhang W, Hua Y, Chen B, Wu Q, Chen D, Liu S, Li X. Ferroptosis-Inhibitory Difference between Chebulagic Acid and Chebulinic Acid Indicates Beneficial Role of HHDP. Molecules. 2021 Jul 15;26(14):4300. doi: 10.3390/molecules26144300.
    2: Vasu G, Sundaram R, Muthu K. Chebulagic acid attenuates HFD/streptozotocin induced impaired glucose metabolism and insulin resistance via up regulations of PPAR γ and GLUT 4 in type 2 diabetic rats. Toxicol Mech Methods. 2022 Mar;32(3):159-170. doi: 10.1080/15376516.2021.1976333. Epub 2021 Sep 22.
    14:1143427. doi: 10.3389/fphar.2023.1143427.

    合成参考文献


    参考文献:10.1155/2012/125247
    摘要:Chang CL, Lin CS. Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect ofTerminalia chebulaRetzius Extracts. Evidence-Based Complementary and Alternative Medicine. 2012;2012():1–7. doi: 10.1155/2012/125247.
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